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  • 1
    ISSN: 1435-5604
    Keywords: Dual photon absorptiometry ; Lumbar bone mineral density ; Fracture threshold ; Aging ; Jikei University Classification of Lumbar Bone Loss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using a dual photon absorptiometer Dualomex HC-1 based on the scinticamera system utilizing153Gd, bone density of the lumbar vertebrae was measured to set up normative values for each group in both sexes along with fracture threshold. Bone density of the lumbar spine was measured in 712 male and female subjects ranging in age between 16 and 96 years at 11 medical instructions all over Japan, to establish normative values for each age and sex group. The peak bone mass of 0.75 g/cm2 was reached in the 30s in males and that of 0.76 g/cm2 in the 40s in females. The lumbar spine density obtained by this method showed good parallelism with the Singh index and degree of lumbar spine bone loss according to Jikei University method. A high correlation was also found between the bone density obtained by this method and that obtained by Lunar DP-4 (r=0.902, n=28). Spinal compression fracture was found in about 2/3 of the subjects with L2 – L4 bone density measured in the anterior-posterior direction of less than 0.58 g/cm2 and 3/4 of those with the corresponding value less than 0.49 g/cm2. Bone density less than 0.49 g/cm2 was therefore tentatively called the range predicting fracture (dangerous range) and that between 0.49 and 0.58 as the range warning fracture (warning range).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of bone and mineral metabolism 9 (1991), S. 25-28 
    ISSN: 1435-5604
    Keywords: Epidemiology ; Hip fractures ; Distal radius fractures ; Proximal humerus fractures ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We review the results of our investigation of the incidence of fractures of the proximal femur, distal radius, and proximal humerus, in Tottori Prefecture, Japan, and compared our results with those found previously in other countries. During the period from 1986 to 1988, 918 proximal femoral, 1103 distal radial, and 260 proximal humeral fractures in patients over 35 years of age were recorded in Tottori Prefecture. In all fracture types, age-and sex-specific incidence was lower among Japanese than among European or North American whites.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1436-2813
    Keywords: gastrectomy ; bone mineral content ; serum minerals ; vitamin D
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To study post-gastrectomy metabolic bone disorders, we measured the radial bone mineral content (BMC), serum levels of calcium, inorganic phosphorus, alkaline phosphatase, and 25-hydroxyvitamin D(25-OH-D) in 59 patients with partial- and 39 patients with total gastrectomy. Total gastrectomy patients manifested a higher incidence of decreased BMC levels than did partial gastrectomy patients (56 per centvs. 25 per cent). Patients subjected to the Billroth II procedure, especially females, manifested abnormally low BMC values. The decline in BMC was age-related; it was pronounced in females. At 10 years postoperatively, many of the partial gastrectomy patients manifested markedly low BMC levels; in totally gastrectomized patients this finding was made at less than 5 years postoperatively. Approximately 30 per cent of our patients showed abnormalities in serum minerals, alkaline phosphatase or 25-OH-D.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of bone and mineral metabolism 11 (1993), S. S15 
    ISSN: 1435-5604
    Keywords: Ipriflavone ; Osteoporosis ; Bone mass ; Single-photon absorptiometry ; Dual-energy x-ray absorptiometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ipriflavone (IP) 600 mg/day was administered for 1 year to osteoporotic females either as a single continuous daily dose or as the depressor component of activate-depress-free-repeat (ADFR) therapy. The effects of IP, an inhibitor of bone resorption, on bone mass density (BMD) were examined. Studies of both groups, the single-dose regimen group and the ADFR therapy group, revealed not only that the BMD was maintained, but that it actually increased in the metaphysis of the radius when measured using single-photon absorptiometry. In the group administered IP as a single-dose regimen, 36.4% of the subjects showed an increase of more than 3% in BMD. In the ADFR group, using IP as the depressor, 45.5% showed an increase of more than 3% in the BMD of the metaphysis of the radius. In the control group using lactocalcium as a placebo, 14.3% of the patients showed an increase of more than 3% in the BMD of the metaphysis of the radius. IP effectively increased BMD in the early stages of bone loss. Measurements of BMD of the lumbar vertebrae (L2–L4), however, showed no significant differences between the control group and the two groups receiving IP.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1435-5604
    Keywords: calcitonin-elcatonin ; DXA ; bone mineral density ; osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 127 patients with involutional osteoporosis were randomly divided into two groups. The elcatonin group consisted of 67 patients who received 20 units of elcatonin per week administered intramuscularly, together with 0.6g calcium lactate (100mg as calcium) given orally three times daily for 24 weeks. The other 60 patients were assigned to a control group receiving 0.6g calcium lactate orally three times daily. Forty patients were withdrawn from the study treatment or dropped out during the study. The other 87 patients (consisting of 45 in the elcatonin group, and 42 in the control group) were measured for lumbar vertebral bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA). The BMD was increased significantly (P 〈 0.05) by 1.87 ± 0.79% (mean ± standard error) in the elcatonin group and decreased by 0.61 ± 0.93% in the control group at the end of the study. The difference between the two groups was statistically significant (P 〈 0.05). The results of the present study demonstrated that elcatonin increases the BMD in patients with involutional osteoporosis.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of orthopaedic science 5 (2000), S. 356-360 
    ISSN: 1436-2023
    Keywords: Key words Distal radius fractures ; Children and adoles-cents ; Epidemiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate recent trends in the incidence of fractures in children and adolescents, we conducted a survey of distal radius fractures in 1992 and 1995 in Tottori Prefecture, Japan. Seven-hundred and forty-five patients under age 20 years were registered (562 males and 183 females). The age and sex-specific incidences of fractures in patients under 20 years of age were higher in males than in females, showing peaks at age 12–13 years for males and at age 10–11 years for females. The incidences had an obvious monthly variation, with peaks in spring and autumn. The age and sex-specific incidences were compared with those in the period 1986–1988, which we reported previously. The incidence in each year showed a significant increase with time for males but not for females. We conclude that the incidence of distal radius fractures in children and adolescents has a prominent peak matched by the age of the growth spurt, and the incidence of the fracture has increased in males during the past decade in Tottori Prefecture.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of bone and mineral metabolism 9 (1991), S. 14-16 
    ISSN: 1435-5604
    Keywords: Epidemiology ; Osteoporosis ; Hip Fractures ; Distal Radius Fractures ; Proximal Humeral Fractures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A fracture survey on osteoporotics was performed in Tottori Prefecture during the period from 1986 to 1988. The incidence of fractures of the hip, distal radius, and proximal humerus was lower among Japanese than among European or North American whites by comparing our results with those reported previously in other countries. A retrospective case control study was performed in patients with and without hip fractures, and we concluded that hip fractures have been related to various lifestyle variables.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of human genetics 28 (1983), S. 35-43 
    ISSN: 1435-232X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two female cases with r(14) syndrome, aged 14 and 16, were reported. Both cases had mental retardation, microcephaly, growth retardation, epilepsy and ataxia. But craniofacial dysmorphic features, typical to r(14) syndrome, were rarely observed. Bone mineral content was decreased in one of the cases. The cataracta and abnormal pigmentation of the retinae was observed in one of the cases.
    Type of Medium: Electronic Resource
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