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  • 1
    Electronic Resource
    Electronic Resource
    Reactivity of tris(triphenylphosphine)triruthenium enneacarbonyl (1968)
    s.l. : American Chemical Society
    Inorganic chemistry 7 (1968), S. 1815-1817 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50067a022
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  • 2
    Electronic Resource
    Electronic Resource
    Direct formylation of a methyl group in the oxo reaction. Formation of (R)-3-ethylhexanal in the hydroformylation of (S)(+)-3-methyl-1-hexene (1968)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 90 (1968), S. 6847-6849 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01026a053
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of chlomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat (1995)
    Springer
    Inflammation research 44 (1995), S. 466-469 
    Details
    ISSN: 1420-908X
    Keywords: Chlomipramine ; Fluoxetine ; Edema ; Prostaglandins ; Substance P
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have previously shown that, after acute administration, antidepressant drugs exert anti-inflammatory actions in rats. In this study we evaluated the effects of 3 different doses of chlomipramine (10, 20, and 40 mg/kg i.p), and fluoxetine (5.0, 10, and 20 mg/kg i.p.) on subcutaneous carrageenin-induced inflammation. Both drugs dose-dependently reduced the inflammatory exudate, as well as the PGE2-like bio- and immuno-activity in the exudate. Chlomipramine dose-dependently reduced substance P concentrations in the exudate, whereas fluoxetine was effective only at the highest dose. Our results confirm that antidepressant drugs are able to reduce the development of inflammation in the rat and suggest that the inhibition of substance P production might play a role in mediating the anti-inflammatory effects of chlomipramine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01837911
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  • 4
    Electronic Resource
    Electronic Resource
    Etude des bactéries associées aux Algues marines en culture (1969)
    Springer
    Marine biology 2 (1969), S. 350-355 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé 1. Les auteurs ont isolé quelques souches de bactéries à partir de cultures d'algues marines, et ont essayé d'en préciser le genre et l'espèce. 2. La détermination est basée sur les clefs du Bergey's manual, et sur les publications se rapportant aux espèces décrites dans le milieu marin. 3. Les genres Pseudomonas, Flavobacterium et Achromobacter sont les plus riches en espèces; mais cela ne signifie pas qu'ils dominent effectivement en nombre de germes et en importance métabolique.
    Notes: Abstract Some bacteria strains have been isolated from marine algae cultures and assigned tentative genera and species. Observations and tests were conducted using Bergey's manual and specific papers on marine bacteria as taxonomic keys. The genera Pseudomonas, Flavobacterium and Achromobacter appear to be the most important, as far as the number of species is concerned.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00355715
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  • 5
    Electronic Resource
    Electronic Resource
    Evolution of zinc finger-Y and zinc finger-X genes in oryzomyne-akodontine rodents (Cricetidae) (1992)
    Springer
    Journal of molecular evolution 34 (1992), S. 54-61 
    Details
    ISSN: 1432-1432
    Keywords: Zfy-Zfx genes ; Gene evolution ; Oryzomyne-akodontine rodents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Zinc finger-Y (Zfy) and zinc finger-X (Zfx) genes were analyzed by Southern blotting in male and female specimens of 10 species belonging to the oryzomyne-akodontine stock of Cricetidae rodents. DNA fragments were used as characters to construct a parsimony tree of the genes. Zfx and Zfy trees in general coincide with the evolutionary history of the taxa. Both trees show Oryzomys longicaudatus genes as the outgroup whereas Akodon xanthorrhinus genes are also distant from those of the other species. Oxymycterus rufus and Bolomys obscurus share related sequences, while genes from the other six Akodon species form a group of their own. It was found that 9 out of the 10 species analyzed show Zfy amplification in a range varying from 2 to 24 copies and with a pattern that is clade specific. The estimation of the average changes per character strongly suggests that Zfy has evolved more rapidly than Zfx; our estimates of the rate of nucleotide substitution are 4.6 times higher for Zfy than for Zfx.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00163852
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  • 6
    Electronic Resource
    Electronic Resource
    The pattern of restriction enzyme-induced banding in the chromosomes of chimpanzee, gorilla, and orangutan and its evolutionary significance (1985)
    Springer
    Journal of molecular evolution 22 (1985), S. 323-333 
    Details
    ISSN: 1432-1432
    Keywords: Pongidae ; Chromosome ; Karyotype ; Restriction enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The pattern of banding induced by five restriction enzymes in the chromosome complement of chimpanzee, gorilla, and orangutan is described and compared with that of humans. The G banding pattern induced by Hae III was the only feature common to the four species. Although hominid species show almost complete chromosomal homology, the restriction enzyme C banding pattern differed among the species studied. Hinf I did not induce banding in chimpanzee chromosomes, and Rsa I did not elicit banding in chimpanzee and orangutan chromosomes. Equivalent amounts of similar satellite DNA fractions located in homologous chromosomes from different species or in nonhomologous chromosomes from the same species showed different banding patterns with identical restriction enzymes. The great variability in frequency of restriction sites observed between homologous chromosome regions may have resulted from the divergence of primordial sequences changing the frequency of restriction sites for each species and for each chromosomal pair. A total of 30 patterns of banding were found informative for analysis of the hominid geneaalogical tree. Using the principle of maximum parsimony, our data support a branching order in which the chimpanzee is more closely related to the gorilla than to the human.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02115688
