Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Analytical Biochemistry 186 (1990), S. 229-232 
    ISSN: 0003-2697
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 51 (1993), S. 73-99 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary We examine a family of tall (up to 20 km) cumulonimbus complexes that develop almost daily over an adjacent pair of flat islands in the Maritime Continent region north of Darwin, Australia, and that are known locally as “Hectors”. Nine cases observed by a rawinsonde network, surface observations (including radiation and soil measurements), the TRMM/TOGA radar, and one day of aircraft photography are used to analyse the development, rainfall, surface energy budgets, and vertical structure of these convective systems. The systems undergo convective merging which is similar to that observed in previous Florida studies and is multiplicative in terms of rainfall. About 90% of the total rainfall comes from the merged systems, which comprise less than 10% of convective systems, and this has implications for the manner in which tropical rainfall is parameterised in largerscale numerical models. By comparison to the West Indies, GATE, and Florida, the Hector environment contains a weaker basic flow, with less vertical shear. The main thermodynamic difference is that the Darwin area has an unstable upper troposphere and very high tropopause. Numerical modelling results support earlier observations of updraughts in excess of 30 ms−1 in this region, but show that only modest convective drafts are experienced below the freezing level (5 km). The surface fluxes over the islands are estimated from a Monash University study to be mainly in latent form from evapotranspiration, with a Bowen ratio only slightly larger than that commonly observed over oceans. These surface fluxes are crucial to the development of a suitable mixed layer to support deep convection. The flux estimates agree with the observed changes below the cloud base and provide sufficient information for calculations of the bounds on precipitation efficiency. Of particular interest are the observations of Hector development on a day when the islands were under a dense cirrus overcast. We find that the islands still provide sufficient net sensible and latent heat fluxes to initiate convection.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The probabilistic approach to tropical cyclogenesis is advanced here by examining the role of convection in the early stages. The development of “hot towers”, that is tall cumulonimbus towers which reach or penetrate the tropopause, and their role in tropical cyclogenesis is investigated in two well-documented cases of formation. namely hurricane Daisy (1958) in the Atlantic and Tropical Cyclone Oliver (1993) in the Coral Sea. The hot towers in Daisy had been intensively studied by Malkus and Riehl three decades ago but remained mainly unpublished. The dynamics of Oliver genesis by merging mesoscale vortices has been recently reported, but much of the aircraft data remained. This paper adds the evolving contribution of cumulus-scale events and their associated electrification, which was made possible by the addition of an electric field mill, a numerical cloud model and other remote sensors. In their genesis stages, Daisy and Oliver appeared very different because Daisy resulted from a deepening tropical wave in the Atlantic and the pre-Oliver vortex emerged eastward from the Australian monsoon trough. However, the vertical profiles of θE in the rain areas were nearly identical, with the characteristic concave shape showing substantial midlevel minima. Therefore, both required increasing upflux of high θE subcloud air in order to accomplish the formation stage, with about two hot towers each in the nascent eyewall. In both cases, partial eyewalls developed at the edge of the convection, permitting subsidence in the forming eye, which was shown to contribute to the pressure fall. The probabilistic concept proposes that any contribution to early pressure fall raises the probability of success. When the incipient storm goes through those fragile phases more rapidly, the risk of death by the onset of unfavorable large-scale factors such as wind shear or upper-level subsidence is reduced. Daisy developed in an inactive, moist environment with light, variable winds throughout the troposphere while in Oliver, strong divergent upper outflow apparently outweighed strong wind shear, although the latter was responsible for a slow and messy development of a closed, circular eye. In both storms, the hot towers in the major rainband were taller and stronger than those in the early eyewall. Onedimensional time-dependent model runs were used to simulate both in Oliver with two important results: 1) the taller rainband clouds permitted greater high level heating, if it could be retained; and 2) greater electrification and more lighting occurred in the rainband although the partial eyewall clouds also showed strong electrification. Airborne radar, electrification measurements and models are fitted together to understand their relationship. An important result is the clear inference that fairly deep mixed phase regions existed in both eyewall and rainband, in which the DC-8 aircraft experienced liquid water at temperatures colder than −40°C below freezing. These results show that the claims of no supercooled liquid water in tropical cyclones require re-examination with the proper measurements of electricification that are now feasible.