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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 242 (1995), S. 180-181 
    ISSN: 1432-1459
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 237 (1988), S. 184-187 
    ISSN: 1433-8491
    Keywords: Non-traumatic coma ; Somatosensory-evoked potential ; Motor-evoked potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A total of 28 patients with non-traumatic coma were studied both with somatosensory- and motor-evoked potentials. While somatosensory-evoked potentials (SEP) have proved to be useful in predicting the outcome in patients with severe brain damage, the aim of this study was to find out whether the additional evaluation of motor-evoked potentials (MEP) could contribute to a better prediction of the outcome than SEP alone. Our results clearly indicate that in terms of prognostic value, SEP are superior to MEP. Nine patients with bilaterally preserved MEP died, while all of the patients with bilaterally preserved SEP and a central conduction time ≤ 6.5 ms survived, with a Glasgow outcome score of 1 to 3. Therefore, we cannot recommend the inclusion of MEP in the prognostic evaluation of patients with non-traumatic coma.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 226 (1981), S. 85-99 
    ISSN: 1432-1459
    Keywords: Hereditary pressure-sensitive neuropathy ; Auditory ; Somatosensory-evoked potentials ; Motor, sensory nerve conduction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Sieben Mitglieder einer Familie mit hereditärer druckempfindlicher Neuropathie wurden klinisch und elektrophysiologisch untersucht. Im Suralis-Bioptat des Propositus, der sich wegen einer inkompletten Armplexusparese vorstellte, zeigten sich die charakteristischen tomaculären (wurstförmigen) Myelinverdickungen als Hinweis auf eine gestörte Axon-Myelin-Relation. Bei den vier Familienmitgliedern mit den klinischen Zeichen der Erkrankung fanden sich verlangsamte motorische und sensible Leitgeschwindigkeiten an verschiedenen Nerven. Zusätzlich wurde die zentrale Leitungszeit in auditiven und somatosensorischen Bahnen bestimmt, wobei die Latenzdifferenzen von Welle I–V im akustisch evozierten Hirnstammpotential und von Peak N14–N20 in Medianus-SEP berechnet wurden. Die zentralen Leitungszeiten in beiden Systemen lagen im Normbereich. Die absolute Verzögerung von N14 und N20 in Medianus- sowie P40 in Tibialis-SEP ist wahrscheinlich Folge einer verlangsamten Leitung im peripheren Ast der bipolaren Ganglienzelle. Ob auch eine Affektion des zentralen Axonastes in den Hintersträngen vorliegt, kann anhand der Resultate dieser Arbeit nicht entschieden werden.
    Notes: Summary Seven members of a family with histologically proven hereditary pressure-sensitive neuropathy (HPSN) agreed to be examined clinically and electrophysiologically. A sural nerve biopsy specimen taken from the propositus who suffered from a partial brachial plexus palsy showed typical ‘sausage-like’ myelin sheath thickenings reflecting a failure of axon-adjusted myelination. Reduced motor and sensory conduction velocities involving several nerves were found in the four family members with clinical signs of HPSN. In addition, central conduction times in the auditory and somatosensory pathways were determined measuring the interwave latency I–V in brainstem auditory-evoked potentials and the interpeak latency N14–N20 in median nerve sensory-evoked potentials. Central conduction times in both afferent systems were within normal limits. The absolute delay of peak N14 and N20 in median and P40 in tibial nerve-evoked potentials was probably due to an impaired conduction in the peripheral branch of the bipolar ganglion cell. Whether the central axon branch in the dorsal columns was also involved could not be decided.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1459
    Keywords: Key words Temporal lobe epilepsy ; Hippocampus ; Magnetic resonance imaging ; Fluoro-2-deoxy-d-glucose positron-emission tomography ; Wada test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In refractory temporal lobe epilepsy (TLE) temporal lobe structures and functions are continuously or intermittently affected by abnormal brain electrical events, noxious neurochemical agents, and metabolic disturbances. There is conflicting evidence regarding the relationship between the duration of refractory mesial TLE and quantitative measures of temporal lobe functions and volumes of the hippocampi. Twenty patients (aged 28 ± 7 years, 14 males) with an initial precipitating injury before the age of 5 years were subjected to high-resolution magnetic resonance imaging, fluoro-2-deoxy-d-glucose positron-emission tomography (PET), and the Wada test. We investigated whether the duration of unilateral refractory TLE (12 left, 8 right) affects hippocampal volume, glucose metabolism, or Wada hemispheric memory performance. Ipsilateral to the epileptogenic zone the hippocampal volume, metabolism, and Wada hemispheric memory performance were reduced compared to the corresponding contralateral measures. The duration of epilepsy controlled for age at investigation, side of seizure origin, underlying cause, and sex were negatively correlated with ipsi- and contralateral hippocampal volume, hippocampal metabolism, and Wada hemispheric memory performance. Moreover, ipsilateral Wada hemispheric memory performance and contralateral hippocampal glucose metabolism were correlated with the frequency of habitual seizures. Refractory TLE seems to be associated with a slow but ongoing bilateral temporal lobe damage. These cross-sectional results require verification by longitudinal studies carried out over a period of more than two decades.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neurosurgical review 15 (1992), S. 61-64 
    ISSN: 1437-2320
    Keywords: Carotidal dissection ; Doppler sonography ; magnetic resonance tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Whereas previously the dissection of arteries leading to the brain was thought to be a rare occurence, this diagnosis has been found more frequently in the last years as a result of newer imaging methods. Furthermore, in contrast to earlier opinions, there is a rather good prognosis for the recanalisation of the vessels and the restoration of the patient's health. In this paper, three cases with nearly typical constellation of symptoms and beneficial outcome are demonstrated. The related Doppler sonographical findings including duplex scan as well as the angiographical, computer tomographical and magnetic resonance tomography results are reported. It is to be noted that none of the three patients had a severe trauma or belonged to typical risk groups for a spontaneous dissection (Marfan's Syndrome, fibromuscular dysplasia).
    Type of Medium: Electronic Resource
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