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Notes: A three-camera close range photogrammetric system for robust and precise measurement of bedsores has been designed and constructed. MEDPHOS (MEDical PHOtogrammetric System) consists of three synchronised cameras with convergent optical axes. A light projector is fixed in the centre of the rig that holds the cameras. A special dot pattern is projected onto the surface to be measured, to compensate for the lack of natural texture on the wound surface. The proposed algorithm consists of the following steps: the cameras and projector are calibrated so that all interior and exterior parameters are known; tailored image segmentation procedures are developed and applied for the detection of the projected pattern dots from the uneven background of the images using morphologic operators; and watershed transformation is used to tackle the problem of overlapping pattern dots. To reduce the effects of non-uniform illumination and specular reflection of light due to humidity (often the case with wounds), a homomorphic transformation is developed and applied to the images. After segmentation of the images, a connected-component labelling procedure is used to establish the points for matching. The centroids of these components were precisely calculated. Intensity-based image matching has been tested without yielding satisfactory results due to the significant deviation from the Lambertian reflection assumption used for solving the correspondence problem. This problem is reliably solved by developing a new algorithm based on geometric constraints that allow feature-based matching and do not need approximate values of the location of the targets in the images. This robust three-focal constraint is found to be very effective for matching provided the necessary conditions for the system configuration are met. Auxiliary photometric constraints together with the calibrated projector (which is treated like an active camera) also serve as additional sources of information for reducing the number of remaining ambiguities and checking the consistency of the results. Almost all of the required biometric information can be obtained rapidly, robustly and easily using MEDPHOS. Experimental results showed the effectiveness of the proposed technique.