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  • 1
    Electronic Resource
    Electronic Resource
    A NEW TYPE OF ALUMINUM HYDRIDE ADDUCT (1960)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 82 (1960), S. 5506-5506 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01505a051
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  • 2
    Electronic Resource
    Electronic Resource
    GROUND WATER MONITORING FOR TEMIK (ALDICARB) IN FLORIDA (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 25 (1989), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : Over 700 community drinking water supplies were sampled for the pesticide Temik (aldicarb and its oxidative metabolites aldicarb sulfoxide and aldicarb sulfone) in Florida. All community supply wells sampled for Temik were located in counties where Temik was reported to have been used and approximately one-half of the wells were located in counties where ground water was determined to be highly susceptible to contamination by Temik. Susceptibility was determined using ranking criteria that incorporated ground water recharge characteristics, water use, and Temik use patterns.Temik was not detected in any of the community supply wells sampled during the study. However, Temik was detected in shallow, private wells, as was the pesticide ethylene dibromide in counties with ground water characterized as highly susceptible to contamination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.1989.tb05668.x
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  • 3
    Electronic Resource
    Electronic Resource
    Potash from Polyhalite Relation between calcinations conditions and extraction behavior (1937)
    s.l. : American Chemical Society
    Industrial & engineering chemistry 29 (1937), S. 475-482 
    Details
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ie50328a027
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  • 4
    Electronic Resource
    Electronic Resource
    071
TGF-ß-Mediated Paracrine Regulation of Keratinocyte Wound Closure (2004)
    Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc.
    Wound repair and regeneration 12 (2004), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The importance of stromal-epithelial interactions in wound healing is well established. These interactions likely involve autocrine and paracrine action of multiple growth factors, including members of the TGF-ß family. TGF-ß1, ß2 and ß3 isoforms signal by sequentially binding to the TGF-ß type II and type I receptors, respectively. We address the role of TGF-ß signaling in dermal fibroblasts using a conditional fibroblastic TGF-ß type II receptor knockout mouse model (termed FßKO). We found that the loss of TGF-ß signaling in the dermal fibroblasts results in accelerated excision-wound closure compared with similar wounds in wild type mice. The mechanism of the altered rate of re-epitheliaization in the FßKO mice was examined with regard to keratiocyte motility and proliferation. The migration of keratinocytes through collagen I coated 8 μm pore filters in the presence or absence of fibroblast-conditioned media was tested. These experiments showed increased keratinocyte migration when incubated with FßKO dermal fibroblast conditioned media compared to media conditioned in wild type fibroblasts. Immuno-histochemical staining of paraffin embedded intact skin indicated both wild type and FßKO mice had similar low levels of keratinocyte proliferation, based on Ki67 staining. In healing wounds, only the distal wound edges of wild type mice were proliferative. In contrast, the FßKO mice exhibited elevated proliferation across the length of the wound, including the leading edge of epithelial closure. Together our results suggest TGF-ß signaling by the dermal fibroblasts suppresses re-epithelialization of excision wounds by regulating keratinocyte motility and proliferation through paracrine mechanisms. 
 Funding: DOD BC99184 and NIH CA85492.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1067-1927.2004.0abstractbr.x
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  • 5
    Electronic Resource
    Electronic Resource
    089
Tensile Strength Deficiency in Skin and Wounds Of Substance P Receptor (NK1R) Knockout Mice (2004)
    Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc.