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  • 7
    Electronic Resource
    Electronic Resource
    Axenomycins, new anthelmintic, antiprotozoal and antifungal antibiotics, produced by Streptomyces lisandri nov. sp. (1974)
    Springer
    Archives of microbiology 98 (1974), S. 289-299 
    Details
    ISSN: 1432-072X
    Keywords: Taxonomy ; Streptomyces ; Fermentation ; Antibiotic ; Anthelmintic ; Antiprotozoal ; Antifunga ; Cestocides ; Axenomycins ; Macrolide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract From a soil sample a new microorganism was isolated, described and identified as Streptomyces lisandri nov. sp. In submerged fermentation in a suitable culture medium this streptomycete produces three new related compounds, axenomycins A, B and D. Data on the anthelmintic, antiprotozoal and antifungal activities in vitro are reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00425290
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  • 8
    Electronic Resource
    Electronic Resource
    Depolarization of afferent fibers to the goll and burdach nuclei induced by stimulation of the brain-stem (1968)
    Springer
    Experimental brain research 5 (1968), S. 1-15 
    Details
    ISSN: 1432-1106
    Keywords: Dorsal column nuclei (DCN) ; Primary afferent depolarization (PAD) ; Presynaptic inhibition ; Brain-stem reticular formation ; Centrifugal control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. In nembutalized cats the excitability of superficial radial (SR) and superficial peroneus (SP) primary afferents was tested by microelectrode stimulation (Wall's technique) within the dorsal column nuclei (DCN). SR and SP excitability increased for over 100 msec after conditioning stimulation of the brain-stem with a maximal effect at 50 msec interval. The conditioning curves did not change in decerebrated and cerebellectomized preparations. 2. In nembutalized intact and decerebrated cats a negative slow potential change (over 150 msec) was recorded from one isolated dorsal column (dorsal column potential, DCP) following stimulation of the brain-stem. In the same type of preparations the brain-stem stimulation induced from DCN surface a prolonged (over 150 msec) positive potential (P-wave) which inverted within the nuclei. 3. Interaction experiments have revealed an inhibitory effect of conditioning brain-stem stimulation on SR induced surface P-wave. The effect was maximal at 50 msec interval and was present up to 200 msec. SR stimulation also depressed the brain-stem induced P-wave for over 150 msec but with a maximal effect within the first 20–30 msec. 4. The effects reported above were maximal when the caudal-most brain-stem regions were stimulated. They were still present in control experiments where the sensorimotor cortex had been widely removed 15 days previously.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00239901
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  • 9
    Electronic Resource
    Electronic Resource
    Facilitation of spinal sciatic neuron responses to hindpaw thermal stimulation after formalin injection in rat tail (1999)
    Springer
    Experimental brain research 126 (1999), S. 501-508 
    Details
    ISSN: 1432-1106
    Keywords: Key words Spinal cord ; Wide-dynamic-range neurons ; Tail formalin ; Sciatic afferences ; Thermal stimulation ; Facilitation ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A recent model of formalin injection in the tail induced a facilitation of the hindpaw withdrawal reflexes. In the present work we tried, after injecting formalin into the tail of the albino rat, to determine the spontaneous activity and response changes of lumbar sciatic wide-dynamic-range neurons to thermal stimulations of the paw at 45°C and 48°C (the respective thresholds for noxious and non-noxious thermal stimuli). The experiments were carried out with multiple recording electrodes placed in a comb array in the lumbar segments of the spinal cord at L4–L6 level in the sciatic projection field. A significant facilitation of the spontaneous activity was already evident 2 min after injection; at 5 min there were strong facilitations to the thermal stimuli. Stimuli at 45°C, often ineffective prior to the formalin injection, became strongly excitatory. Stimuli at 48°C evoked more conspicuous responses. This facilitatory effect on spontaneous and thermal responses followed a time-course comparable to that described for the excitations seen after paw formalin injection, but the duration was more prolonged, lasting more than 2 h. These data indicate a facilitatory role of the formalin effects on spinal sciatic neurons after injection in the tail. It is proposed that the mutual effects of spinal neurons in distant spinal segments could explain the facilitation and such a time-course, and that a role in the development of prolonged pain could be envisaged.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002210050758
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  • 10
    Electronic Resource
    Electronic Resource
    On the number of states bound by one-dimensional finite periodic potentials (1995)
    College Park, Md. : American Institute of Physics (AIP)
    Journal of Mathematical Physics 36 (1995), S. 1753-1764 
    Details
    ISSN: 1089-7658
    Source: AIP Digital Archive
    Topics: Mathematics , Physics
    Notes: Bound states and zero-energy resonances of one-dimensional finite periodic potentials are investigated, by means of Levinson's theorem. For finite range potentials supporting no bound states, a lower bound for the (reduced) time delay at threshold is derived. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.531083
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