Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 10 (1988), S. 0 
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In continuation of previous studies on keratin-substantive sunscreens, two series of quaternary ammonium compounds, derived from 2,4-dihydroxy and from 4-hydroxybenzophenone and containing O-alkyl and N-alkyl chains of different length were prepared and submitted to substantivity tests on wool, to microbiological tests on two bacterial and two fungal species, and to tests for allergenicity/irritation on human skin. All compounds were rapidly adsorbed by wool in aqueous solution: as expected, the maximum amounts adsorbed at equilibrium (Smax), indicative of the skin substantivity, were greatest for the C12 N-alkyl derivatives, and showed a progressive decrease with increasing length of the N-alkyl substituent. No substantial substantivity differences were detected in four C12 quaternary derivatives, differing by the presence (or absence) of a 2-OH group in the benzophenone moiety and by the length of the O-alkyl (n= 2 or 3) side chain. When tested for antimicrobial activity, however, only the 4-hydroxybenzophenone C12 quaternary derivatives showed an order of activity comparable with that of two reference compounds. The conditions leading to a maximal antibacterial activity in the present compounds appeared to be the absence of the 2-OH group, and a shorter O-alkyl side chain. None of the new quaternary derivatives showed skin-irritant properties. The results of this investigation, while confirming the peak substantivity of C12 quaternary derivatives, indicate the possibility of dissociating, in a quaternary ammonium sunscreen, the skin substantivity from other unwanted side-effects, and offer some guidelines for the development of safer agents of this type.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 12 (1990), S. 0 
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The stability of the formaldehyde-releaser preservative Dowicil 200 has been investigated. The studies were carried out on cosmetic emulsions preserved with different concentrations of Dowicil 200, stored in the dark at 45°C or 25°C. The degree of microbiological activity was tested with respect to S. aureus, P. aeruginosa, E. coli and A. niger using the agar diffusion and challenge tests. The chemical stability was evaluated by HPLC in the reverse phase mode. A significant preservative instability was observed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 10 (1988), S. 0 
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The results of a chemical/microbiological comparative study on different preservative mixtures are reported. The aim of the investigation was to ascertain whether there was a correlation between chemical stability and microbiological activity.The studies were carried out directly in cosmetic emulsions preserved with different mixtures of Prevan, Bronopol, Germall 115 and Kathon CG.The degree of microbiological activity was tested with respect to E. coli, Ps. aeruginosa, Asp. niger, S. aureus using the agar diffusion test, over a period of 400 days.The chemical behaviour of the different mixtures was evaluated by HPLC in reverse phase mode. The emulsion samples were directly injected after dilution with a THF/H2O) (9/1) solvent mixture.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1439-0973
    Keywords: Key words Paracoccidioidomycosis ; Therapy of paracoccidioidomycosis ; Mycosis ; Osteolysis ; Itraconazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We describe long-term therapy for paracoccidioidomycosis occurring in a 61-year-old housepainter from Venezuela. The diagnostic examinations made in South America had shown pulmonary granulomatous lesions and an osteolytic pattern of the left knee that had been considered suspect of malignant disease with an indication for limb amputation. With the aid of fine needle aspiration biopsy (FNAB) and culture examination we diagnosed an osteomyelitis by Paracoccidioides brasiliensis and initiated therapy with itraconazole, 400 mg per day reduced to 200 mg per day after 2 months. At the end of 2 years of drug therapy, we observed complete regression of the pulmonary lesions and of the osteolytic area of the left knee. Moreover, we have periodically observed our patient to verify his clinical development and he is still in good health. We suggest that this pathology be considered in differential diagnosis of leprosy, tuberculosis, leishmaniasis, and systemic mycoses, even in non-endemic areas.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1573-7284
