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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 95 (1991), S. 8103-8110 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Psychiatry Research 29 (1989), S. 459 
    ISSN: 0165-1781
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In general, specific immunotherapy with hymenoptera venoms can be considered as safe, but occasionally there are patients who cannot reach the maintenance dose due to repeated systemic reactions (RSR) or who suffer from RSR during maintenance therapy. In a multicenter retrospective study comprising seven departments in Germany, Austria and Switzerland 23 patients with RSR were reported from approximately 3000 patients treated with hymenoptera venoms (bee and wasp venom to approximately equivalent frequency). From these, 22 were allergic to bee venom and only one to vespid venom. In general the clinical symptoms of RSR were milder than the initial reaction. But 4/23 (18%) exhibited cardiovascular reactions up to full shock. Neither anamnestic details, reactivity in skin tests or in vitro tests revealed a special pattern of patients with RSR. In some patients, however, an extremely high reactivity in the skin test was found and may indicate the possibility of further RSR.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 360 (1973), S. 209-222 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Beeinträchtigung der physiologischen Regeneration der Dünndarmschleimhaut durch Bleomycin® wurde röntgenologisch, auflichtmikroskopisch, histologisch und histoautoradiographisch untersucht. Im Gegensatz zu bislang veröffentlichten Untersuchungsergebnissen konnte nachgewiesen werden, daß auch Bleomycin® eine Schädigung der Regenerationszone der Lieberkühnschen Krypten mit konsekutiver Schleimhauttransformation und partieller Zottenatrophie verursachen kann. Dies berechtigt zu der Annahme, daß bei dem relativ „spezifischen“ cytostatischen Wirkungsspektrum (insbesondere auf Plattenepithelien und Plattenepitheltumoren) kein qualitativer, sondern ein quantitativer Wirkungsunterschied bei verschiedener Bleomycin®-Konzentration in verschiedenen Geweben besteht.
    Notes: Summary The alterations in physiological regeneration of mucosa in the small intestine due to Bleomycin® were examined by radiological, histological and histo-autoradiographical methods. In contrast to published results it was possible to prove that Bleomycin® is liable to damage the regeneration region of the crypts with subsequent transformation and partial atrophy of the villous. There is every indication that the relatively specifically cytostatic effect (particularly on squamous cells and squamous-cell tumors) represents not a qualitative but only a quantitative difference from the effect seen in other tissues with different concentrations of Bleomycin®.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Human genetics 〈Berlin〉 73 (1986), S. 39-43 
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Three of six siblings presented with sleep apnea between 18 and 26 months of age. Twin females and a male had normal growth and development without antecedent neurologic or apparent metabolic disorder. The females presented at 25 and 27 months respectively with irregular respiration and episodes of apnea. Twin A succumbed to an apneic episode while sleeping. Central sleep apnea was diagnosed in twin B at the Stanford Sleep Clinic. She died following an apneic episode three months after evaluation. The male presented at 18 months with fatal sleep apnea. A fourth child was evaluated for sleep apnea at 7 weeks of age with several hospitalizations before her death at 31 months. She and remaining family members were extensively studied for inherited neurologic disorders including subacute necrotizing encephalomyopathy (SANE, Leigh disease). This family with lethal sleep apnea presents an association with SANE with minimal neurologic signs and symptoms and neuropathologic involvement. Lesions were conined to the respiratory centers of the lower brain stem, making sleep apnea explicable. This child and family members tested positive or borderline for inhibitor substance thiamine triphosphate (TTP). All testing for TTP inhibitor substance was performed in Professor Jack R. Cooper's laboratory, Department of Pharmacology, Yale University School of Medicine, New Haven, Conn. These cases present an interesting and instructive lesson emphasizing the need for extensive evaluation of children with unsuspected sleep apnea with early demise.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Planta 142 (1978), S. 119-122 
    ISSN: 1432-2048
    Keywords: Chlorophyll ; Ethylene ; Phenylalanine ammonia-lyase ; Phytochrome ; Sinapis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The concept (Burg, 1973) that ethylene mediates the action of phytochrome in seedling photomorphogenesis was tested in the intact mustard (Sinapis alba L.) seedling. The effect of exogenous ethylene (100 μl l−1) on five distinct, phytochrome-mediated photoresponses of the cotyledons was investigated. It was found that anthocyanin contents (see Bühler et al., 1978) and phenylalanine ammonia-lyase levels (EC 4.3.1.5) are strongly reduced by ethylene while the capacity of chlorophyll synthesis is considerably enhanced. Levels of glutathione reductase (EC 1.6.4.2) and pools of photoconvertible protochlorophyll(ide) are unaffected by ethylene. It is concluded that these findings are incompatible with the idea that ethylene plays the role of a mediator in phytochrome-induced photomorphogenesis.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Planta 142 (1978), S. 109-117 
    ISSN: 1432-2048
    Keywords: Anthocyanin synthesis ; Ethylene ; Phytochrome ; Sinapis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The etiolating, intact mustard (Sinapis alba L.) seedling exhibits a distinct temporal pattern of ethylene production. Light, operating through phytochrome, increases the rate of ethylene production without changing the pattern. Ethylene production of the isolated plant parts (segments), added together, exceed the production of the intact system even if the wound effect is taken into account. There is no significant light effect on ethylene production of the segments. Phytochrome-mediated anthocyanin synthesis in the cotyledons is inhibited by ethylene. The responsiveness towards ethylene of the anthocyanin producing metabolic chain is decreased by phytochrome. As anthocyanin synthesis is only partly inhibited under saturating ethylene concentrations in the atmosphere around the seedlings (100 μl l−1), a twofactor analysis becomes feasible. This analysis leads to the result that phytochrome and ethylene show multiplicative behavior, meaning that phytochrome and ethylene act on the same metabolic sequence (leading to anthocyanin) but independently of each other, and at different sites. Therefore, the hypothesis that ethylene mediates the action of phytochrome in anthocyanin synthesis and photomorphogenesis in general appears to be inapplicable.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 320 (1985), S. 71-79 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Rydberg states of the odd-parity series 6p 2(3 p 0)n p of BiI are excited by a three-photon process. A two-photon dissociation of Bi2 into excited atomic states followed by a one-photon absorption leads to highly excited atomic Rydberg states up ton = 32. States of the even-parity Rydberg series 6p 2(3 p 0)nsJ=1/2,ndJ=3/2 andndJ=5/2 are also observed. In order to avoid the background caused by ionization of the bismuth molecules we performed a two-color excitation with pulsed dye lasers. With this experiment the 6p 2(3 p 0)npJ=3/2 Rydberg series could be resolved up ton=75. The increasing quantum defect of this series is due to a perturbing state close to the first ionization limit. By a MQDT analysis we obtain the energy of the perturbing state and a value of 58,761.68±0.1 cm−1 for the first ionization limit of atomic bismuth.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 238 (1968), S. 297-297 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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