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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 16 (1994), S. 199-204 
    ISSN: 1279-8517
    Keywords: Computed tomography (CT), three-dimensional ; Atlas and Axis ; Spine, anatomy ; Spine, CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Une analyse tridimensionnelle de la rotation atloïdo-axoïdienne est effectuée en tomodensitométrie chez dix sujets sains. La méthode présentée permet une étude des rapports dans l'espace de C1 et C2, en position statique et dynamique, par projection dans un plan transversal fixe. Les résultats mettent en évidence un axe de rotation de C2 légèrement antérieur à celui de C1. Une rotation asymétrique est observée avec une ouverture entre les foramens transversaires de C1 et C2 plus faible du côté controlatéral au sens de rotation de la tête. Cette méthode tomodensitométrique et ces résultats anatomiques peuvent être utilisés dans l'étude de la pathologie de la rotation atloïdo-axoïdienne et de son retentissement sur les artères vertébrales.
    Notes: Summary A three-dimensional analysis of atlantoaxial rotation was made by computed tomography in ten healthy subjects. The method described allowed study of spatial relations between C1 and C2 interspace under both static and dynamic conditions, using a projection in a fixed transverse plane. The results demonstrated an axis of rotation for C2 slightly anterior to that for C1. Asymmetric rotation was observed, the separation between the transverse formaina of C1 and C2 being less marked on the side opposite to the direction of rotation of the head. This use of CT and these anatomic findings may be useful in the study of disorders of atlantoaxial rotation and their effect on the vertebral arteries.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 18 (1996), S. 281-288 
    ISSN: 1279-8517
    Keywords: Linea alba ; Diastasis ; Incisional hernia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La ligne blanche représente la principale voie d'abord en chirurgie abdominale traditionnelle et, par conséquent, le siège le plus fréquent des éventrations abdominales. Le but de ce travail était de réviser sa morphologie et d'étudier ses paramètres mécaniques de résistance, de déformation et d'élasticité, afin de les comparer à ceux des matériaux prothétiques les plus souvent utilisés dans les cures d'éventration. Quarante cadavres frais ont été disséqués, et des tests au dynamomètre et à l'éclatomètre ont été pratiqués sur des échantillons prélevés dans la ligne blanche à trois niveaux: supra-ombilical, infra-ombilical et au niveau de l'ombilic. Quarante scanners abdomino-pelviens ont été analysés. Les résultats morphologiques permettent de définir le diastasis des muscles droits en fonction de l'âge des sujets : en-dessous de 45 ans sera considéré diastatique un écart entre les deux muscles droits supérieur à 10 mm en supra-ombilical, 27 mm au niveau de l'anneau ombilical et 9 mm en infra-ombilical; au-delà de 45 ans les valeurs seront de 15 mm, 27 mm et 14 mm respectivement. Quant à l'étude bio-mécanique, la région infraombilicale présente un coefficient d'élasticité supérieur à celui de la portion supra-ombilicale, mais aucune différence significative de résistance n'a été retrouvée entre les différentes portions étudiées. Les résultats bio-mécaniques sont comparés aux données correspondantes aux matériaux prothétiques.
    Notes: Summary Traditionally, the linea alba represents the principal route of approach in abdominal surgery and in consequence it is the commonest site of incisional hernia. The aim of this study was to review its morphology and to study its mechanical parameters of resistance, deformation and elasticity in order to compare these with the prosthetic materials most often used in the treatment of incisional hernia. Forty fresh cadavers were dissected and tests with a dynamometer and “bursting strength tester” were performed on samples taken from the linea alba at three leveels: supra-umbilical, subumbilical and umbilical. Forty abdomino-pelvic scans were analysed. The morphologic results allowed definition of diastasis of the rectus mm. in terms of subject age: below 45 years of age diastasis was considered as a separation of the two rectus mm. exceeding 10 mm above the umbilicus, 27 mm at the umbilical ring and 9 mm below the umbilicus; above 45 years of age the corresponding values were 15 mm, 27 mm and 14 mm respectively. In the biomechanical study the subumbilical region exhibited a coefficient of elasticity greater than that of the supra-umbilical portion, but no significant difference in resistance was found between the different parts studied. The biomechanical results are compared with the corresponding data for prosthetic materials.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 8 (1998), S. 1009-1113 
    ISSN: 1432-1084