    Wound repair and regeneration 12 (2004), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Diabetic neuropathy leads to reduced innervation that may in turn diminish the availability of tachykinins such as Substance P (SP). In diabetic mice, exogenous SP has positive effects on wound closure. The role of SP was tested by inactivating the murine SP receptor gene (neurokinin-1 receptor, NK1R). Age-matched, NK1R-/- mice and C57/BL6 control mice were each given 2 full thickness 6 mm excisional wounds on their dorsal surface and creation of two dead space wounds by the insertion of two 1 × 3 mm PVA sponge disks under the skin through a 1.5 cm long ventral midline incision. Digital images for wound closure analysis were collected until day 10 when tissues were harvested for biochemical, histological and tensiometric analysis.There was a striking reduction (2.5 fold, p 〈 0.05) in the tensile strength of intact, unwounded skin of the NK1R-/- mice, and tensile strength of 10 day incisions was likewise reduced (1.8 fold, p 〈 0.0126). Wound closure rates were also reduced in the knockout mice, but not to a significant level. Sponge granulation tissue had equivalent protein and DNA content at 10 day post-implantation while collagen content was diminished. Histological examination of excisions, normal skin and sponges showed no readily observable difference in thickness or organization however NK1R-/- mice exhibited visibly less collagen in excisional wounds. The principal dermal effect seen in this gene deletion appears to be the accumulation and organization of connective tissue. Our preliminary results with a non-diabetic NK1R-/- mouse do not indicate a marked difference in reëpithelization, but instead a significant decrease in biomechanics. The parallel diminution of intact skin and wound strength suggests an intrinsic defect in collagen fiber maturation that may be reflected in ultrastructural organization or covalent crosslinking.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1067-1927.2004.0abstractch.x
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  • 6
    Electronic Resource
    Electronic Resource
    DAY-TO-DAY VARIATIONS IN FASTING PLASMA GLUCOSE AND FASTING PLASMA INSULIN LEVELS IN LATE NORMAL PREGNANCY (1974)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 81 (1974), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The fasting plasma glucose and fasting plasma insulin levels of eight normal outpatient primigravidae have been studied over six successive days at 37 weeks' gestation. In addition, the fasting plasma glucose in six primigravidae, who were in-patients in a metabolic unit, has been measured on three successive days. It is concluded that while there is in general little day-to-day variation in both fasting plasma glucose and fasting plasma insulin, the plasma glucose was significantly elevated on the first day of the study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1974.tb00527.x
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  • 7
    Electronic Resource
    Electronic Resource
    Endocrine Regulation of Behavior (1972)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Physiology 34 (1972), S. 375-408 
    Details
    ISSN: 0066-4278
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ph.34.030172.002111
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  • 8
    Electronic Resource
    Electronic Resource
    Rapid Volumetric Method for Determination of Potassium (1931)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 3 (1931), S. 324-325 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac50075a043
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  • 9
    Electronic Resource
    Electronic Resource
    Adhesion formation is reduced after laparoscopic surgery (1999)
    Springer
    Surgical endoscopy and other interventional techniques 13 (1999), S. 10-13 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Adhesions (formation, grade, vascularity) — Laparoscopy — Tissue trauma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Adhesion formation after abdominal operations causes significant morbidity. Methods: Adhesion formation in pigs was compared after placement of prosthetic mesh during celiotomy (group 1), laparoscopy with large incision (group 2), and laparoscopy (group 3). After peritoneum was excised, polypropylene mesh was fixed to the abdominal wall, then to the opposite abdominal wall in the preperitoneal space followed by peritoneal closure. Adhesion area, grade, and vascularity were measured. Results: More adhesions (p 〈 0.02) covered intraperitoneal mesh (7.57 ± 1.89 cm2) than covered reperitonealized mesh (2.16 ± 1.13 cm2), and adhesion grade was significantly greater (p 〈 0.02). Adhesion areas were significantly greater in groups 1 and 2 than in group 3 (p= 0.001 and 0.03, respectively). Adhesion grade was significantly greater in groups 1 and 2 than in group 3 (p= 0.02 and p= 0.04, respectively). Groups 1 and 2 had more vascular adhesions than group 3 (p 〈 0.01 and p= 0.02, respectively) Conclusions: A foreign body within the peritoneum stimulates more numerous and denser adhesions. Tissue trauma distant from the site of adhesions increases their formation. A major advantage of laparoscopic surgery is decreased adhesion formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900887
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  • 10
    Electronic Resource
    Electronic Resource
    Animal models for wound repair (1998)
    Springer
    Archives of dermatological research 290 (1998), S. S1 
    Details
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Progress in wound pharmacology is dependent on the availability of suitable animal wound models. All animal models try to reflect human wound healing problems. In acute models it is easier to achieve approximations to the clinical situation than in models for the chronic wound.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00007448
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