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  • 1
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage (SAH) ; intracranial aneurysm ; vasospasm ; cerebral metabolism ; cerebral circulation time
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective study of cerebral angiographies from 173 patients with subarachnoid haemorrhage (SAH) were investigated and divided into three groups. The diameters of the middle cerebral artery and the internal carotid artery were measured and correlated with time elapsing between the onset of SAH and the angiographic study. A significant (p〈0.001) reduction in vascular diameter was found at all levels of intraas well as extradural parts of the internal carotid artery in patients with aneurysms (group I). Also, bilateral angiographic investigation from 70 patients showed a significant (p〈0.001) reduction at all levels on both sides, regardless of whether aneurysms were present (group II) or not (group III). Moreover, the reduction in vascular diameter was more pronounced in patients with than in patients without aneurysms. The most pronounced reduction in vascular diameter was found in one of the extradural parts of the internal carotid artery in both group II and III. However, reduction in vascular diamter did not correlate significantly with the cerebral circulation time despite a tendency towards it. On the other hand, layering of the contrast medium along the posterior wall of the internal carotid artery was more often found in patients with prolongation in cerebral circulation time suggesting a reduced cerebral blood flow in these patients. It is suggested that the significant reduction in vascular diameter of intra-as well as extradural parts of the internal carotid artery, might reflect an adaptation to altered cerebral metabolism after SAH.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 97 (1989), S. 146-149 
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage (SAH) ; blood brain barrier (BBB) ; positron emission tomography (PET)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 26 patients with subarachnoid haemorrhage (SAH) were investigated with 68-Ga-EDTA and positron emission tomography (PET) in order to evaluate the presence of a blood brain barrier (BBB) disturbance. Only one patient showed a BBB disruption. It is suggested that increased levels of substances with higher molecular weight than 68-Ga-EDTA in the cerebrospinal fluid (CSF) are the result of a change in the metabolism of the CSF and the brain tissue caused by a SAH.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 98 (1989), S. 164-166 
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage (SAH) ; glycosaminoglycans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixteen patients dying after subarachnoid haemorrhage (SAH) were investigated with regard to the presence of angiographic vasoconstriction and of glycosaminoglycans in samples from the main cerebral arteries. All patients had a statistically significant (p 〈 0.001) vasoconstriction at angiography performed before death. At morphological examination, the vessels of all patients showed signs of intimai thickening, necrosis of the media and leucocyte infiltration of the adventitia. The presence of glycosaminoglycans was determined semiquantitatively and did not differ from the values obtained from presumably normal controls. It is suggested that the angiographically verified vasoconstriction found after SAH as well as the morphological changes of the cerebral arteries are not related to a concentration increase of glycosaminoglycans.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0942-0940
    Keywords: Arterio-venous shunt ; bleeding course ; epidural haematoma ; diploicveins ; absorption capacity ; epidural space ; subarachnoid space ; clinical outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to test the possibility suggested in previous studies that the long bleeding time and the large bleeding volume observed in experimental epidural bleeding can be explained by the development of an arterio-venous shunt, water soluble X-ray contrast was injected into the epidural space in dogs during an epidural bleeding in progress. It was found that the contrast medium left the epidural space through diploic veins in the cranial bone to the neck veins. By draining off epidural blood the arterio-venous shunt counteracts the intracranial pressure tamponade developing in intradural bleeds and thus prolongs bleeding. Perfusion experiments showed the absorption capacity for saline to be about 20 times as large in the epidural space as in the CSF space. While there was no apparent absorption limit for blood in the epidural space the absorption capacity for blood of the subarachnoid space became progressively saturated, leading to a continuously increasing CSF outflow resistance and CSF steady-state pressure. A theory for the formation of epidural haematoma is proposed which in essence implies that the epidural shunt is a major determinant of the clinical outcome of an epidural bleeding.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0942-0940
    Keywords: Arteriovenous malformation (AVM) ; subarachnoid haemorrhage (SAH) ; cerebral arterial vasospasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifty (50) selected patients with arteriovenous malformation (AVM) with and without subarachnoid haemorrhage (SAH) were investigated, in respect of occurrence and course of the vasospasm. The diameters of the carotid siphon and its main branches were measured and plotted against the time elapsing between the haemorrhage and the angiographic study. Patients without SAH were used as a reference group. The results suggest intracranial arterial spasm to occur between the third and eleventh day after the onset of SAH. Patients with intracerebral haematoma may show vasospasm from the first day onwards. It seems that the radiologically demonstrated spasm in AVM had no impact on the clinical outcome in this series.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 121 (1993), S. 212-215 
    ISSN: 0942-0940
    Keywords: Cerebral arteriovenous malformation ; radiosurgery ; risk of further haemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case with an ill-defined arteriovenous malformation in the parieto-occipital region is presented. Open surgery was unsuccessful in removing the AVM totally, and treatment with gamma knife radiosurgery was then attempted. At 14 months after this treatment the AVM was believed to be obliterated. The patient had a new intracranial haemorrhage 59 months after radiosurgery. Renewed angiography showed an obvious AVM outside the previously irradiated area. Retrospective analysis of the angiogram at 14 months after radiosurgery revealed early filling of a draining vein as a sign of residual AVM at this time. Renewed radiosurgical treatment was performed. It is believed that an ill-defined margin, laminar flow, and effects of previous surgery might add to difficulties in a proper visualisation and delineation of an AVM. Further, a small remaining shunt may be overlooked if the angiogram is not carefully analysed or if the angiogram is of inferior quality. It should be stressed that partial or almost total obliteration of an AVM is no protection against rebleeding.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 40 (1978), S. 145-149 
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two cases with broken aneurysm-clips are presented.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 38 (1976), S. 128-129 
    ISSN: 0165-1161
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 38 (1987), S. 729-734 
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Livestock Production Science 20 (1988), S. 175-192 
    ISSN: 0301-6226
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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