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  • 1
    Electronic Resource
    Electronic Resource
    Characteristics of IK and its Response to Quinidine in Experimental Healed Myocardial Infarction (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 10 (1999), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: I*, and Quinidine in Healed Infarction. Introduction: Mechanisms and drug treatment of serious ventricular arrhythmias in patients with healed myocardial infarction (HMI) are incompletely understood, in part because the electrophysiology and pharmacology of myocytes from noninfarcted regions of HMI hearts are not well characterized. Methods and Results: We studied the delayed rectifier potassium current (IK) and quinidine responsiveness of single left ventricular subendocardial myocytes isolated from the region remote to the border zone of healed infarct myocardium (4 to 6 mm from scar edge) in cat hearts 2 months after coronary artery occlusion. Subendocardial cells isolated from corresponding regions of normal cat hearts provided controls. IK activation and tail currents were recorded using whole cell, voltage clamp techniques. Membrane capacitance of cells remote to HMI (187 ± 7 pF) was significantly greater than normal (155 ± 6 pF; P 〈 0.001). Action potential durations (APDs) recorded from myocytes in remote regions were prolonged (APD90= 247 ± 10 msec) compared to normal (214 ± 11 msec; P 〈 0.05). Quinidine (1 μM) significantly prolonged APD90 in normal cells but not in remote cells. Density of IK, (tail current) was significantly decreased in remote cells (3.1 ± 0.3 pA/pF) compared to normal (3.9 ± 0.3 pA/pF; P 〈 0.05). and voltage-dependent activation of IK was shifted in the positive direction. Quinidine had significantly less incremental blocking effect on IK already blunted by regional hypertrophy compared to its effect on normal cells in remote cells. IC550 shifted to 0.95 μM in remote cells compared with 0.50 μM in normal cells. Conclusion: Cells in noninfarct region remote from the scar are hypertrophied and display altered electrophysiology. Their reduced IK responsiveness to quinidine may explain, in part, failure of quinidine to prolong APD in such cells. Moreover, dispersion of repolarization may be decreased by the effect of quinidine on normal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1999.tb00265.x
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  • 2
    Electronic Resource
    Electronic Resource
    Regional Gradation of L-Type Calcium Currents in the Feline Heart with a Healed Myocardial Infarct (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 8 (1997), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: ICa in Healed Myocardial Infarction. Introduction: Abnormal action potentials in myocytes adjacent to 〉 2-month-uld feline LV myocardial infarcts (MI) may reflect alterations in Ca2+ currents (ICa). Methods and Results: We compared ICa, at 36°C, in subendocardial myocytes isolated from areas adjacent to MI and to ICa in cells from remote areas (〉 4 mm away; REM) and control cells from similar regions in normal hearts. Control (CON) myocytes had membrane capacitance of 234 ± 10 pF (n = 81 cells) compared to 305 ± 14 pF in REM (71 cells; P 〈 0.05 from CON) and 237 ± 11 pF (n = 55 cells) in MI (not different from CON). From Vh=−40 mV, peak ICa elicited by test potentials (−35 to +70 mV) were significantly larger in CON (−1746 ± 123 pA) and REM (−1795 ± 142 pA) compared to Ml (−1352 ± 129 pA) (P 〈 0.05). Peak 1(11 density was significantly reduced in REM (−6.0 ± 0.4 pA/pF) or MI (−5.7 ± 0.4 pA/pF, P 〈 0.05) compared to CON (−7.5 ± 0.4 pA/pF). Double exponential ICa decay was similar among groups. Half-inactivation potential (V0.5) was significantly shifted (hyperpolarizing direction) for MI (−29.1 ± 2.6 mV) and REM (−24.6 ± 1.2 mV) myocytes compared to −20.3 ± 1.0 mV in CON. MI slope factor (k; 9.0 ± 0.5) was significantly different from CON (6.8 ± 0.3) and RKM (7.3 ± 0.4). No differences in time course of recovery from inactivation were noted. Five millimolar Ba2+0 produced significant increases in ICa in CON and REM but an attenuated response in MI. Bay k8644 (1 μM) produced similar ICa increase in all groups. ICa increase due to isoproterenol (1 ICaM) in MI and REM was half that in CON, but there were no differences in increased ICa responses among groups following phenylephrine (10 μM). Conclusion: Reduced ICa density in REM reflects cell hypertrophy, whereas altered ICa of MI may reflect altered channel structure and/or function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1997.tb00823.x
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  • 3
    Electronic Resource
    Electronic Resource
    Sonic points and shocks in isothermal accretion and winds in Kerr geometry (1996)
    Springer
    Astrophysics and space science 246 (1996), S. 197-210 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract This paper is devoted to the study of sonic points and shocks in stationary, axially symmetric, isothermal flows around a Kerr black hole. We first show the dependence of the location of the sonic point with the flow's angular momentum for different isothermal sound speeds. With our selected shock jump conditions, we then discuss the properties of the shock, including the location and the strength. The ambiguity regarding the shock locations is removed by stability analysis. We also find some differences between the shock in isothermal flows and that in adiabatic flows. Subject headings: accretion, accretion disks-black hole physics-hydrodynamics-relativity-shock waves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00645640
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  • 4
    Electronic Resource
    Electronic Resource
    Classification and asymptotic scaling of the light-cone wave-function amplitudes of hadrons (2004)
    Springer
    The European physical journal 33 (2004), S. 75-90 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We classify the hadron light-cone wave-function amplitudes in terms of parton helicity, orbital angular momentum, and quark-flavor and color symmetries. We show in detail how this is done for the pion, $\rho$ meson, nucleon, and delta resonance up to and including three partons. For the pion and nucleon, we also consider four-parton amplitudes. Using the scaling law derived previously, we show how these amplitudes scale in the limit that all parton transverse momenta become large.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjc/s2003-01563-y
