Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 31 (1997), S. 66-75 
    ISSN: 1432-0495
    Keywords: Key words Ground Penetrating Radar ; GPR ; Aquifer ; Analogue studies ; Sedimentology ; 3D structures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Applying the concept of "analogue studies" long used in reservoir characterization, outcrop analogues in two aquifer units of Southern Germany have been investigated: Upper Triassic (Keuper) alluvial sandstones (Stubensandstein) and Quaternary glaciofluvial gravels. Architectural element analysis of the outcrops is combined with ground-penetrating radar profiles derived a few meters behind the outcrop walls. Such calibration is used to better understand the three-dimensional sedimentary architecture. Many sedimentary units at the same time represent hydraulic flow units and are characterized by specific radar signatures. This approach leads to promising results, not only in unconsolidated aquifers but also in fully consolidated sedimentary rocks. Our studies will lead to a database with which more realistic predictions of the hydraulic behaviour of sedimentary aquifers systems, needed for numerical hydrogeological simulations, will be possible.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Rheumatologie 57 (1998), S. 178-178 
    ISSN: 0340-1855
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Rheumatologie 59 (2000), S. 348-351 
    ISSN: 0340-1855
    Keywords: Key words Rectal stricture –¶cyclooxygenase inhibitor –¶ibuprofen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Here, we report the case of a 64-year-old woman who suffered from chronic lower backache for which she received ibuprofen suppositories. The patient was admitted to the hospital with a suspected rectal tumor. Clinical examination did not reveal any abnormal finding apart from a mild, bilateral peritibial edema. On rectal examination, an area of stenosis was detected approximately 7 cm above the anal verge. All laboratory parameters, including different tumor markers, were within normal range. Pelvic CT scan and colonoscopy revealed a circular rectal stenosis with severe destruction of the rectal mucosa. The rectal biopsy taken during endoscopy showed severe acute and chronic ulceration, chronic granulation and fibrosis with lymphocytic infiltration. After exclusion of sexually transmitted diseases such as syphilis and lymphogranuloma venerium or exposure to drugs as a possible cause of rectal stenosis, the history in this particular case suggests that the prolonged use of the cyclooxygenase (COX) inhibitor ’’ibuprofen” as a suppository is the cause of mucosal destruction and rectal stenosis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 0945-053X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1043-4666
    Keywords: IL-1α and IL-1β ; transcription ; translation ; yersinia-infection
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Developmental Biology 148 (1991), S. 562-572 
    ISSN: 0012-1606
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Sedimentology 31 (1984), S. 0 
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: As a result of early Variscan tectonic movements and of differential subsidence, a platform and basin topography was created along the northern margin of the Sahara Craton during the late Devonian. In the Moroccan Anti-Atlas Mountains, the Tafilalt Platform is an approximately N-S running ridge which developed since the late Middle Devonian. It separated a slowly subsiding shallow basin in the east (Tafilalt Basin) from a rapidly subsiding furrow in the west (Mader Basin). Platform deposits are characterized by highly reduced thicknesses, shallow subtidal to supratidal deposits in the late Frasnian and by unconformities at the Lower/Upper Frasnian and the Frasnian/Famennian boundaries. After a local transgression over emergent areas in the north, water depth probably never reached more than several tens to about 100 m in the lower Famennian. Cephalopod limestones of this age, deposited on the platform, represent a very diverse facies pattern comprising quartz-rich brachiopod coquinas, crinoidal limestones, thick-bedded cephalopod limestones and nodular limestones. Sedimentation rates ranged from 1 to 5 mm/ 1000 yr. In the late Famennian more uniform marl and nodular limestone facies suggest slightly deeper environments. Platform margins are characterized by higher rates of subsidence, debris flow deposits and slump structures. In the relatively shallow Tafilalt Basin, marls with intercalated nodular limestones were deposited. In the Mader Basin, sandy and calcareous turbidites suggest deeper water conditions in the late Devonian. During the Strunian/Tournaisian the whole area was overwhelmed by a thick deltaic sequence. The general facies distribution is in agreement with depositional models of other Upper Devonian and Lower Carboniferous cephalopod limestones in the European Variscan orogenic belts. In all these cases, condensed cephalopod limestones occupy a distinct palaeogeographic position in predictable facies sequences that reflect pre-orogenic phases in the Variscan geodynamic cycle. Moreover, close parallels exist with condensed sequences in the Triassic and Jurassic that occur in a very similar position within the Alpine orogenic cycle.