ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Steroides. LXX. Stereoselective Epoxidation of 14,15-Unsaturated Estratriene-3-methyl Ethers. On the syn-Directive Effect of UrethanesThe stereochemistry of the epoxidation of 14,15-unsaturated estratriene-3-methyl ethers with peroxyacids is examined. The influence of different 17-substituents and of the solvent on the stereoselectivity is discussed. Whereas on epoxidation of 17β-esters and 17β-ethers mainly 14α, 15α-epoxides are formed (up to 89%), the 17β-urethane derivatives yield the 14β, 15β-epoxides up to 87% by a syn-directive effect.
Additional Material:
5 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19813230513
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