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  • 1
    Electronic Resource
    Electronic Resource
    Relation Between Growth Hormone and Somatomedin (1975)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 26 (1975), S. 427-441 
    Details
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.me.26.020175.002235
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  • 2
    Electronic Resource
    Electronic Resource
    Pulpal response to a bis-acryl-plastic (Protemp®) temporary crown and bridge material (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 13 (1984), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The pulpal response to Protemp® (ESPE Gmbh) was compared to zinc oxide-eugenol, Super Syntrex (de Trey) and Protemp® plus zinc oxide-eugenol liner in 144 vervet monkey (Cercopilhecus pygerythus) incisor teeth, according to ADA Specification No. 41. Cellular displacement into dentinal tubules, superficial and deep inflammation were present only in the 3-day specimens in all materials. Mean scores for the test material were lower than both negative and positive controls. In the 30-day specimens the prevalence of reparative dentine under the test material was similar to the negative control, while at 90 days it was less than (he negative control, although the severity in affected specimens was more than the positive control. Use of a zinc oxide-eugcnol liner reduced the severity of reparative dentine formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1984.tb01464.x
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  • 3
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    Unknown
    The evaluation of an integrated parent-training program (1983)
    Worcester, Mass. : Periodicals Archive Online (PAO)
    Journal of Social Psychology. 121:2 (1983:Dec.) 273 
    Details
    ISSN: 0022-4545
    Topics: Psychology , Sociology
    Notes: Social Psychology in South Africa
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1143-1983-121-02-000016
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  • 4
    Electronic Resource
    Electronic Resource
    A Novel Electrostatic Machine: the Corona Motor (1961)
    [s.l.] : Nature Publishing Group
    Nature 192 (1961), S. 649-650 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The motor is shown in Fig. 1 and consists of a disk, made from an insulating material, which is mounted on a spindle, and three pairs of electrodes mounted circumferentially around the disk. The electrodes are alternately connected to the positive and negative terminals of a source of high-voltage ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/192649b0
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  • 5
    Electronic Resource
    Electronic Resource
    A Function Multiplier (1956)
    [s.l.] : Nature Publishing Group
    Nature 178 (1956), S. 1247-1248 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The principle of multiplication is based on a geometrical system, namely, a rectangular area which is deflected relative to a system of rectangular axes. The axes divide the rectangular area into four rectangles, A, B, C and D, which are equal in area in its undetected position. The areas in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1781247a0
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  • 6
    Electronic Resource
    Electronic Resource
    Biological Sciences: Papova Virus in Urine after Renal Transplantation (1973)
    [s.l.] : Nature Publishing Group
    Nature 241 (1973), S. 343-344 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The patients (Table 1) had received renal allografts between thirteen and twenty-two months before the start of the investigation. Thirteen patients received kidneys from dead donors, four had kidneys from living donors, while one patient received a second kidney (from his mother) after removal of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/241343a0
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  • 7
    Electronic Resource
    Electronic Resource
    Reflection of Atmospherics from the Ionosphere (1939)
    [s.l.] : Nature Publishing Group
    Nature 143 (1939), S. 893-894 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE details of the structure of the ‘oscillatory’ portion of the wave-form of an atmospheric have been the subject of several investigations1. Prof. T. H. Laby and his co-workers of the Australian Radio Research Board have made the remarkable suggestion that the observed ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/143893a0
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  • 8
    Electronic Resource
    Electronic Resource
    An investigation of the mechanism of detoxification in asbestos (1992)
    Springer