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Histopathology 33 (1998), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims: De-differentiated chondrosarcoma is characterized by the presence of two distinct chondroid and nonchondroid tumour portions. The aim of our study was to investigate the distribution of extracellular matrix components in this tumour entity and thus to shed light on its histogenetic origin.〈section xml:id="abs1-1"〉〈title type="main"〉Methods and resultsHistochemical and immunohistochemical analyses were performed for collagen subtypes I, II, III and VI and cartilage proteoglycans in three samples of de-differentiated as well as conventional chondrosarcomas (various grades). In the chondroid tumour areas of de-differentiated chondrosarcoma, typical cartilage matrix components could be detected similar to chondroid areas of grade 1 and 2 conventional chondrosarcomas. In contrast, the tumour matrix of the nonchondroid portions of de-differentiated chondrosarcomas contained matrix molecules which are typical for fibroblastic tissue. This matrix composition was not identical with less differentiated (nonchondroid) areas of grade 2 and 3 conventional chondrosarcomas.〈section xml:id="abs1-2"〉〈title type="main"〉ConclusionsOur results confirm the chondroid nature of the differentiated portion of de-differentiated chondrosarcoma and indicate a nonchondrocytic nature of the nonchondroid portion. De-differentiated chondrosarcoma should not be considered as a ‘de’-differentiated chondrosarcoma (grade 4 neoplasm), but as a tumour entity showing two types of mesenchymal differentiation.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    ISSN: 1432-0827
    Keywords: Key words: Type X collagen — Nondegenerate discs — Scoliotic discs — Endplate — Hypertrophic chondrocyte phenotype — Matrix calcification.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. The distribution and expression of type X collagen, a calcium-binding collagen, which is a marker of hypertrophic chondrocytes and thought to be involved in cartilage calcification, was examined in situ in nondegenerate (grade I or II) human discs taken at autopsy over a wide age range (fetal–〉80 years) and also in scoliotic discs removed at surgery. In the fetal vertebral column, type X collagen was strongly expressed in the hypertrophic chondrocytes of the endplate, but was not seen in other areas. In the cartilaginous endplate of adults, it was found over the whole age range examined, with intensity increasing with age. In the disc matrix itself, type X collagen was demonstrated around individual cells from all individuals older than 50 years, but not in any fetal or autopsy disc from individuals younger than 40 years. In scoliotic discs, however, focal type X collagen expression was seen in 3/8 patients younger than 40 years including one 12-year-old. No type X collagen was found in the outer annulus in any autopsy or scoliotic disc, supporting the idea that cells of the outer annulus are phenotypically distinct from cells of the inner annulus and the nucleus. Our results demonstrate for the first time that type X collagen is a possible gene product of the intervertebral disc cells and a potential biochemical component of the disc matrix. They indicate that with age or in scoliosis, some cells from the inner annulus or nucleus of the disc differentiate to the hypertrophic chondrocyte phenotype. This might be the initiating event for the abnormal calcification described in aged and scoliotic discs in other studies.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1432-1106
    Keywords: Tomography ; Dopamine ; Striatum ; MPTP ; Monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Positron emission tomography following intravenous administration of 6-[18F]-L-fluorodopa was used to investigate the usefulness of PET for the assessment of normal and abnormal dopaminergic function. For this purpose, the incracerebral distribution of 6-[18F]-L-fluorodopa and its metabolites was evaluated in normal control and asymptomatic MPTP-treated rhesus monkeys. MPTP is a neurotoxic compound which destroys selectively the dopaminergic neurons of the nigrostriatal pathways in primates. The 18F accumulation was found to be significantly reduced in the striatum, putamen more than caudate, of the MPTP-treated animals compared to the normal controls. The 18F accumulation in dopamine-poor areas did not differ between the two groups. The ratios of striatum to dopamine-poor brain area were highly correlated to the concentrations of the dopamine metabolite, homovanillic acid, in the cerebrospinal fluid of the same animals. The findings are consistent with the hypothesis that “silent damage” to the dopaminergic nigral neurons may precede the onset of parkinsonism by many years and that PET scanner examination using 6-[18F]-L-fluorodopa may be useful in the detection of subtle dopaminergic dysfunctions as may exist in DA-related motor syndromes and neuropsychiatric disorders.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...