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  • 1
    Electronic Resource
    Electronic Resource
    Astringency Principles, Changes in Phenolic Content in Persimmons during Ripening and Processing (1964)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 12 (1964), S. 511-520 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60136a008
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  • 2
    Electronic Resource
    Electronic Resource
    Preparation and spectral properties of lipophilic fluorescein derivatives: application to plasma low-density lipoprotein (1981)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 103 (1981), S. 7396-7398 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00414a087
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  • 3
    Electronic Resource
    Electronic Resource
    Tracking adult North Atlantic bluefin tuna (Thunnus thynnus) in the northwestern Atlantic using ultrasonic telemetry (2000)
    Springer
    Marine biology 137 (2000), S. 347-358 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ultrasonic, depth-sensitive transmitters were used to track the horizontal and vertical movements, for up to 48 h, of 11 adult (136 to 340 kg estimated body mass) North Atlantic bluefin tuna (Thunnus thynnus Linnaeus). Fish were tracked in October 1995, September and October 1996, and August and September 1997 in the Gulf of Maine, northwestern Atlantic. The objective was to document the behavior of these fish and their schools in order to provide the spatial, temporal, and environmental information required for direct (i.e. fishery-independent) assessment of adult bluefin tuna abundance using aerial surveys. Transmitters were attached to free-swimming fish using a harpoon attachment technique, and all fish remained within the Gulf of Maine while being followed. Most of the bluefin tuna tagged on Stellwagen Bank or in Cape Cod Bay (and followed for at least 30 h) held a predominately easterly course with net horizontal displacements of up to 76 km d−1. Mean (±SD) swimming depth for all fish was 14 ± 4.7 m and maximum depth for individuals ranged from 22 to 215 m. All but one fish made their deepest excursions, often single descents, at dawn and dusk. In general, adult bluefin tuna spent 〈8% of their time at the surface (0 to 1 m), 〈19% in the top 4 m, but 〉90% in the uppermost 30 m. Mean (±SD) speed over ground was 5.9 km h−1, but for brief periods surpassed 20 to 31 km h−1. Sea surface temperatures during tracking were 11.5 to 22.0 °C, and minimum temperatures encountered by the fish ranged from 6.0 to 9.0 °C. Tagged bluefin tuna and their schools frequented ocean fronts marked by mixed vertebrate feeding assemblages, which included sea birds, baleen whales, basking sharks, and other bluefin schools.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002270000302
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  • 4
    Electronic Resource
    Electronic Resource
    Accumulation of Amino-acids in Plant Cell Tissue Cultures (1963)
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 1302-1303 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1. AMINO-ACII )S AND Al JJOHEXOSES 11 * CULTURES GR OWN (a) WITH AND (6) WITHC 〉UT FREE Ace !ESS OF AIR Culture Amino -acids Suga irs (a) (&) (a) 〈&) Bean 8-5 40-2 67 60 Sycamore 4-2 25-1 109 103 Rose 19-4 47-0 7-3 5-8 Haplopapus 7-2 60 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1991302a0
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  • 5
    Electronic Resource
    Electronic Resource
    The LDL Receptor Locus in Familial Hypercholesterolemia: Mutational Analysis of a Membrane Protein (1990)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 24 (1990), S. 133-170 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.24.120190.001025
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  • 6
    Electronic Resource
    Electronic Resource
    The LDL Receptor Locus and the Genetics of Familial Hypercholesterolemia (1979)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 13 (1979), S. 259-289 
    Details
    ISSN: 0066-4197
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ge.13.120179.001355
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of high-energy neutron flux on fiber optics in an active diagnostic on TFTR (abstract)a) : Proceedings of the tenth topical conference on high temperature plasma diagnostics (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 919-919 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A bundle of 1-mm-diam fused silica optical fibers on an existing TFTR diagnostic has been exposed to 11 high-power DT discharges. Each shot subjected the fibers to a peak fast (14.7 MeV) neutron flux of ≈2×1012 n/cm2/s and a γ-dose rate of 500 rad(Si)/s for 0.75–1.0 s. The total fast-neutron fluence for these shots was ≈5×1012 n/cm2. A 15-m-long section of the bundle ran along the tokamak's toroidal field coils and the remaining 15 m ran radially away from the reactor. Fiber luminescence at 660 nm was ≈1010 photons/s/sr/cm2/A(ring) for the above flux (≈5%–10% of the bremsstrahlung emission), and varied linearly with DT neutron rate. Luminescence at 530 nm was 50% stronger, consistent with a Cerenkov radiation spectrum. Sensitivity to 3.5 MeV DD neutrons was ≈1/3 to 1/2 of that for DT neutrons. Fiber transmission decreased with the time integral of the neutron source rate and was reduced by 4% for the above flux. The fiber recovered rapidly: within 10 s, the transmission loss was only 2.5%. Shortly thereafter, the rate of recovery slowed to ≈0.05% per minute, but was sufficient to restore 75% of the transmission loss within two to four discharges. Recovery continued at ≈0.1% per hour and slowed overnight to ≈0.1% per day. Within the relative error of 〈0.2%, full transmission was recovered after five days. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146205
