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  • 1
    Electronic Resource
    Electronic Resource
    Sjoegren's syndrome: MR imaging of the parotid gland (1996)
    Springer
    European radiology 6 (1996), S. 46-51 
    Details
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To date, myoepithelial sialoadenitis (Sjoegren's syndrome) has been diagnosed with sialography and other techniques. First results of MR imaging offer new possibilities in the diagnostic imaging of this Thirty-six pat nts with immunohistologically and serologically confirmed Sjoegren s syndrome and 25 patients suffering from other diseases, included as a control group, were examined by MR in transverse and coronal orientation T-2 weighted sequneces (TR/TE- 1600/25/90) and T- weighted sequences (TR/TE 500/25 msplainand after (Gd-DTPA administration were obtained. In all patients the parotid gland showed characteristics internal paterns and abnormalities in gland size. There was a 21 nonhomogeneous internal pattern wit a characteristicsc speckled, honeycomb-like appearance visible especially on T2-weighted sequences. Enhancement with Gd-DTPA yielded no additional information. A staging system with four stages of Sjoegren's syndrome (no characteristics changes to a nodular and swollen gland) was developed. Magnetic resonance has become an important new tool in assessing parotid gland changes in patients suffering from Sjoegren's syndrome, and could well replace the more invasive and unpleasant diagnostic methods in the near future.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00619951
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  • 2
    Electronic Resource
    Electronic Resource
    Closure of Recurrent Frontal Skull Base Defects with Vascularized Flaps – A Technical Case Report (2000)
    Springer
    Acta neurochirurgica 142 (2000), S. 1353-1358 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: CSF rhinorrhea; skull base defects; vascularized flaps.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Techniques for vascularized reconstruction of the anterior cranial fossa floor defects causing recurrent cerebrospinal fluid fistula are discussed in this report. The closure employs the use of local random- or axial-pattern vascularized flaps in simple cases. In complicated cases (for instance, status after repeated exploration) the tissue of the cranial base is severely compromised and shows low potential for healing. Non-vascularized grafts only add avital scars to the already present ones leading to recurrent fistulas. Free vascularized flaps show more mechanical strength and less scar contraction, resistance to infections and survive better in a compromised surrounding, thus leading to long term sealing in such cases. The technical issues of vascularized closure of defects of the frontal skull base are discussed in this report.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010070004
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  • 3
    Electronic Resource
    Electronic Resource
    Volatiles of Apples During Storage and Ripening (1965)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 30 (1965), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1965.tb01778.x
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  • 4
    Electronic Resource
    Electronic Resource
    SETTING TIME AND SETTING TEMPERATURE OF PECTIN JELLIES (1960)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 25 (1960), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1960.tb00008.x
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  • 5
    Electronic Resource
    Electronic Resource
    Involvement of inferior turbinate mucosa in chronic sinusitis – localization of T-cell subset (2000)
    Copenhagen : Munksgaard International Publishers
    Allergy 55 (2000), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: In chronic sinusitis (CS), different subsets of leukocytes are involved in development of persistent inflammation of the nasal mucosa. The localization and differentiation of these infiltrating lymphocytes may help us to understand the inflammatory interactions in the epithelium, lamina propria, and seromucous glands of the nasal mucosa in CS. Methods: We examined frozen sections of inferior turbinates from 14 patients with nonallergic CS and 10 normal nonallergic controls. We used the avidin-biotin-peroxidase (ABC) technique with monoclonal antibodies against CD3 (total T cells), CD4 (T-helper/inducer cells), CD8 (T-suppressor/cytotoxic cells), CD22 (B cells), CD56 (natural killer cells), elastase (neutrophil granulocytes), eosinophil cationic protein (eosinophil granulocytes), and CD68 (macrophages). Results: We found significant increases (P〈0.05) of CD3, CD4, and CD8 T cells and B cells in the nasal mucosa of patients with CS. The number of CD68 cells and eosinophils showed no significant rise. Conclusions: The different types of leukocytes play a key role in the defense of the respiratory tract. The analysis of the distribution of cells in the epithelium, mucosa, and glands of the inferior turbinate confirmed that nonallergic CS is, in fact, chronic, bacterial rhinosinusitis involving the inferior turbinates, and that the pathomechanism is therefore different from that of nasal polyposis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2000.00411.x
