ISSN:
0749-1581
Keywords:
LH-RH
;
1H NMR
;
13C NMR
;
Conformational parameters
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The structure of LH-RH in DMSO solution was studied using 2D NMR experiments at 600 MHz. The 13C NMR spectrum was completely assigned by the combined use of 1H-detected heteronuclear multiple-quantum coherence and 1H-detected multiple-bond heteronuclear multiple-quantum coherence. Measured 1J(CH) values were used to obtain the possible sets of Φ and Ψ dihedral angles. These features, together with some relevant dipolar interactions observed in the ROESY spectrum, were interpreted to provide evidence of some degree of intramolecular structuring.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260320908
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