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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 146 (1987), S. 601-602 
    ISSN: 1432-1076
    Keywords: Facial palsy ; Kawasaki disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of facial palsy was reported initially in 1974 by Murayama [8] as one of the neurological manifestations in Kawasaki disease. Thereafter, an additional nine case have been documented in Japan. This facial palsy, in the revised “Diagnostic Guideline of Kawasaki Disease” released in 1984, has been added recently as one of the neurological signs and symptoms of Kawasaki disease. This is a report on two cases of Kawasaki disease showing facial palsy with indurative oedema during their clinical course, and also a clinical review of the ten previously reported cases of facial palsy complicating Kawasaki disease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 149 (1989), S. 18-19 
    ISSN: 1432-1076
    Keywords: Plasma renin activity ; Plasma aldosterone concentration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Infants and toddlers often start crying at venopuncture and the stress of crying has been known to increase the levels of plasma renin activity (PRA) and plasma aldosterone concentration (PAC), but no precise information is available. We measured the levels of PRA and PAc in blood samples taken from 30 infants and toddlers within 1 min after the onset of crying, as induced by venopuncture, and 3 and 5 min after continuation of crying (PRA1.0, PRA3.0, PRA5.0, and PAC1.0, PAC3.0, PAC5.0). The age of these subjects ranged from 1 to 30 months (median 16 months). PRA1.0, PRA3.0 and PRA5.0 were 4.0±1.8 ng/ml per hour, 5.5±2.7 ng/ml per hour, and 7.8±4.2 ng/ml per hour, respectively. PAC1.0, PAC3.0 and PAC5.0 were 210±110 pg/ml, 231±118 pg/ml and 269±145 pg/ml, respectively. Both PRA and PAC increased with elapsing time. The increase in PRA was marked after a short episode of crying, but that in PAC was of a mild degree.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1076
    Keywords: Key words Isolated 3-methylcrotonyl-coenzyme A car boxylase ; Newborn mass screening ; Gas chromatog raphy-mass spectrometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe an asymptomatic male infant with isolated 3-methylcrotonyl-coenzyme A carboxylase deficiency who came to medical attention by newborn mass screening due to elevated blood leucine. The diagnosis was made by abnormal urinary organic acids at 20 days of age and was confirmed by assay of the carboxylase activities in cultured skin fibroblasts. Conclusion More attention should be paid to slight elevations of leucine levels in newborn mass screening. Urinary organic acid analysis should be performed in conspicuous cases.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1076
    Keywords: Kawasaki disease ; Thrombocytopenia ; Aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thrombocytopenia was observed in 10 (2.0%) of 486 children with Kawasaki disease. In nine of the ten, the minimal paltelet count of 94000±38000 (SD)/mm3 was seen on day 6.8±2.2 (SD) of illness and the platelet counts were elevated to the normal level in 1–2 weeks. Thrombocytopenia in the nine appeared to be caused via coagulation-mediated platelet consumption, while the remaining child was diagnosed as having idiopathic thrombocytopenic purpura. One of the two who had severe coagulation-mediated thrombocytopenia of less than 50000/mm3 developed coronary aneurysms persisting over 1 year.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1920
    Keywords: Key words Shunt ; portosystemic ; Globus pallidus ; Manganese ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report two toddlers with portosystemic shunts who had symmetrical high-signal globus pallidus lesions on T1- but not T2-weighted MRI, and measurement of whole blood manganese at 2 years of age. These cases suggest that portosystemic shunts can cause elevation of blood manganese and result in manganese accumulation in the globus pallidus, causing high signal on T1-weighted images even in asymptomatic toddlers.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1971