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  • 5
    Electronic Resource
    Electronic Resource
    Pseudogap effects on the c-axis charge dynamics in copper oxide materials (2000)
    Springer
    The European physical journal 15 (2000), S. 607-614 
    Details
    ISSN: 1434-6036
    Keywords: PACS. 71.27.+a Strongly correlated electron systems; heavy fermions - 72.10.-d Theory of electronic transport; scattering mechanisms - 74.72.-h High- compounds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: The c-axis charge dynamics of copper oxide materials in the underdoped and optimally doped regimes has been studied by considering the incoherent interlayer hopping. It is shown that the c-axis charge dynamics for the chain copper oxide materials is mainly governed by the scattering from the in-plane fluctuation, and the c-axis charge dynamics for the no-chain copper oxide materials is dominated by the scattering from the in-plane fluctuation incorporating with the interlayer disorder, which would be suppressed when the holon pseudogap opens at low temperatures and lower doping levels, leading to the crossovers to the semiconducting-like range in the c-axis resistivity and the temperature linear to the nonlinear range in the in-plane resistivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100510051163
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  • 6
    Electronic Resource
    Electronic Resource
    Detection of Rotor Cracks Based on Multi-Scale Singular Spectrum Analysis (2003)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 245-246 (July 2003), p. 273-278 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/47/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.245-246.273.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    SiC Micro-Threads Prepared within the Carbon Fiber Felt (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 843-845 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Polyacrylonitrile (PAN) based carbon fiber felt which contains abundant various SiC microthreadsand some other microstructures was prepared through sintering the pretreated felt at hightemperature at low nitrogen pressure. XRD, SEM, TEM, HRTEM analyses for the sintered felt werecarried out to study its components and microstructures. There are SiC nanothreads, SiC submicronthreads, SiC micron threads and a few SiO2 two- or three-dimensional microstructures (possibly intermixwith the similar form of SiC) existed within the inner hollow spaces of the felt. The complex permittivity,complex permeability of the sample in the X-band frequency range were obtained
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.368-372.843.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    Long Term Load-Carrying Capacity of Eccentrically Compressed Concrete Filled Steel Tubular Members (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 302-303 (Jan. 2006), p. 651-657 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Based on the creep model of CFST members constructed with the Elastic Continuation and Plastic Flow theory of concrete creep and the creep theory of concrete under multi-axial stresses, the paper studies the load-carrying capacity of eccentrically compressed CFST members with consideration of creep. Some eccentrically compressed CFST members’ long-term loadbearing capacity is calculated and corresponding results are compared with the load-carrying capacity without consideration of creep. According to the analysis of calculating results, it can be concluded that creep will decrease the load carrying capacity of eccentrically compressed CFST members, and it should be paid enough attentions in actual engineering
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/50/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.302-303.651.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Age-Adjusted Effective Modulus Method for Creep of High-Performance Concrete (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 302-303 (Jan. 2006), p. 693-699 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper discusses the suitability of using several creep theories of common concrete for creep of high-performance concrete (HPC). Based on the Age-Adjusted Effective Modulus method (AEMM) for creep of concrete, Improved Dischinger (ID) method and the Elastic Continuation and Plastic Flow (ECPF) theory for calculating relaxation coefficient and considering characteristics of HPC, a method is set up for calculating the creep of HPC under changing stresses,and comparing results gotten by the method with some experimental data, it can be considered that the above methods are suit for the calculation of creep of HPC
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/50/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.302-303.693.pdf
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  • 10
    Electronic Resource
    Electronic Resource
    Evaluation of comparative protein modeling by MODELLER (1995)
    New York, NY : Wiley-Blackwell
    Proteins: Structure, Function, and Genetics 23 (1995), S. 318-326 
    Details
    ISSN: 0887-3585
    Keywords: evaluation ; comparative protein modeling ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: We evaluate 3D models of human nucleoside diphosphate kinase, mouse cellular retinoic acid binding protein I, and human eosinophil neurotoxin that were calculated by MODELLER, a program for comparative protein modeling by satisfaction of spatial restraints. The models have good stereochemistry and are at least as similar to the crystallographic structures as the closest template structures. The largest errors occur in the regions that were not aligned correctly or where the template structures are not similar to the correct structure. These regions correspond predominantly to exposed loops, insertions of any length, and non-conserved side chains. When a template structure with more than 40% sequence identity to the target protein is available, the model is likely to have about 90% of the mainchain atoms modeled with an rms deviation from the X-ray structure of ≈ 1 Å, in large part because the templates are likely to be that similar to the X-ray structure of the target. This rms deviation is comparable to the overall differences between refined NMR and X-ray crystallography structures of the same protein. © 1995 Wiley-Liss, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prot.340230306
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