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  • 1
    ISSN: 1432-0460
    Keywords: Gastroesophageal reflux ; Gastroesophageal reflux model ; Deglutition ; Deglutition disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this paper, the isolated influence of physical factors on the development of gastroesophageal reflux in man is analyzed by means of a mechanical model. We evaluate the influence of gravity, intraabdominal presure, intrathoraci pressure, transmission of intraabdominal pressure to the high pressure zone, filling volume of the stomach, and the existence of a high pressure zone on the appearance of gastroensophageal reflux. PH-metry is used to record the episodes of reflux in the model. We wish to demonstrate the importance of gravity and intraabdominal pressure in the production of reflux. Intrathoracic pressure acts as an antireflux mechanism only when associated with a zone of high pressure. The intraabdominal pressure may be transmitted to the high pressure zone as a purely mechanical effect and the greater gastric filling volume may, when associated with the intraabdominal pressure, facilitate reflux without physical changes in the high pressure zone (the equivalent of a reduction in the length of the lower esophageal sphincter in man). We conclude that this model may help to explain the influence of the physical factors mentioned above on the development of gastroesophageal reflux in man.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1436-2813
    Keywords: carcinoma of the cardia ; esophagogastrectomy ; isoperistaltic transverse colon interposition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract With the object of designing a feasible and more radical surgical intervention for the treatment of carcinoma of the gastric cardia and improving the long term survival of these patients, a procedure was described which entails total esophagogastrectomy and resection of the distal pancreas, spleen and regional lymphnodes. The esophagus was mobilizedvia the diaphragmatic hiatus without thoracotomy. Intestinal continuity, installed isoperistaltically was restituted in the same operation using a segment of transverse and descending colon transferred to the left lateral cervial aspect by way of the posterior mediastinum. The procedure was used in four patients and mortality and serious complications were nil.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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