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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 178 (1988), S. 537-541 
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Frog sciatic nerve ; Axon caliber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frog sciatic nerves show a continuing addition of new myelinated and nonmyelinated fibers with body growth. Along with increases in fiber number there are also marked changes in axon calibers and in the relative thickness of the myelin sheaths. Our data show that frog nerves, as opposed to mammalian nerves, are composed of fibers of different ages, stages of growth and stages of myelination.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 172 (1985), S. 177-182 
    ISSN: 1432-0568
    Keywords: Axon arbor ; Motor fiber ; Nerve fiber branching
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution of fiber branching in the proximal intramuscular motor nerves of the gracilis and gastrocnemius muscles of the rat was studied in whole-mount preparations of teased nerves. Branchings of nerve fibers were clustered at fascicular divisions. Such concurrence of fascicular and fiber branchings determines the dispersion of the single muscle fibers belonging to a motor unit. The distribution of fiber branching reveals the wiring pattern of muscle fibers. These patterns differed for the gracilis and gastrocnemtus muscles in correspondence with their functional organization.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 177 (1987), S. 115-121 
    ISSN: 1432-0568
    Keywords: Myelin sheath thickness ; g Ratio ; Peripheral nerves ; Autonomic nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Computer-assisted measurements of relative myelin sheath thickness (the g ratio) were made in 11 peripheral nerves of the rat. The scatter diagrams showed nerve-specific variations in the distribution of relative myelin sheath thickness. Myelinated fibers of less than 3.5 μm axon diameter had relatively thin myelin sheaths, particularly in the splanchnic, vagus and glossopharyngeal nerves. The oculomoter nerve had two fiber populations clearly set apart in terms of relative myelin sheath thickness. Thickly myelinated fibers were found in facial and hypoglossal nerves. No single functional modality was evident for the thinly myelinated fibers
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 10 (1968), S. 359-362 
    ISSN: 1432-0533
    Keywords: Monocytic cells of CNS ; Radioisotope labelling ; Blood cells entry into the CNS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Eintritt zirkulierender Blutzellen in das Gehirn wurde mittels radioaktiv markierter Zellen aus dem Knochenmark von Spender-auf Empfängertiere untersucht. Die Zellen wurden in vitro oder in vivo mittles H3-Thymidin oder H3-Uridin markiert. Die markierten Zellen vom Charakter der Monocyten oder Makrophagen dringen nach den erhobenen Befunden in normales Hirngewebe ein und sammeln sich in verschiedenartigen Hirnläsionen an. Es ergaben sich Hinweise dafür, daß diese Zellen später in die Milz zurückkehren.
    Notes: Summary The entry of circulating blood cells into the brain was studied by injecting radioactively labeled cells from the bone marrow of donor animals into recipient animals. The cells were labeledin vitro orin vivo, using H3 thymidine or H3 uridine. Labeled cells having features of monocytes or macrophages were shown to enter normal brain tissue and to aggregate at various types of brain lesions. There was indication that these cells later returned to the spleen.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 45 (1979), S. 241-245 
    ISSN: 1432-0533
    Keywords: Myelin formation ; Ganglioglioma ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Formation of myelin sheaths by neoplastic cells was found in a spinal ganglioneuroma. All phases of initial myelination were observed including the formation of a mesaxonal spiral and the fusion of its famellae into a major dense line. A unique aspect of neoplastic myelin formation was the formation of sheaths around bundles of extracellular fibrils rather than axons or cell processes. Formation of myelin sheaths around extracellular material has never been observed before. The findings have implications on the mechanisms controlling initial myelination.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 58 (1982), S. 81-86 
    ISSN: 1432-0533
    Keywords: Dandy-Walker ; Vermis aplasia ; Atresia ; Fourth ventricle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of Dandy-Walker syndrome associated with multiple maldevelopmental lesions of the brain stem and cerebellum is presented. The additional malformations include hypoplasia of both cerebellar hemispheres with multiple foci of cortical dysplasias, rostral dilatation of the fourth ventricle and atresia in its caudal part, hypoplasia of the basis pontis, displacement and dysplasia of several nuclear groups of the medulla oblongata, including subtotal aplasia of the inferior olivar complex, and incomplete decussation of the pyramidal tracts. These lesions implicate a hindrance of neuroblastic proliferation and migration from rhombencephalic cytogenetic zones of the entire alar plate with peristent anterior membranous area.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 64 (1984), S. 75-77 
    ISSN: 1432-0533
    Keywords: Foramen of Monro ; Hydrocephalus ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Unilateral hydrocephalus due to occlusion of one foramen of Monro was found incidentally at necropsy in a 52-year-old man. There was no evidence of a postinflammatory or neoplastic origin of the occlusion. Backward tilting of the diencephalon, asymmetric insertion of the septum pellucidum, lateral tilting of the fornices, and deformation of the hippocampal formation indicated an early developmental origin of the lesion.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 72 (1986), S. 74-81 
    ISSN: 1432-0533
    Keywords: Nerve fiber morphometry ; Computer program ; Myelin sheath thickness ; Tissue preparation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A short guide is given for the planning of nerve fiber morphometry using computer-assisted methods. A new computer program is introduced which allows, among other factors, correction for myelin sheath shrinkage. If myelin shrinkage is not corrected for, there will be false high values for axon caliber and false low values for sheath thickness. The magnitude of the skew produced by this factor is shown on hand from computer editing.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 43 (1978), S. 161-168 
    ISSN: 1432-0533
    Keywords: Porencephaly ; Hydranencephaly polymicrogyria ; Encephalitis ; Toxoplasma cytomegalovirus ; Cortical dysplasias
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty necropsy cases of the association of fetal encephalitis with porencephaly, hydranencephaly or polymicrogyria were reviewed including 5 from the authors' material. The latter include a basket brain, a porencephalic necrosis of recent date and a polymicrogyria in the formative state. The supratentorial lesions are often associated with cerebellar cortical dysplasias. The pathogenetic interdependence of encephalitis and hemispheric defects or malformation is discussed. Examples are given in which the infection appears to be secondary to a pre-existent hemispheric lesion. For others the hemispheric lesions appear to be secondary to encephalitis. In these the encephalitis may produce secondary lesions by a variety of pathogenetic mechanisms.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 55 (1981), S. 75-76 
    ISSN: 1432-0533
    Keywords: Rosenthal fibers ; Glial fibrillary acid protein ; Astrocytoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixteen cases of pilocytic astrocytomas with excessive Rosenthal fiber (RF) formation were examined by the indirect immunoperoxidase method for the localization of glial fibrillary acid protein (GFAP). RF nerve contained GFAP but they were often enclosed in plump and thickened GFAP-positive astrocytic processes. The border between the negative RF and the surrounding positive rim of cytoplasm was always sharp and without gradual transitions. The antigenic difference between RFs and glial filaments imply that glial filaments undergo a profound change in their chemical composition during their transformation into RFs. The possibility that RFs are not degradation products of glial filaments but consist of some chemically unknown substance produced by metabolically activated astrocytes cannot be excluded.
    Type of Medium: Electronic Resource
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