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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 50 (1994), S. 972-974 
    ISSN: 1420-9071
    Keywords: Bengalese finch ; birdsong ; directed song ; undirected song ; maturational process ; fecal steroid hormone ; testosterone dependency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The male Bengalese finch,Lonchura striata, has two types of song behaviour (directed song, DS and undirected song, US). DS and US share a basically identical syllable repertoire, sequence pattern and tempo, but differ in the time course of appearance during the maturational process. In order to examine whether this results from a difference in testosterone (T) dependency, we studied developmental changes in the fecal T level and the amounts of DS and US during the 2–4 month period (N=7). DS appeared between 83 and 94 days of age, 4–16 days after a rise in the fecal T level. In contrast, US appeared earlier and at high frequency even when T was still at a very low level. These results suggest that DS is more dependent on the T level than US, and is not activated until the T level rises during the maturational process.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 41 (1978), S. 257-259 
    ISSN: 1432-0533
    Keywords: Infantile neuroaxonal dystrophy ; Sural nerve biopsy ; Electron microscope ; Schwann cell inclusions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Abnormal Schwann cell inclusion is reported in biopsied peripheral nerve in a cases of infantile neuroaxonal dystrophy. In addition to non-specific dystrophic changes of the axons, the Schwann cells contained several distinct bodies which were composed of stacks of irregularly disposed membranes; in some instances, transformed Schwann cell cytoplasm was distinded with similar bodies. This change has not been reported on this condition and its significance is briefly discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 1450-1451 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The photoreceptor cells in the pineal organ of the Japanese common newt are similar to typical vertebrate photoreceptors. It is supposed that the cells are responsible for the entrainment of locomotor rhythms as a consequence of their response to light.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 108 (1928), S. 554-566 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 75 (1913), S. 29-39 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Wenn man bei Organen, die in Alkohol aufbewahrt waren, ihre Herkunft mit Hilfe der anaphylaktischen Reaktion bestimmen will, so empfiehlt es sich, die Meerschweinchen nicht mit wässerigen Extrakten, sondern mit Aufschwemmungen der Organe vorzubehandeln, da so der Nachweis der Herkunft der Organe noch nach Jahren (in unseren Versuchen bis zu 11 Jahren) gelingt, während bei Verwendung von Extrakten dieser Nachweis schon nach etwa 10 Tagen nicht mehr möglich ist, weil kein Eiweiß mehr in Lösung geht. 2. Man kann mit gewaschenen Hühnerspirochäten echte aktive Anaphylaxie erzeugen. Durch das den Spirochäten trotz gründlichen Waschens noch anhaftende Hühnereiweiß kommt es gleichzeitig zur Ausbildung einer Anaphylaxie gegen Hühnerserumeiweiß. 3. Entgegen den Angaben von Sobernheim u. a. ist es uns leicht gelungen, auch mit Milzbrandbazillen aktive Anaphylaxie zu erzeugen. Ebenso konnten wir durch Vorbehandlung mit B. Paratyphus B und mit B. Friedländer eine starke Anaphylaxie hervorrufen, während wir beim Micrococcus candicans keine deutliche Überempfindlichkeit erzielten.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 170 (1998), S. 132-137 
    ISSN: 1432-072X
    Keywords: Key words Modified meta-cleavage pathway ; 2-Aminophenol degradation ; 2-Amino-2 ; 4-pentadienoic acid ; 2-Oxopent-4-enoic acid ; Pyruvic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A novel pathway for 2-aminophenol metabolism by Pseudomonas sp. AP-3 is proposed. The proposed pathway is similar to that known for meta-cleavage of catechol except that one of the hydroxyl groups on the metabolites is replaced by an amino group. During the degradation of 2-aminophenol, 2-amino-2,4-pentadienoic acid is the last metabolite containing an amino group. We, therefore, propose a modified meta-cleavage pathway for the 2-aminophenol metabolism.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0630
    Keywords: 72.20.Ht ; 72.20JV ; 05.45+b