    Keywords: Key words: Kawasaki disease — Coronary aneurysm — Myocardial infarction — Coronary angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. From January 1973 through December 1992, a total of 302 patients (183 males, 119 females) with Kawasaki disease (KD) underwent coronary angiography. The age at onset of KD ranged from 2 months to 12.3 years (median 1.4 years). The age at the first angiographic evaluation ranged from 6 months to 17 years (median 3.5 years). Most of the patients (85%) had suffered from KD before 1985 and thus were treated without benefit of γ-globulin. Follow-up varied from 6 months to 25.8 years (median 13.6 years). Coronary abnormalities were confirmed in 71 (23.5%) of 302 patients; the left coronary artery (LCA) alone was involved in 36 cases, the right coronary artery (RCA) alone in 10 cases, and both arteries in 25 cases. Serial angiographic evaluation of the 42 cases revealed different attitudes in the progress of coronary abnormalities. All large aneurysms showed a tendency to regress, although some progressed to stenotic lesions. Moderate aneurysms stayed unchanged, regressed, or progressed to stenosis or obstruction. Small aneurysm never became stenotic and frequently regressed to normal internal diameter. Aneurysms of the RCA tended to regress relatively early during the follow-up period, whereas those of the LCA gradually progressed to stenotic lesions. In 7 of 35 patients with RCA lesions, aneurysms progressed to complete obstruction and subsequent recanalization within 0.5 to 7.7 years (median 3.6 years) after the onset of KD. Most of the patients with coronary artery sequelae after KD remain asymptomatic. Serial angiographic observation is indicated for those patients who develop large coronary aneurysms during the acute phase of KD. The standard 12-lead electrocardiogram, chest roentgenogram, and exercise stress test are less sensitive for detecting and evaluating patients with coronary sequelae. For the screening of myocardial ischemia after KD, stress thallium 201 scintigraphy with dipyridamole infusion is recommended.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric cardiology 17 (1996), S. 382-386 
    ISSN: 1432-1971
    Keywords: Key words: Ventricular septal defect — Congestive heart failure — Right ventricular volume overload
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The hemodynamic features of 44 patients requiring surgical closure of a ventricular septal defect (VSD) during early infancy were evaluated. The VSD was closed within the first 6 months of life in 29 patients (group A) and during the second 6 months in 15 patients (group B). The left-to-right (L–R) shunts were significantly greater in group A than in group B, although in all patients they were more than 50%. In contrast, the left ventricular end-diastolic volume was significantly greater in group B than in group A, whereas the right ventricular end-diastolic volume was greater in group A; the difference was not statistically significant. The step-up in blood oxygen saturation in the lower right atrium, which was significantly more in group A, indicated the L–R shunt across the patent foramen ovale (PFO). The L–R shunt across the VSD during diastole was also detected in all patients angiographically. With early infantile VSD, the larger the L–R shunt the greater was the likelihood of early surgery. Right ventricular volume overload caused by the L–R shunt across a PFO as well as through the VSD during diastole is a useful indicator of a large shunt in infants with VSD.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric cardiology 15 (1994), S. 127-131 
    ISSN: 1432-1971
    Keywords: Echocardiography ; Infective endocarditis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The medical records of the 29 patients under 18 years of age with infective endocarditis (IE) seen over a 20-year period by our department were reviewed to provide an overview of the spectrum of IE during infancy and childhood. None of the 29 patients had had previous cardiovascular surgery. The mean age at onset of IE was 7 years 2 months; 3 patients (10%) were under 2 years of age at onset. One patient during the early years died following 4 months of treatment with various antibiotics. Three patients underwent urgent surgery, and 17 patients with healed IE had elective surgery. All of the 20 patients who were operated on survived. The remaining 8 were followed with medical treatment alone. Positive blood cultures were obtained from 24 (83%) patients, and streptococci were still commonly found (38%). Ventricular septal defect (VSD) accounted for 66% of underlying heart diseases and rheumatic heart diseases for 14%. Vegetations were detected in 12 (67%) of 18 patients observed by echocardiography. Among these 12 patients, 1 with VSD underwent urgent tricuspid valve replacement and VSD closure because of worsening congestive heart failure due to progressive tricuspid regurgitation. Echocardiography identifies patients at high risk with IE, though the presence of a vegetation on echocardiography does not necessarily of itself dictate surgical intervention.
    Type of Medium: Electronic Resource
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