    Keywords: Key words: Wegener's granulomatosis ; Lung diseases ; CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The objective of this study was to assess the reversibility of pulmonary lesions in Wegener's granulomatosis using serial CT. We reviewed the follow-up CT scans of ten treated patients with confirmed Wegener's granulomatosis. The delay between the first evaluation before treatment and the second, on patients in clinical and biological remission, ranged from 6 to 54 months (mean 20.5 months). Follow-up CT showed a decrease in the extent of disease in all cases. Lesions disappeared completely, without scarring, in 4 of 4 ground-glass opacities, 25 of 36 nodules, and 4 of 9 pulmonary consolidations; they disappeared with residual scarring in 8 of 8 masses, 3 of 9 pulmonary consolidations, and 2 of 36 nodules. The majority of lesions disappear without scarring. Residual fibrosis may follow the occurence of masses and pulmonary consolidation. Computed tomography permits assessment of cicatricial lesions.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1041
    Keywords: Diltiazem ; sustained release formulation ; calcium channel blocker ; stable angina ; efficacy ; adverse events
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract The aim of this multicentre randomised double blind study was to compare the efficacy and safety of the 200–300 mg sustained release diltiazem formulation administered once daily (200–300 SR) with standard diltiazem (D) given three or four times daily to patients with stable angina. Patients aged 59 years, with a reproducible exercise test on placebo, were randomised to 4 weeks of treatment with 200–300 SR (n=70) or D (n=74). The initial dosage was 200 mg in the 200–300 SR group and 60 mg t.i.d. in the D group, increased to 300 mg once daily or 60 mg q.i.d., respectively, if ergometric parameters, which were always measured at the end of the dosing period, had not improved after two weeks. After 4 weeks of treatment, the antianginal efficacy at rest was comparable in the 200–300 SR and the D group; there was a prolongation of the total duration of exertion of 14% and 18% respectively (P〈0.01 vs placebo for both groups with no intergroup difference). A dose-effect relation was found with both formulations. The 200–300 SR formulation gave full 24 hour anti-ischaemic protection when administered once daily. Its efficacy and safety were comparable to those of standard diltiazem t.i.d. or q.i.d. in patients with stable angina. The once daily administration should improve treatment compliance.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One hundred consecutive patients were prospectively studied to assess the clinical and biochemical features of symptomatic choledocholithiasis. Biochemical tests were performed during the three days following the onset of symptoms. Pain was the most frequent symptom of choledocholithiasis, observed in 75% of the patients, but rarely occurred alone (12%). Clinical symptoms were not different according to age. High serum gamma glutamyl transpeptidase and alkaline phosphatase were the most frequent biochemical abnormalities in patients with symptomatic choledocholithiasis: they were increased in 94 and 91% of cases, respectively. Only one patient had no biochemical abnormality. Serum transaminases could reach very high levels just as in hepatitis. Biochemical data did not differ regardless of whether the common bile duct was enlarged or not. Biochemical abnormalities had been studied over the first 10 days of spontaneous evolution in 25 patients while choledocholithiasis persisted: serum bilirubin and transaminases significantly decreased while serum gamma glutamyl transpeptidase, alkaline phosphatase, and amylase remained unchanged. These results indicate that, in patients with suggestive symptoms, choledocholithiasis is unlikely in the absence of biochemical abnormalities in the first three days following the onset of symptoms.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Agreement among six physicians for 18 clinical signs in 50 alcoholic patients was prospectively studied. Twenty patients had alcoholic cirrhosis, 14 noncirrhotic alcoholic liver disease, and 16 alcoholics had no clinical or biochemical abnormalities. Agreement was assessed by kappa index for categorical variables and by intraclass correlation coefficient for the others. A good agreement was observed for ascites (r=0.75) and splenomegaly (r=0.75). It was fair for jaundice (r=0.65), Dupuytren's contracture (r=0.65),and vascular spiders (r=0.64). However, it was poor for white nails (r=0.27) and hepatic consistency (r=0.11). Agreement was better among senior physician's than junior physicians. In order to assess which signs contributed to differentiate the three groups of patients, a stepwise discriminant analysis was realized; it identified three variables: vascular spiders (P〈0.001), splenomegaly (P〈0.001), and abdominal wall collateral veins (P〈0.01). These results suggest that studies based on physical findings must be cautiously considered.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 29 (1984), S. 466-469 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A patient who presented with hypercalcemia was found to have an hepatocellular carcinoma. Medical treatment failed to normalize blood calcium levels. Liver resection was not feasible due to major extrahepatic involvement. Selective arterial embolization of the tumor was performed, resulting in correction of the hypercalcemia. This observation suggests that some life-threatening complications of unresectable hepatocellular carcinoma can be treated by arterial embolization of the tumor.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 27 (1982), S. 473-474 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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