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 53 (1994), S. 185-222 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The evaluation of a maritime continent thunderstorm complex (Hector) occurring over Bathurst and Melville Islands north of Darwin, Australia (12° S, 131° E) is investigated primarily using Doppler radar data. Thunderstorm formation follows the development of sea breeze circulations and a period of shallow non-precipitating convection. Evidence exists for initiation of long-lived and organised convection on the sea breeze fronts, although short-lived, scattered convection is apparent earlier in the day. Merging of the convective systems is observed in regions of enhanced low-level convergence related to sea breeze circulations. The merged convective complex is initially aligned in an almost east-west direction consistent with the low-level forcing. The merged complex results in rapid vertical development with updraughts reaching 40 m s− and echo tops reaching 20 km height. Maximum precipitation production occurs during this merger phase. On the perimeter of the merged convective complex, evidence exists for front-to-rear updraughts sloped over lower-level downdraughts with rear-to-front relative flow and forward propagating cold pools. The mature phase is dominated by this convection and the complex re-orientates in the prevailing easterly vertical shear to an approximate north-south direction, then moves westward off the islands with the classic multicellular squall-like structure. The one-dimensional cloud model of Ferrier and Houze (1989) used with a four class ice formulation reproduced the cloud top height, updraught structure and echo profile very well. To test the importance of ice physics upon thunderstorm development, several sensitivity tests were made removing the effects of the ice phase. All of these model clouds reached nearly 20 km, although simulations without the effects of ice had updraughts reduced from about 40 m s−1 to 30 m s−1. The simulated convection was more sensitive to changes in environmental conditions and parameterised cloud dynamics. The strong intensity of the convection was largely accounted for by increasing equivalent potential temperatures due to diurnal heating of the surface layer. The vertical velocity and radar structure of the island thunderstorm has more similarity with continental rather than oceanic convection. Maximum vertical velocities, in particular are almost an order of magnitude greater than typical of oceanic convection. With the intense updraughts, even in the low shear environment, there is evidence for mesoscale circulations within the convection.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 413 (1989), S. 217-224 
    ISSN: 1432-2013
    Keywords: Rat ; Kidney ; Uptake ; Transport ; α-Ketoglutarate ; Luminal ; Basolateral ; Production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to establish the characteristics of net renal transport and utilization of α-ketoglutarate (α-KG) in the rat, we have precisely quantified the renal blood flow, the urinary flow and the rates of α-KG delivery, filtration, reabsorption or secretion, excretion, uptake or production by an in vivo rat kidney preparation. In normal rats, α-KG uptake was higher than α-KG reabsorption at both endogenous and elevated plasma α-KG concentrations; thus, a net peritubular transport, which was the main supplier of α-KG to the renal cells, took place. Saturation of reabsorption and peritubular transport of α-KG occurred at blood α-KG concentrations about 30 and 150 times above normal, respectively. Acute metabolic acidosis was found to have no effect on renal handling of α-KG. At endogenous plasma α-KG concentrations, alkalosis converted net renal uptake into net renal production of α-KG resulting in addition of α-KG by the renal cells both to blood and to the luminal fluid. Elevation of blood α-KG concentration restored the renal uptake of α-KG. This uptake, which was entirely accounted for by the peritubular transport of α-KG, reached a maximum which was lower than that observed in normal and acidotic rats.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 359 (1975), S. 177-182 
    ISSN: 1432-2013
    Keywords: Kidney ; Citrate ; Metabolism ; Concentrating Mechanism ; Medullary Gradient
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The intrarenal distribution of citrate was evaluated in the dog during antidiuresis and osmotic diuresis, by using the specific citrate assay method of Moellering and Gruber. The measurements were made on tissue samples taken from four different regions throughout the kidney: cortex, outer and inner medulla, and papilla. During antidiuresis, a characteristic distribution of citrate was observed with highest levels in the papilla and lowest ones in the outer medulla. A medullary concentration gradient for citrate was found. Mannitol greatly decreased papillary citrate and sodium, but no changes in outer and inner medullary citrate occured. The results could not be explained by the citrate contained either in the trapped urine or blood in the tissue. It is suggested that citrate accumulation in the inner regions of renal medulla may be accounted for by countercurrent mechanisms or regional differences in renal citrate metabolism.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1573-6822
    Keywords: animal ; kidney tubules ; renal pharmacotoxicology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Among the cellular models used in in vitro renal pharmacotoxicology, isolated kidney tubules, used as suspensions mainly of proximal tubules, offer important advantages. They can be prepared in large amounts under nonsterile conditions within 1–2 h; thus, it is possible to employ a great number of experimental conditions simultaneously and to obtain rapidly many experimental results. Kidney tubules can be prepared from the kidney of many animal species and also from the human kidney; given the very limited availability of healthy human renal tissue, it is therefore possible to choose the most appropriate species for the study of a particular problem encountered in man. Kidney tubules can be used for screening and prevention of nephrotoxic effects and to identify their mechanisms as well as to study the renal metabolism of xenobiotics. When compared with cultured renal cell, a major advantage of kidney tubules is that they remain differentiated. The main limitations of the use of kidney tubules in pharmacotoxicology are (1) the necessity to prepare them as soon as the renal tissue sample is obtained; (2) their limited viability, which is restricted to 2–3 h; (3) the inability to expose them chronically to a potential nephrotoxic drug; (4) the inability to study transepithelial transport; and (5) the uncertainty in the extrapolation to man of the results obtained using animal kidney tubules. These advantages and limitations of the use of human and animal kidney tubules in pharmacotoxicology are illustrated mainly by the results of experiments performed with valproate, an antiepileptic and moderately hyperammonemic agent. The fact that kidney tubules, unlike cultured renal cells, retain key metabolic properties is also shown to be of the utmost importance in detecting certain nephrotoxic effects.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...