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  • 1
    Electronic Resource
    Electronic Resource
    Inhibition of Phosphorylation by Atractyloside (1961)
    [s.l.] : Nature Publishing Group
    Nature 191 (1961), S. 818-819 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Using hypotonically treated rat-liver mitochondria, with reduced diphosphopyridine nucleotide or ferro-cytochrome-c as substrates, inhibition of phosphoryl-ation was observed without decrease in the rate of oxygen uptake3. The 2,4-dinitrophenol-induced adenosine triphosphatase of intact ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/191818a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunogenic changes of murine lymphoma cells following in vitro treatment with aryl-triazene derivatives (1984)
    Springer
    Cancer immunology immunotherapy 16 (1984), S. 157-161 
    Details
    ISSN: 1432-0851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A series of dimethyl aryl-triazene derivatives and related monomethyl compounds were studied for their efficacy in mediating a strong increase in immunogenicity (i.e., chemical xenogenization, CX) of murine leukemic cells following in vitro treatment. It was found that all compounds under investigation were able to induce CX. The dimethyl derivatives were able to induce CX only after metabolic activation, whereas related monomethyl compounds were active per se. The antigenicity acquired by triazene-treated leukemic cells was very marked; intact hosts histocompatible with the parental line were able to reject up to 107 cells. Antigenic tumor cells retained their immunogenic properties even after a large number of transplant generations in the absence of the drug. This means that marked immunogenicity of triazene-treated cells is a stable and heritable characteristic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00205422
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Inhibition by Atractyloside of the Binding of Adenine-nucleotides to Rat-liver Mitochondria (1964)
    [s.l.] : Nature Publishing Group
    Nature 201 (1964), S. 1219-1220 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The experiments described here show that atractyloside, as distinct from other inhibitors of oxidative phosphorylation, is a potent inhibitor of the binding of ATP and ADP to rat-liver mitochondria. The binding of ATP and ADP was tested by addition of freshly prepared mitochondria (isolated in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2011219a0
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    Paper (German National Licenses)
    Fulltext
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