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Bifurcation routes to chaos in a periodically driven current filament have been studied by computer simulations. By an impact ionization model, theS-shaped currentvoltage curve is perturbed by the dc+ac bias ofE 0+E acsin(27πf 0t). The bifurcation maps are described as a function ofE 0. In the prebreakdown region, the fractal basin boundary, the crisis and the intermittency are discussed, based on the general considerations of the carrier dynamics on the catastrophe manifold. The intermittent burst of the current filament is explained by the destabilization of the weak turbulence generated in the lower branch. In the diffusion-reaction model, the spatio-temporal mode patterns of the transverse carrier profile have revealed the competitive evolution of the hyper-freezing and the firing.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1076
    Keywords: Neonatal screening ; Phenylketonuria ; Maple syrup urine disease ; Homocystinuria ; Galactosemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A nationwide neonatal sreening program for phenylketonuria (PKU), maple syrup urine disease (MSUD), homocystinuria, histidinemia and galactosemia was started in Japan in 1977. The total number of infants screened had reached 6,311,754 by March, 1982. A follow-up study revealed the incidence of the disease in Japan: 1/108,823 for PKU; 1/450,840 for hyperphenylalaninemia (HPA); 1/1,577,939 for biopterin deficiency; 1/525,980 for MSUD; 1/1,051,959 for homocystinuria; 1/8,371 for histidinemia, and 1/788,969 for galactosemia type 1. The incidences of PKU, HPA, homocystinuria, and galactosemia (type 1) were found to be markedly low in Japan as compared with those in Caucasian countries. There was no great difference in the incidence of MSUD between both. On the other hand, the incidence of histidinemia was higher in Japan. It was found that most of the patients with PKU, HPA, MSUD, homocystinuria, or galactosemia are developing normally due to the early initiation of dietary treatment. These results clearly indicate that the neonatal mass screening program plays a great role in preventing the occurrence of handicapped children.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 146 (1987), S. 427-428 
    ISSN: 1432-1076
    Keywords: Lysinuric protein intolerance ; LE cell ; Antinuclear antibodies ; Systemic lupus erythematosus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report an 8-year-old girl with lysimuric protein intolerance and immunological abnormalities including impaired function of lymphocytes, the presence of LE cells, antinuclear antibodies, and hypergammaglobulinaemia. These abnormalities have not been reported before and may be due to an amino acid imbalance or protein malnutrition in cells or tissues. The coincidence of a pre-stage of systemic lupus erythematosus (SLE) and LPI is not excluded.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 23 (1982), S. 197-201 
    ISSN: 1432-1041
    Keywords: nifedipine ; hypertension ; low dose ; plasma concentration ; acute and long-term treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The acute and long-term hypotensive effects of low doses of nifedipine, and the correlation between the fall in the blood pressure (BP) and the plasma nifedipine concentration, were investigated in patients with essential hypertension. The oral administration of nifedipine 5 mg rapidly decreased BP from 163±22/101±10 to 127±12/82±9 mmHg (mean±SD; p〈0.001), and increased heart rate from 72±8 to 76±6 beats/min (p〈0.05), plasma renin activity rose from 1.2±0.6 to 1.4±0.8 ng/ml/h (p〈0.05), and plasma nifedipine concentration was 75.6±22.0 ng/ml 30 min after administration (n=7). The nifedipine concentration was significantly correlated both with the fall in BP (r=0.410, p〈0.02, n=31) and the rise in the heart rate (r=0.412, p〈0.02, n=31). Treatment with nifedipine 5 mg t.d.s. alone or in combination either with propranolol 10 mg t.d.s., or thiazide 1 tablet daily, or propranolol and thiazide, controlled BP in 36 patients during the 22 week study period. During the long-term nifedipine therapy, the plasma nifedipine level was significantly correlated with the fall in systolic (r=0.577, p〈0.01, n=20) and diastolic (r=0.595, p〈0.01, n=20) BP. It was concluded that the plasma nifedipine concentration could be correlated with the fall in BP, and that low doses of nifedipine, either as monotherapy or in combination, were effective in the acute and long-term treatment of patients with essential hypertension.
    Type of Medium: Electronic Resource
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