    Hyperfine interactions 73 (1992), S. 377-381 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract 57Fe Mössbauer effect spectroscopy studies were conducted on native crocidolite and on a sample which had been detoxified by means of a chemical treatment with ferric salts. This allows for a comparison between the crystal chemistry of the untreated and treated samples. Significant chemical changes in the treated sample have been inferred from the Fe site-population analysis after conducting a temperature-dependent study of both samples in the range 300 K down to 90 K. These results, together with the results from complementary Electron Spin Resonance (ESR) studies, may help to elucidate the mechanism of toxicity in these asbetiforms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02418612
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  • 9
    Electronic Resource
    Electronic Resource
    Mitogenic activity of hydroxyapatite: Requirement for somatomedin C (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 128 (1986), S. 143-148 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Synovial hyperplasia is a feature of the chronic synovitis associated with basic calcium phosphate crystals [hydroxyapatite (HA), octacalcium phosphate, tri-calcium phosphate] and calcium pyrophosphate. Each of these crystals stimulated mitosis of cultured human skin fibroblasts or canine synovial fibroblasts in a concentration-dependent fashion. We examined the effect of pure somatomedin C (Sm-C) on HA crystal induced mitogenesis. Confluent cultures of human fibroblasts were rendered quiescent by incubation in the presence of 1% platelet-poor-Sm-C free plasma (PPSCFP) for 24 hours. HA crystals stimulated thymidine incorporation 2.3-fold over control value. Addition of Sm-C significantly augmented the effect of HA crystals (P 〈 0.01). Nearly identical effects were observed in the presence of 100 μg/ml HA crystals or 15 ng/ml PDGF. Monoclonal antibodies against Sm-C had little effect on the basal 3H thymidine uptake by control cells incubated in 1% PPSCFP but blocked over 50% of the HA crystal of PDGF-induced 3H thymidine incorporation both in the presence or absence of Sm-C. The incomplete blocking suggested either the presence of other “progression” factors, such as insulin-like growth factor II in the conditioned media or the possibility that HA or PDGF in high enough dosage enabled cells to escape their dependence on Sm-C for DNA synthesis.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041280202
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  • 10
    Electronic Resource
    Electronic Resource
    Demonstration of type I and type II somatomedin receptors on bovine growth plate chondrocytes (1988)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 6 (1988), S. 817-826 
    Details
    ISSN: 0736-0266
    Keywords: Somatomedin ; Receptors ; Growth plate ; Chondrocytes ; Affinity labeling ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The chondrocytes of the epiphyseal growth plate are the presumed target cells for hormones regulating skeletal growth. The somatomedins, a family of low molecular weight peptides, are thought to play a stimulatory role in this regulation. The cellular actions of the somatomedins are themselves determined by binding to specific receptors on target cells. Previous studies have characterized a specific receptor for somatomedin-C (Sm-C) or insulin-like growth factor I (IGF-I) on bovine growth plate chondrocytes (GPCs). We now report the characterization of a second type of somatomedin receptor on these cells that is more specific for another class of somatomedin represented by multiplication-stimulating activity (MSA) or rat insulin-like growth factor II (rIGF-II). Binding of [125I]MSA/rIGF-II to isolated GPCs was time dependent and saturable. Unlabeled Mr 7.100 MSA/rIGF-II and Sm-C/IGF-I were approximately equipotent in competing with [125I] MSA/rIGF-II for binding. while Mr 8,600 MSA/rIGF-II was an order of magnitude less potent. Low levels of competition by insulin appeared in some studies at concentrations of 10-7 M and higher. suggesting displacement of [125I]MSA/rIGF-II binding. to the Sm-C/IGF-I receptor. In affinity-labeling studies. [125I]Sm-C/IGF-I labeled a complex of Mr 〉300.000 (unreduced) and of Mr 140.000 (reduced). consistent with a type I somatomedin receptor composed of disulfide-linked subunits. [125I]MSA/rIGF-II labeled a Mr 240.000 moiety (unreduced) and Mr 260.000 (reduced). consistent with a type II somatomedin receptor. Both affinity-labeling and kinetic data revealed cross-binding of MSA/rIGF-II and insulin with the type I receptor and of Sm-C/IGF-I with the type II receptor. In contrast. the type II receptor did not recognize insulin. These data suggest a complex pattern of graded specificity of these receptors for their ligands. These data are consistent with the hypothesis that IGF-II as well as Sm-C/IGF-I participate in the stimulation of skeletal growth.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100060605
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