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  • 1
    Electronic Resource
    Electronic Resource
    Chronic expanding hematoma of the spleen caused by angiomyolipoma in a patient with tuberous sclerosis (1998)
    Springer
    Abdominal imaging 23 (1998), S. 527-530 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Spleen, CT—Spleen, hematomas—Spleen, rupture—Spleen, diseases—Tuberous sclerosis, CT.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We report a case of a chronic expanding hematoma caused by an angiomyolipoma of the spleen in a patient diagnosed with tuberous sclerosis in infancy. Computed tomography showed large bilateral renal angiomyolipomas. A splenic mass that increased in size during the follow-up period of 62 months was also noted. A large subcapsular hematoma of the spleen finally developed, and a splenectomy was performed. The splenic mass consisted of a chronic hematoma with prominent granulation tissue, which was considered to be caused by repeated bleeding from a small angiomyolipoma in the spleen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900392
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  • 2
    Electronic Resource
    Electronic Resource
    ‘Scirrhous’ type hepatocellular carcinomas: a special reference to expression of cytokeratin 7 and hepatocyte paraffin 1 (2005)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 47 (2005), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims : ‘Scirrhous’ hepatocellular carcinoma (scirrhous HCC) is extremely rare and its characteristics remain unclear. We investigated the clinicopathological and immunohistochemical features of scirrhous HCC, compared with those of ordinary hepatocellular carcinoma (ordinary HCC).Methods and results : We compared the clinicopathological and immunohistochemical features of 20 resected cases of scirrhous HCC with those of 69 resected cases of ordinary HCC. Scirrhous HCC was characterized by its gross and histological findings, such as a higher proportion of contiguous multinodular type tumours, the absence of a complete fibrous capsule around the tumour, the absence of tumour necrosis and highly preserved portal tracts in the tumour. The immunohistochemical results revealed a significantly higher expression of cytokeratin 7 and a significantly lower expression of hepatocyte paraffin 1 in scirrhous HCC than in ordinary HCC (P 〈 0.0001, respectively). There were no significant differences in proliferative activity and survival curves between the patients with scirrhous HCC and those with ordinary HCC.Conclusion : Scirrhous HCC has several particular gross, histological and immunohistochemical features. In particular, we would like to emphasize the greater immunohistochemical expression of cytokeratin 7 and lower expression of hepatocyte paraffin 1 in scirrhous HCC than in ordinary HCC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2005.02230.x
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    Paper (German National Licenses)
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