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  • 6
    Electronic Resource
    Electronic Resource
    3D MR imaging with Gd-DTPA in head and neck lesions (1991)
    Springer
    European radiology 1 (1991), S. 151-157 
    Details
    ISSN: 1432-1084
    Keywords: 3D-MRI ; ray-tracing ; head nad neck ; 3D-reconstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three-dimensional MR imaging technique is not a new concept, however, there is very little experience concerning clinical trials. Especially in head and neck lesions, the accuracu of this new imaging method has not yet been tested. A pilot study was performed to evaluate the diagnostic value of demonstrating the head and neck lesions and topographical structures implemented in a three-dimensional reconstruction of the entire head. The 3D reconstruction mode is based on the ray-tracting model. The application of the contrast medium Gd-DTPA proved to be helpful. Three-dimensional reconstruction revealed clear topographic details of the lesions, including the spread of infiltration and destruction of soft tissue. Additionally, the simultaneous view of multiple slices in different orientations is an ideal method for evalauting the spread of the lesion and to visualize the relation between lesion and surrounding tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00451299
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  • 7
    Electronic Resource
    Electronic Resource
    MRI with Gd-DTPA in tumours of larynx and hypopharynx (1991)
    Springer
    European radiology 1 (1991), S. 58-64 
    Details
    ISSN: 1432-1084
    Keywords: MRI ; Larynx ; Hypopharyngeal tumours ; Contrast media
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twenty-eight patients with tumours of the larynx, divided into supraglottic, glottic, and subglottic lesions, and of the hypopharynx were examined by different MRI techniques using the paramagnetic contrast medium Gd-DTPA. The results of preoperative MRI were compared with clinical laryngoscopy and the pathological tumour classification. The examinations were carried out using plain T1-wand T2-weighted and Gd-DTPA enhanced T1-weighted sequences. Most studies included three slice orientations for optimal assessment of different tumour locations. The most accurate diagnostic information was given by Gd-DTPA-enhanced sequences. The combination of plain images, contrast-enhanced images and subtraction enabled precise assessment of deep infiltration. T2-weighted and proton density sequences conveyed more information about cartilage invasion and liquid-filled structures, but gave more artefacts than T1-weighted images. Laryngoscopy had advantages in T1-classified tumors, as the extent of the tumor could be seen, and offered histological information via biopsy. Diagnostic findings of MRI correlated in 85.7% with the pathologist's report, and laryngoscopy provided exact classification in only 64.3% of patients. Gd-DTPA-enhanced MRI is an important adjunct to non-contrast MR studies, and forms an ideal diagnostic supplement to laryngoscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00540106
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  • 8
    Electronic Resource
    Electronic Resource
    Hochmalignes T-Zell-Non-Hodgkin-Lymphom (nasal type) des harten Gaumens (2000)
    Springer
    HNO 48 (2000), S. 318-322 
    Details
    ISSN: 1433-0458
    Keywords: Schlüsselwörter ; Nasales T-Zell-Lymphom ; Letales Mittelliniengranulom ; Wegener-Granulomatose ; Keywords ; Nasal T-cell lymphoma ; Lethal midline granuloma ; Wegener’s granulomatosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The monomorphic clinical aspect of destructive mid-face lesions is characterised by inflammation, induration and granulomatous transformation. This feature can be caused by various infections, toxical noxa, Wegener’s Granulomatosis and different neoplasms. The case of a 19 year old patient with EBV associated nasal type T-cell lymphoma located at the hard palate is presented. The diagnostic approach and difficulties in diagnosing this entity assessing by using multiple biopsies, serological and molecularbiological detection of EBV association and immunohistochemistry for atypic T-cells are elucidated. In the presented case the treatment with chemotherapy and irradiation following a well-defined therapy concept leaded to a three year recurrence-free survival so far. The comparison of the key-histological findings and the major differential diagnoses is mandatory to establish the final diagnosis of lymphoma. This is the basement for treating this disease with combined chemotherapy and irradiation for optimizing survival.
