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  • 1
    Electronic Resource
    Electronic Resource
    Conjugal septicemia:Salmonella typhimurim (STM) in a couple with AIDS (1986)
    Springer
    Cellular and molecular life sciences 42 (1986), S. 105-106 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01976005
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  • 2
    Electronic Resource
    Electronic Resource
    Zur Häufigkeit des latenten Diabetes in einer jugendlichen Bevölkerungsgruppe (Diagnostik, Methodik und Interpretation) (1974)
    Springer
    Journal of molecular medicine 52 (1974), S. 881-887 
    Details
    ISSN: 1432-1440
    Keywords: Diabetes prevalence ; juvenile diabetes ; diabetes definition ; blood glucose determination ; Diabetes-Prävalenz ; jugendlicher Diabetes ; Diabetes-Definitionen ; Blutzuckerbestimmungsmethoden
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einer jugendlichen schweizerischen Bevölkerungsgruppe wurde die Häufigkeit eines klinisch manifesten und latenten Diabetes mellitus untersucht. Diese betrug 0.06 resp. 1,7%. Die Problematik der Diabetes-Prävalenz in einer definierten Population zeigt sich nicht nur in der Anwendung bestimmter Definitions-Kriterien, sondern auch in der angewandten Methodologie. Es werden die Abweichungen der mittleren Blutzuckerwerte bei simultaner Bestimmung nach sieben verschiedenen Methoden angeführt. Es wird auf fehlende Abhängigkeiten von Alter, Gewicht, Körperoberfläche und biochemischen Parametern (Harnstoff-N, Eiweiß und Cholesterin) sowie vorgängiger Kohlenhydratzufuhr auf den Blutzuckerwert hingewiesen, wenn enzymatische Glucosebestimmungen durchgeführt werden.
    Notes: Summary The prevalence of juvenile diabetes has been examined in a sample of a Swiss population. There was an estimate of 0.06% of clinical and of 1.7% latent diabetes in a group of males of age 20. The problems of assessing diabetes prevalence are discussed in relation to criteria of definition and blood sugar methodology. The differences of seven simultaneous determinations of blood glucose are presented. There was no dependance of fasting blood glucose values in a hospital population in relation to age, weight, body surface and chemical parameters as BUN, total proteins, cholesterol, and the previous intake of carbohydrates as long as an enzymatic glucose determination was performed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468615
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  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of two ELISA tests for the rapid detection of group a Streptococci (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 256-258 
    Details
    ISSN: 1432-1076
    Keywords: Streptococcus pyogenes ; Pharyngitis ; Streptococcal infections, immunology ; Enzyme-linked immunosorbent assay (ELISA)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined 579 oropharyngeal swab specimens from children presenting with pharyngitis in order to compare two rapid diagnostic ELISA tests for group A streptococcal antigen: the TestPack Strep A (TPSA), and the Direct Strep A EIA (DSAE), with an anaerobically incubated sheep blood agar culture. The sensitivities of the methods were respectively 60.8% (TPSA) and 64.4% (DSAE), the specificities 98.3% (TPSA) and 93.2% (DSAE), the positive predictive values 88.6% (TPSA) and 70.3% (DSAE) and the negative predictive values 92.0% (TPSA) and 91.2% (DSAE). We conclude that the TPSA is easy to interpret and is sufficiently specific to initiate treatment in patients with a positive test. It is not sufficiently sensitive to ensure negative or intermediate results. The performance of the DSAE test is similar but the specificity is slightly lower and more false positive results occur.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02106286
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  • 4
    Electronic Resource
    Electronic Resource
    Osteoarticular infections due toKingella kingae in children (1991)
    Springer
    European journal of pediatrics 150 (1991), S. 612-618 
    Details
    ISSN: 1432-1076
    Keywords: Kingella kingae ; Child ; Arthritis infectious ; Osteomyelitis ; Discitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract By the description of two cases of osteoarticular infections due toKingella kingae in two young children we sish to draw the attention of clinicians to invasive infections due to this micro-organism. Since its biological characterization in 1976,K. kingae has been increasingly reported as a human pathogen. Most common presentations are endocarditis, bacteraemia, septic arthritis, osteomyelitis and spondylodiscitis. Interestingly, osteorticular involvement is largely predominant in previously healthy children. From the literature, we reviewed 51 cases ofK. kingae bone and joint infections, representing 23 cases of septic arthritis, 17 of osteomyelitis and 11 spondylodiscitis. Of the cases 88% occurred in children below 5 years of age and in all cases only one bone or joint was involved. An underlying disorder could be found in only 4 patients. Since these infections have a favourable outcome with intravenous antibiotic treatment, proper isolation and identification ofK. kingae is essential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02072618
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  • 5
    Electronic Resource
    Electronic Resource
    Bronchopneumonia and oral health in hospitalized older patients. A pilot study (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 19 (2002), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims: To correlate microbial findings obtained by bronchoalveolar lavage in pneumonia patients with the clinical situation of the oral cavity.Method: Quantitative aerobic and anaerobic cultures were carried out in 150 ml samples of bronchoalveolar lavage (BAL) obtained by means of an endoscope (Video Endoscope Pentax®) inserted per as in the infected bronchus.Material: Twenty consecutive patients with a tentative clinical diagnosis of bronchopneumonia in whom BAL was carried out for diagnostic purposes. A clinical evaluation of the oral health status (oral hygiene, caries, periodontal diseases) was subsequently carried out.Results: In seven edentulous subjects wearing complete dentures the culture of anaerobic microorganisms was negative or yielding less than 100 cfu/ml BAL. Two patients yielded high counts of S. aureus and one high counts of P. aeruginosa. In the 13 subjects with natural teeth left one showed high counts of Veillonella spp. (anaerobic)+P. aeruginosa, one high counts of Veillonella spp. +S. aureus, one high counts of P. aeruginosa + S. aureus and one high counts of E. coli. These four subjects showed poor oral hygiene, periodontal pockets and a BAL microflora consistent with periodontal pathology. Conclusion: The results of this pilot study suggest that microorganisms of denture plaque or associated with periodontal diseases may give rise to aspiration pneumonia in susceptible individuals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2002.00066.x
