ISSN:
1432-0533
Keywords:
Skeletal Muscle
;
Tissue Culture
;
Virus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In chick skeletal muscle fibers cultured from embryos of commercially obtained “normal” eggs we have demonstrated numerous C-particles and large amounts of avian leucosis/sarcoma envelope antigen, especially when cultured in the presence of dinitrophenol. C-particles were present in t-tubules, which were possible intracellular viaducts of infection or dissemination and perhaps were the loci of receptors of viral invasion of the cytoplasm and sites of egress. The abundant lace-like membraneous proliferations, probably of t-tubules, usually had C-particles adjacent to or within them and perhaps were virus-provoked. Questioned is the validity of using cultured muscle, or extract, of embryos from ordinary chicken eggs for analysing normal biological phenomena—or conversely, is viral influence “normal” in chick development?
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00696789
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