    Keywords: HBV infection ; Health care personnel ; Occupational hazard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A prevalence study of HBV serologic markers was carried out among hospital employees of ten departments of the Second School of Medicine in Naples, an urban area with a high prevalence of HBV infection. Departments and occupational categories were selected to represent a spectrum of different exposure to B virus infection. Workers in a large electronic plant in the same geographical area were screened as controls. HBsAg prevalence was 4.8% in the hospital community and 4.0% in control group. It rises to 4.3% in the Campania Region, where all screened workers live, and in some specific areas of the same region it rises to 12%. But no significant difference among seropositivities for at least 1 marker of HBV, considered to be a better indicator of occupational hazard, was found among personnel of different departments or belonging to different occupational categories. None of the occupational and non-occupational risk factors studied was found to be significantly associated with HBV infection. Two years later, an incidence study was carried out among susceptible subjects. Seropositivity for 1 marker was 2.2% among hospital workers and 2.8% in the control group. These figures are lower than the annual attack rate (5%) required for an acceptable cost-benefit ratio of vaccination against hepatitis B. Our results indicate that in a geographical area with HBV endemicity the occupational hazard for B virus infection is low in hospital workers because of the high number of immunized subjects and the contacts with infected people out of the hospital.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1590-3478
    Keywords: Functional MR ; Motor-premotor cortex ; Simple-complex movements
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Scopo di questo studio è stato quello di dimostrare la possibile differenza di attivazione bilaterale per i movimenti delta mano non-dominants nei confronti di quella dominante come pure il diverso coinvolgimento delle aree corticali motorie durante l'esecuzione di movimenti complessi della mano rispetto ai movimenti semplici. È stato utilizzato un apparecchio standard di risonanza magnetica di 1,5 T, per tocalizzare le aree corticali motorie delta mano, utilizzando la tecnica BOLDc ed immagini FLASH a singola sezione. 10 soggetti destrimani sani sono stati utilizzati come volontari per to studio; gli stimoli motori consistevano nell'esecuzione di movimenti semplici (flesso-estensione delle dita) da parte sia delta mano dominante the di quella non dominante, e di movimenti complessi (opposizione delle 4 dita al pollice in maniera ripetuta secondo una sequenza stabilita, 2,4,3,5) da parte delta mano non-dominants. L'esecuzione dei movimenti semplici ha determinato l'attivazione controlaterale dell'area motoria primaria (MA); attivazione ipsilaterale è stata osservata solo per la mano non dominante. Anche l'area supplementare motoria (SMA) è stata attivata, con chiara prevalenza per quella controlaterale. L'entità di attivazione bilaterale delta MA non cambiava con l'esecuzione di movimenti complessi, mentre la SMA, così come l'area premotoria laterale (LPA), erano maggiormente attivate in entrambi i lati con questo tipo di stimolo. In conclusione, la MA ipsilaterale è attivata per movimenti — anche se semplici — eseguiti con la mano non-dominants; esiste una notevole attività funzionale, comprendente la SMA sia controlaterale che ipsilaterale, durante l'esecuzione di movimenti complessi.
    Notes: Abstract The purpose of this study was to show a gradient of possible bilateral activation for movements of the non-dominant vs. dominant hand, as well as for areas involved in complex vs. simple hand movements. A standard 1.5 T magnetic resonance imaging (MRI) system has been utilized to localize the cortical motor hand areas, using the blood oxygen level dependent contrast (BOLDc) technique and single-section fast low-angle shot (FLASH) imaging. Ten normal right-handed subjects volunteered for the study. The motor tasks consisted of simple (flexion-extension) finger movements of either hand, and complex movements (finger-to-thumb opposition in a repeating, pre-planned sequence) of the non-dominant hand. Simple movements caused contralateral activation of the primary motor area (MA); ipsilateral activation was observed for the non-dominant hand only. Supplementary motor area (SMA) was also activated, with a clear contralateral prevalence. The ratio of bilateral activation of MA did not change with complex movements of the non-dominant hand, while SMA as well as lateral premotor area were largely bilaterally activated in this task. In conclusion, the ipsilateral MA is activated for movements — even simple — performed with the non-dominant hand. There is widespread functional activity, involving both contralateral and ipsilateral SMA, for complex movements.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...