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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 36 (1980), S. 458-459 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The erythropoietic effects in exhypoxic polycythemic mice of two endoperoxide analogs were assessed and compared with PGE2. The 9a, 11a epoxymethano analog (U-44069) was found to be a much more potent erythropoietic stimulus than the 11a,9a analog (U-46619) or PGE2.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The biological profile of three of these inhibitors was assessed in rats and dogs by the antagonism of the presser response to angiotensin I. High converting-enzyme inhibitory activities (at doses as low as 2.3 g per kg) were demonstrated after intravenous (i.v.) administration. Given orally (p.o.) ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 221 (1984), S. 167-170 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Direct comparison of drug interaction with intraocular relative to extraocular β-adrenergic receptors was used to test the hypothesis that the receptors in ocular tissues are of the β2-subtype. Potencies for the displacement of3H-dihydroalprenolol radioligand binding to membranes obtained from rabbit-iris ciliary bodies by β-adrenoceptor agonists was in the order: isoproterenol ≧ epinephrine 〉 salbutamol 〉 terbutaline 〉 tazolol 〉 norepinephrine. Similar radioligand displacement by β-adrenoceptor antagonists was in the order of potency: alprenolol ≧ bupranolol = oxprenolol = timolol = propranolol 〉 ICI 118,551 = IPS 339 ≫ betaxolol 〉 metoprolol. Finally, for the above β-adrenoceptor antagonists, a highly significant correlation was obtained for displacement of radioligand to ocular tissues (pKi values) relative to antagonism (pA2 values) of isoproterenol-induced guinea-pig tracheal relaxation but not guinea-pig atrial chronotropic effects. Consequently, the above three observations reinforce the notion that rabbit-iris ciliary bodies contain β-adrenergic receptors predominantly of the β2-subtype.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 223 (1985), S. 168-168 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Applied psychophysiology and biofeedback 17 (1992), S. 41-57 
    ISSN: 1573-3270
    Keywords: semantic ERP ; event related potential ; learning disability ; ADHD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cortical event-related potentials (ERP) were recorded over FZ, CZ, and PZ scalp sites in 15 learning-disabled (LD), 14 gifted (G), and 13 normal control (N) children of ages 8–12. The common stimulus consisted of nouns presented 80 percent of the time; the target stimulus of animal names presented 20 per cent of the time. ERPs were averaged over subjects from 180 msec pre-stimulus to 900 msec post-stimulus. Principal components analysis was used to determine if there were amplitude differences at different post-stimulus latencies as a function of condition. Differences in ERP's between groups (LD, gifted, and controls), scalp locations, and common versus target stimuli were analyzed by ANOVAs. P 3 , Late, P 2 , and N 1 components represented by four factors were identified. Significant differences between G and LD and the N and LD groups were found target stimulus at all central locations for the P 3 component. Differences were found centrally between G and LD, G and N, and N and LD groups for the P 2 component centrally. Other differences were found for the N 1 and late components. These differences could be interpreted as a deficit in either attentional mechanisms or information processing for the LD group.
    Type of Medium: Electronic Resource
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