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  • 1
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:   The importance of the CYP1A1 polymorphisms at exon 7 (Ile/Val) and 3′-untranslated region (3′-UTR) has been controversial in oral squamous cell carcinoma (OSCC) or head and neck SCC (HNSCC) denoting the value of exploring the correlation between these polymorphisms and risk of betel/smoking associated OSCC. It is also important to evaluate the association between CYP1A1 polymorphisms and susceptibility of oral precancerous lesion (OPL) to confirm the findings in OSCC cases.Methods:   We examined polymorphic prevalence of CYP1A1 at exon 7 (Ile/Val) and 3′-UTR in 106 cases with OSCC, 60 cases with OPL, and 146 controls. DNA isolated from surgical specimens and whole blood was used for PCR-based genotyping.Results:   The prevalence of the CYP1A1 A/G genotype (Ile/Val) and G/G genotype (Val/Val) in exon 7 of cases with OSCC (79.2 and 7.6%) and OPL (68.3 and 10%) were significantly higher than in controls (53.4 and 1.4%) (P 〈 0.0001). The novelty of the present study is that we identified the onset age of OSCC in CYP1A1 A/G genotype to be significantly younger than that in A/A genotype (P 〈 0.01). No significant difference was seen between cases and controls regarding the polymorphisms at 3′-UTR.Conclusion:   The findings indicate that the individuals with the CYP1A1 exon 7 containing G allele were at increased risk for OSCC and OPL.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 505-507 (Jan. 2006), p. 169-174 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Brookfield, Conn. : Wiley-Blackwell
    Polymer Composites 15 (1994), S. 289-298 
    ISSN: 0272-8397
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This work discusses tow independent methods to measure and analyze the trans-plane fjuid permeability of various fiber reinforcements. In the unidirectional flow method, the measured injection pressure and flow rate, together with a one-dimensional Darcy's law were used to calculate the trans-plane permeability of fiber mats was independent of flow rate only at low injection pressure. Flow-induced fiber mat permeability change occurred when the injection pressure exceeded the clamping pressure. Measured permeability in conjunction with a three-dimensional mold filling computer program was used to simulate the effect of stacking sequence for a combination of different fiber mats on the mold filling pattern. Finally, a method is proposed to simplify the simulation of a three-dimensional flow through the fiber perform.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
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