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  • 6
    Electronic Resource
    Electronic Resource
    Isolation ofMycoplasma hominis on CDC anaerobic blood agar (1996)
    Springer
    European journal of clinical microbiology & infectious diseases 15 (1996), S. 896-897 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01691229
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  • 7
    Electronic Resource
    Electronic Resource
    Comparison of immunological methods for diagnosis of pneumococcal pneumonia in biological fluids (1987)
    Springer
    European journal of clinical microbiology & infectious diseases 6 (1987), S. 28-34 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Five immunological tests were evaluated for their ability to detectStreptococcus pneumonine antigen in serum and urine simultaneously as a means of rapid diagnosis in 40 patients with bacteremic or non-bacteremic pneumococcal pneumonia or pneumonia with other etiologies. Serum and urine were screened in parallel with counterimmunoelectrophoresis (CIE), two commercial latex agglutination kits — the Slidex pneumokit (LA-SPK) and the BactigenStreptococcus pneumoniae kit (LA-Bac) — the coagglutination Phadebact Pneumococcus test (CoA) and a newly developed enzyme-linked immunosorbent assay (ELISA) containing the immunoglobulin G fraction from rabbit pneumococcal antiserum. The detection rate for accumulated serum in bacteremic patients was 18 % for LA-Bac, 24 % for CIE, 47 % for LA-SPK and CoA and 76 % for ELISA, whereas antigenuria was present in only 29 % for LA-SPK, 24 % for CIE, 19 % for CoA, 14 % for LA-Bac and 5 % for ELISA. Detection by ELISA of pneumococcal antigen in severely ill patients can predict bacteremia and rapidly confirm the diagnosis of pneumococcal pneumonia if sputum and results of blood cultures are not available.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02097186
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  • 8
    Electronic Resource
    Electronic Resource
    Serological study of meningococcal isolates in Switzerland and France 1980–1986 (1988)
    Springer
    European journal of clinical microbiology & infectious diseases 7 (1988), S. 788-791 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A study was performed of 342 disease-related strains of meningococci isolated in Switzerland and France between 1980 and 1986, including more than 50% of all strains isolated in Switzerland in 1986. Using a newly developed spot-blot enzyme-linked immunoassay and a panel of monoclonal anti-meningococcal antibodies, 96% of all strains were shown to react with at least one antibody. In both countries more than 50% of the strains were group B. In France serotype 2a was the prevalent serotype and was often associated with subtype P1.2. In Switzerland serological markers of epidemic strains recently described in Northern Europe (serotype 15 and subtype P1.16) were observed with increasing frequency in 1986. However, serotype 4 has been prevalent in Switzerland since 1980 and no clonal population was seen to emerge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01975051
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  • 9
    Electronic Resource
    Electronic Resource
    Serum levels of ciprofloxacin after single oral doses in patients with septicemia (1989)
    Springer
    European journal of clinical microbiology & infectious diseases 8 (1989), S. 1019-1023 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ciprofloxacin serum levels were measured after administration of the drug to 36 patients with septicemia (at least one positive blood culture) who were able to take oral medication. Patients were randomly allocated to receive ciprofloxacin 500 mg p.o. (n=21) or 200 mg i.v. over 30 min (n=15). A first dose was administered 18–30 h after the last positive blood culture (day 1), and a second dose four days later (day 5) in some patients. In addition to ciprofloxacin, standard antibiotics were administered. Organisms isolated wereEscherichia coli (15), other gram-negative bacteria (6),Streptococcus pneumoniae (7),Staphylococcus aureus (2), and other gram-positive bacteria (6). None of the patients vomited. Ciprofloxacin serum concentrations 1 h after oral administration were in the range 0.09–2.32 mg/l, and 2 h after administration in the range 0.5–7.27 mg/l. The average terminal half-life was 8.6 h. In individual patients serum concentrations and area-under-the-curve values were compared. Poor correlation was found between values measured on day 1 and day 5 after oral administration, whereas the correlation was excellent after i.v. administration. Serum levels 2 h after oral administration were 30–900 times the MICs for the gram-negative organisms, but were in the range of the MICs for the gram-positive organisms in some cases. In conclusion, ciprofloxacin serum levels are difficult to predict in septicemia patients after oral administration, but probably suffice to treat infections caused by gram-negative organisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01975162
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  • 10
    Electronic Resource
    Electronic Resource
    Detection ofMycobacterium avium-intracellulare in the blood of HTV-infected patients by a commercial polymerase chain reaction kit (1997)
    Springer
    European journal of clinical microbiology & infectious diseases 16 (1997), S. 549-551 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708245
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