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  • 1
    ISSN: 1432-0568
    Keywords: Cat caudate nucleus ; Ischemia ; Plasmalemmal glial assemblies ; Cytotoxic edema
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Selective cerebral ischemia was induced in the caudate nucleus of seven normothermic anesthetized cats through transorbital clamping of the anterolateral penetrating lenticulostriated arteries. The plasmalemma of astrocytic foot processes has been studied with the freeze-fracture technique and conventional electron microscopy 10, 15 and 30 min after ischemia. After 15 min of circulatory arrest, assemblies of intramembrane particles (IMPs) disappear in some areas of astroglial perivascular plasmalemma in the ischemic caudate nucleus. Interastrocytic gap junctions do not change significantly. 30 min after ischemia, the pericapillary astroglial end foot is expanded and organelles are greatly perturbed (cytotoxic edema). Although the function of astrocytic intramembrane particle assemblies is unclear, it is postulated that the disappearance of this membrane specialization may play a role in the pathophysiology of cytotoxic astroglial edema.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 37 (1981), S. 775-777 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary On the 8th post-operative day, an endothelial layer covers the ‘venous patch’ luminal part when the adventitia of the patch is sutured to a 5–8 mm-long arteriotomy performed in the common carotid of the rat. The probable origin of this secondary endothelium is discussed.
    Type of Medium: Electronic Resource
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