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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 6 (1927), S. 1090-1091 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 6 (1927), S. 549-551 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 6 (1927), S. 2427-2428 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 8 (1929), S. 1376-1383 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 158 (1934), S. 505-530 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Der Acetonkörpergehalt des Blutes und der Gehalt des Harns an Acetonkörpern ist bei Graviden etwas höher als bei Nichtgraviden. 2. Der Gehalt an Fettsäuren im Blute ist bei Graviden bedeutend höher als bei Nichtgraviden. 3. Nach massiver peroraler Fettbelastung unter Beibehaltung einer gleichen relativ reichlichen Kohlehydraternährung tritt in der Regel eine Vermehrung des Fettsäuren- und Acetonkörpergehaltes im Blute und der Acetonkörper im Harne auf. Diese Reaktion ist bei Graviden ungleich stärker als bei Nichtgraviden. 4. Es wird der Versuch einer Klärung der vorliegenden Untersuchungsergebnisse unternommen unter gleichzeitiger kritischer Auseinandersetzung mit den Befunden und Erklärungsversuchen anderer Autoren.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 155 (1934), S. 443-452 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Es wurde unter Anlehnung an den Gedanken vonGold, der mit Hilfe der Lackmusprobe Schlüsse auf einen erfolgten Blasensprung zu ziehen suchte, und unter Berücksichtigung der bisher vorhandenen wenigen Nachuntersuchungen die Frage geprüft, ob der chemischen Reaktion des Vaginalsekrets zur Diagnose des erfolgten Blasensprungs praktische Bedeutung zukomme. 2. Mit Hilfe des bereits früher benutzten Verfahrens der Foliencolorimetrie wurde zunächst festgestellt, daß intra partum bei noch stehender Blase die pH-Werte im Scheidensekret von 5,2–6,0 schwanken. 3. In der Erwägung, daß bis heute einwandfreie Messungen des Säuregrades der Amnionflüssigkeit nicht vorliegen, wurden mit der gleichen Methode an Ort und Stelle Messungen des Fruchtwassers vorgenommen; es ergaben sich die Werte von 7,0–7,5. 4. Bei gesunden Kreißenden findet sich im Laufe der Geburtnach erfolgtem Blasensprung in der Vagina ein pH-Wert, der mindestens 7,0 beträgt, meistens aber höher ist. 5. Die Foliencolorimetrie, die in den vorliegenden Untersuchungen zur Anwendung kam, und die, wie früher bereits nachgewiesen wurde, einwandfrei arbeitet und gefahrlos anzuwenden ist, wird als klinisches Hilfsmittel empfohlen zur Entscheidung der Frage, ob ein Blasensprung bereits erfolgt sei oder nicht. 6. pH-Werte bis 6,0 beweisen, daß die Fruchtblase noch steht.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 161 (1994), S. 33-46 
    ISSN: 1432-072X
    Keywords: Key words:Methanosarcina barkeri– Pyruvate-utilizing mutant – Methanogenesis – Archaea – Pyruvate fermentation – Acetate fermentation – Growth yields (YCH4) – Ferredoxin – Pyruvate: ferredoxin oxidoreductase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Methanosarcina barkeri strain Fusaro was found to grow on pyruvate as sole carbon and energy source after an incubation period of 10 – 12 weeks in the presence of high pyruvate concentrations (100 mM). Growth studies, cell suspension experiments and enzymatic investigations were performed with pyruvate-utilizing M. barkeri. For comparison acetate-adapted cells of M. barkeri were analyzed. 1. Pyruvate-utilizing M. barkeri grew on pyruvate (100 mM) with an initial doubling time of about 25 h (37 °C, pH 6.5) up to cell densities of about 0.8 g cell dry weight/l. The specific growth rate was linearily dependent on the pyruvate concentration up to 100 mM indicating that pyruvate was taken up by passive diffusion. Only CO2 and CH4 were detected as fermentation products. As calculated from fermentation balances pyruvate was converted to CH4 and CO2 according to following equation: Pyruvate−+H++0.5 H2O→1.25 CH4+1.75 CO2. The molar growth yield (YCH4) was about 14 g dry weight cells/mol CH4. In contrast the growth yield (YCH4) of M. barkeri during growth on acetate (Acetate−+H+→CH4+CO2) was about 3 g/mol CH4. 2. Cell suspensions of pyruvate-grown M. barkeri catalyzed the conversion of pyruvate to CH4, CO2 and H2 (5 – 15 nmol pyruvate consumed/min×mg protein). At low cell concentrations (0.5 mg protein/ml) 1 mol pyruvate was converted to 1 mol CH4, 2 mol CO2 and 1 mol H2. At higher cell concentration less H2 and CO2 and more CH4 were formed due to CH4 formation from H2/CO2. The rate of pyruvate conversion was linearily dependent on the pyruvate concentration up to about 30 mM. Cell suspensions of acetate-grown M. barkeri also catalyzed the conversion of 1 mol pyruvate to 1 mol CH4, 2 mol CO2 and 1 mol H2 at similar rates and with similar affinity for pyruvate as pyruvate-grown cells. 3. Cell extracts of both pyruvate-grown and acetate-grown M. barkeri contained pyruvate: ferredoxin oxidoreductase. The specific activity in pyruvate-grown cells (0.8 U/mg) was 8-fold higher than in acetate-grown cells (0.1 U/mg). Coenzyme F420 was excluded as primary electron acceptor of pyruvate oxidoreductase. Cell extracts of pyruvate-grown M. barkeri contained carbon monoxide dehydrogenase activity and hydrogenase activity catalyzing the reduction by carbon monoxide and hydrogen of both methylviologen and ferredoxin (from Clostridium). This is the first report on growth of a methanogen on pyruvate as sole carbon and energy source, i.e. on a substrate more complex than acetate.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 43 (1992), S. 527-531 
    ISSN: 1432-1041
    Keywords: Calcitonin ; Colonic administration ; Bioavailability ; pharmacokinetics ; pharmacodynamics ; adverse effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Human calcitonin (hCT) injected into the lumen of the descending colon of normal human subjects was absorbed within minutes and could be recognized intact in plasma as shown by RIA in combination with reverse-phase HPLC. The absorption was low and variable, with bioavailabilities ranging from 0.01% to 2.7% relative to intravenously administered hCT (area under the concentrationtime curve). With intravenous hCT serum calcium was lowered and the fractional urinary excretion of calcium, phosphorus, sodium and chloride was significantly stimulated. With the intracolonic hCT, the fractional urinary excretions of calcium, sodium and chloride were also marginally stimulated relative to intracolonic vehicle (placebo). In conclusion, hCT is absorbed intact from the colon, but the bioavailability is low and highly variable.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Trends in Biochemical Sciences 16 (1991), S. 463-467 
    ISSN: 0968-0004
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Physics and Chemistry of Solids 54 (1993), S. 1343-1346 
    ISSN: 0022-3697
    Keywords: Raman spectroscopy ; YBa"2Cu"3O"7 ; critical current ; laser heating
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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