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of high-energy neutron flux on fiber optics in an active diagnostic on TFTRa) (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 1252-1255 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A bundle of 1-mm-diam fused silica optical fibers on an existing TFTR diagnostic has been exposed to 11 high-power DT discharges. Each shot subjected the fibers to a peak fast (14.7 MeV) neutron flux of ≈2×1012 n/cm2/s and a γ-dose rate of 500 rad(Si)/s for 0.75–1.0 s. The total fast-neutron fluence for these shots was ≈5×1012 n/cm2. A 15-m-long section of the bundle ran along the tokamak's toroidal field coils and the remaining 15 m ran radially away from the reactor. Fiber luminescence at 660 nm was ≈1010 photons/s/sr/cm2/A(ring) for the above flux (≈5%–10% of the bremsstrahlung emission), and varied linearly with DT neutron rate. Luminescence at 530 nm was 50% stronger, consistent with a Cerenkov radiation spectrum. Sensitivity to 3.5 MeV DD neutrons was ≈1/3 to 1/2 of that for DT neutrons. Fiber transmission decreased with the time integral of the neutron source rate and was reduced by 4% for the above flux. The fiber recovered rapidly: within 10 s, the transmission loss was only 2.5%. Shortly thereafter, the rate of recovery slowed to ≈0.05% per minute, but was sufficient to restore 75% of the transmission loss within two to four discharges. Recovery continued at ≈0.1% per hour and slowed overnight to ≈0.1% per day. Within the relative error of 〈0.2%, full transmission was recovered after five days. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146016
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  • 9
    Electronic Resource
    Electronic Resource
    Dyspepsia tolerability from the patients' perspective: a comparison of celecoxib with diclofenac (2002)
    Oxford UK : Blackwell Science Ltd.
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To compare celecoxib (800 mg/day, n=1997) with diclofenac (150 mg/day, n=1996) on dyspepsia-related tolerability.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:In one of the two protocols comprising the Celecoxib Long-Term Arthritis Safety Study, a randomized double-blind trial, patients completed the Severity of Dyspepsia Assessment Questionnaire at baseline and at weeks 4, 13, 26 and 52 for the following three scales: Pain Intensity, Non-Pain Symptoms and Satisfaction with Dyspepsia-Related Health.〈section xml:id="abs1-3"〉〈title type="main"〉Results:For the Pain Intensity scale, patients given diclofenac had significantly higher (worsening dyspepsia) mean changes, defined as follow-up minus baseline, than patients given celecoxib (P 〈 0.001, at all assessments). The mean changes in the Pain Intensity scale (scale, 2–47; higher score is higher pain intensity) were 0.99 (95% confidence interval (CI): 0.50, 1.48) for celecoxib and 2.76 (95% CI: 2.28, 3.25) for diclofenac at 4 weeks. Satisfaction was superior with celecoxib at all assessments (P 〈 0.001). At 4 weeks, the mean changes in the Satisfaction scale (scale, 7–35; higher score is higher satisfaction) were 0.02 (95% CI: − 0.26, 0.29) for celecoxib and − 0.72 (95% CI: − 1.00, − 0.45) for diclofenac. Diclofenac patients had significantly higher Non-Pain Symptoms at 4 weeks (P=0.005).〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions:Celecoxib, at two to four times the recommended dose, demonstrated a superior dyspepsia-related tolerability and satisfaction compared with standard dosages of diclofenac.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2002.01219.x
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  • 10
    Electronic Resource
    Electronic Resource
    A comparison of the upper gastrointestinal mucosal effects of valdecoxib, naproxen and placebo in healthy elderly subjects (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 18 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : In long-term outcomes studies, cyclooxygenase COX-2 specific inhibitors spare COX-1 at supratherapeutic doses and therefore demonstrate improved gastrointestinal safety over nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs). However, in clinical practice, anti-inflammatory drugs are often used for short-term treatment of pain.Aim : To compare the short-term upper gastrointestinal mucosal effects of naproxen with the new COX-2 specific inhibitor, valdecoxib, or placebo, in elderly subjects.Methods : In this multicentre, double-blind, randomized, study, elderly subjects (65–76 years old), with a normal baseline esophagogastroduodenoscopy (EGD), received oral valdecoxib (a supratherapeutic 40 mg b.d. dosage, n = 62), naproxen (500 mg b.d., n = 62), or placebo (n = 62) for 6.5 days. Upper gastrointestinal mucosal injury was evaluated post-treatment by EGD (day 7).Results : Subjects receiving naproxen (11/60, 18%) had significantly more gastroduodenal ulcers post-treatment than those receiving placebo (2/61, 3%; P 〈 0.01) or valdecoxib (0/60, 0%; P 〈 0.001). A similar significant finding was observed for gastric ulcer rates. All treatments had similar adverse event rates and clinical laboratory findings.Conclusions : Valdecoxib, even at supratherapeutic doses, was associated with an ulcer rate significantly lower than naproxen but similar to placebo in healthy elderly subjects, despite the short duration of therapy (6.5 days). Naproxen and valdecoxib were as well tolerated as placebo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01650.x
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