    Notes: Zusammenfassung Das klinisch weitgehend monomorphe Bild eines destruktiven Mittelgesichtprozesses ist gekennzeichnet durch Veränderungen in Folge von Entzündung, Infiltration und granulomatösen Umbauvorgängen. Am Fall eines 19jährigen Patienten mit einem seltenen EBV-assoziierten hochmalignen Non-Hodgkin-T-Zell-Lymphom am harten Gaumen werden die Schwierigkeiten bis zur endgültigen Diagnosefindung dargestellt. Anhand der Literatur werden die unterschiedlichen Begriffsdefinitionen von destruierenden Mittelgesichtsveränderungen verschiedener Autoren aufgezeigt. Nur über eine differenzierte klinische, mikrobiologische, serologische und histologische Diagnostik ist eine Abgrenzung gegenüber verschiedenen Infektionen, toxischen Noxen, der Wegener-Granulomatose und diversen Neoplasien zu erreichen. Hierdurch wird die überlebenswichtige Kombinationstherapie aus Chemotherapie und Bestrahlung möglich.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001060050573
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  • 9
    Electronic Resource
    Electronic Resource
    Scanning electron microscopic studies of the nasal blood vessels (1988)
    Springer
    European archives of oto-rhino-laryngology and head & neck 244 (1988), S. 363-366 
    Details
    ISSN: 1434-4726
    Keywords: Scanning electron microscopy ; Nasal mucosa ; Blood vessels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Current histological and transmission electron microscopic techniques are insufficient for studying all different aspects of vascular morphology. As a result, we have used scanning electron microscopy (SEM) to examine nasal blood vessels. In our present studies the nasal septa of 15 rabbits were fixed by vascular perfusion, dried by the critical point method and coated with gold for SEM studies. Lower magnifications of specimens using this method show the tissue arrangement in the nasal septum. In higher magnifications the different vessels can be distinguished by their morphological features. The course of the vascular structures can be obverved as well as the junctions between the different vessels. Our results indicate that different morphological techniques must be combined to understand the endonasal vasculature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00497466
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  • 10
    Electronic Resource
    Electronic Resource
    Morphological variability of smooth muscle cells in human nasal swell bodies (1996)
    Springer
    European archives of oto-rhino-laryngology and head & neck 253 (1996), S. 147-151 
    Details
    ISSN: 1434-4726
    Keywords: Nasal swell bodies ; Morphology ; Smooth muscle cell ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The complex functional behavior of nasal swell bodies is still not completely understood. In the present study the histology of the vessels involved in the swelling mechanism is examined and the ultrastructural appearances described of the different types of smooth muscle cells located in the vascular wall of swell bodies in the human inferior turbinate. Even though the majority of smooth muscle cells of the nasal swell bodies showed a normal, elongated appearance comparable to other smooth muscle cells elsewhere in the body, a variety of cells with atypical shapes could be detected that have not been described previously in vessels of the nasal mucosa. The diameters of the smooth muscle cells in general were strikingly variable. The individual smooth muscle cells were surrounded by a basal lamina that was occasionally disrupted or doubled. Myoblasts were separated by a connective tissue space containing collagen fibrils, mature elastin fibers and bundles of microfibrils. The latter two types of fibers and fibrils occurred mainly in the outer parts of the muscular coat. The endowment of cytoplasmic components was similar in all smooth muscle cells of the vascular wall in the swell bodies. These findings indicate that the specific feature of smooth musculature presumably resides in the unusual morphological variability of the single cells present, as well as in the striking heterogeneity of the arrangement of bundles of these cells in the vascular wall.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00615112
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