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  • 1
    Electronic Resource
    Electronic Resource
    Effect of phospholipids on purified lipoamidase (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 459-461 
    Details
    ISSN: 1420-9071
    Keywords: Porcine brain lipoamidase ; activation and inhibition by phospholipids ; phosphatidylethanolamine ; phosphatidylserine ; phospholipase A2 ; microsome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Phospholipids were added to purified lipoamidase from porcine brain microsomal membranes, and changes in lipoamidase activity were examined. Approximately twofold activation of lipoamidase activity occurred upon the addition of phosphatidylethanolamine. On the other hand, phosphosphatidylserine, cardiolipin, and phosphatidic acid reduced the enzyme activity by approximately 80%. This pattern of the activation of lipoamidase by phosphatidylethanolamine and its inhibition by phosphatidylserine is similar to the pattern for adenylate cyclase, and contrasts with the pattern for ATPase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954229
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  • 2
    Electronic Resource
    Electronic Resource
    Senile dementia of Alzheimer type characterized by laminar neuronal loss exclusively in the hippocampus, parahippocampus and medial occipitotemporal cortex (1990)
    Springer
    Acta neuropathologica 80 (1990), S. 575-580 
    Details
    ISSN: 1432-0533
    Keywords: Senile dementia of Alzheimer's type ; Alzheimer's disease ; Pick's disease ; Laminar neuronal loss ; Limbic system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Seven cases of senile dementia of Alzheimer type (SDAT) with unusual clinico-pathological findings are reported. The patients showed neuronal loss in laminar pattern, with gliosis exclusively confined to the CA1 of the hippocampus, the area of the hippocampal gyrus (entorhinal cortex) and medial occipitotemporal cortex. This change was more pronounced in the oral region. The subcortical white matter showed more pronounced fibrillary gliosis than loss of myelin. Both Alzheimer's neurofibrillary tangles and senile plaques were less marked than those usually seen in SDAT. The mental disturbance started after the age of 65 in all patients. The main clinical feature was marked character change in addition to disturbance of cognitive function. Cranial computed tomography showed marked dilatation of the oral portion of the inferior horn of the lateral ventricle in the early stage. It was apparent that although the cases in this group could be incorporated within in the spectrum of SDAT, they could also be considered to represent a variant of SDAT. This group could contribute to an understanding of the clinico-pathological spectrum of SDAT as well as indicating ways of managing such patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307623
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  • 3
    Electronic Resource
    Electronic Resource
    Peliosis of the spleen: splenic rupture with intraperitoneal hemorrhage (1998)
    Springer
    Abdominal imaging 23 (1998), S. 201-202 
    Details
    ISSN: 1432-0509
    Keywords: Key words: CT—Spleen—Peliosis—Rupture.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Peliosis is a rare disease that is characterized by multiple blood-filled cystic spaces. We report the computed tomographic findings of splenic rupture secondary to splenic peliosis in a patient receiving anabolic steroids for aplastic anemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900323
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  • 4
    Electronic Resource
    Electronic Resource
    Paraneoplastic cortical cerebellar degeneration (1988)
    Springer
    Acta neuropathologica 77 (1988), S. 206-212 
    Details
    ISSN: 1432-0533
    Keywords: Paraneoplastic cortical cerebellar degeneration ; Cerebellar vermis ; Patchy distribution ; Purkinje cell dendrite ; Alcoholic cortical cerebellar degeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case is described of paraneoplastic cortical cerebellar degeneration in a patient with a small cell carcinoma of the lung. Following therapy, clinical improvement of cerebellar ataxia had been observed. The most severe degeneration was found in the superior aspects of the vermis and in the anterior and simple lobes as well as in the inferior aspects of the hemisphere. In addition to this distribution of degenerative lesions, uneven loss of Purkinje cells was apparent. Such distribution patterns in this case were apparently compatible with those of alcoholic cortical cerebellar degeneration (ACD), although the lesions were less severe than in ACD. Furthermore, dendritic changes in the Purkinje cells including loss of the spiny branchlets, focal swelling of the dendrites, and disappearance of secondary and tertiary branches were remarkable. It is noteworthy that these cells showed various stages of degeneration before cell loss occurred. These data suggest that the degree of vulnerability varies among Purkinje cells, and that this could be related to the uneven loss of these cells. It is proposed that, although this case and cases of ACD have both similarities and differences in their neuropathological aspects, it is apparent that both conditions have some common morphopathogenetic factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687433
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  • 5
    Electronic Resource
    Electronic Resource
    Rupture of a pancreatic pseudocyst into the portal venous system (1999)
    Springer
    Abdominal imaging 24 (1999), S. 494-496 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Pancreatitis—Pseudocyst—Endoscopic retrograde pancreaticocholangiography—Doppler sonography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pseudocyst formation is a well-known complication of acute or chronic pancreatitis. We report a case in which pseudocyst ruptured into the splenic and portal veins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900547
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  • 6
    Electronic Resource
    Electronic Resource
    CT imaging of biliary enteric fistula (1998)
    Springer
    Abdominal imaging 23 (1998), S. 172-176 
    Details
    ISSN: 1432-0509
    Keywords: Key words: CT—Biliary enteric fistula—Pneumobilia—Cholecystoduodenal fistula—Choledochoduodenal fistula—Cholecystocolic fistula.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To define the signs useful for differentiating between gallbladder–enteric fistula (GB-EF) and common bile duct–enteric fistula (CBD-EF) on computed tomography (CT) because the prognosis and management of the two are different. Methods: CT scans in 13 patients with pneumobilia, who had not had surgical biliary–enteric anastomosis and endoscopic sphincterotomy, were reviewed. The presence of fistula itself, the location of air in the biliary system, and the appearance of the gallbladder were assessed. Results: The causes of pneumobilia were GB-EF in seven patients, CBD-EF in three patients, emphysematous cholecystitis (EC) in one patient, gallbladder cancer (GBC) in one patient, and incompetent sphincter of Oddi in one patient. In three of seven GB-EF patients (43%) and in none of the three CBD-EF patients (0%), the fistula itself was detected. Air was detected in the common bile duct in four of seven GB-EF (57%) and in all three CBD-EF (100%) patients, and GBC. In six of seven GB-EF (86%) and in one of three CBD-EF (33%) patients, the gallbladder was contracted. Thus, the location of air and the contraction of gallbladder were useful signs to differentiate GB-EF from CBD-EF. Conclusion: CT can distinguish between GB-EF and CBD-EF.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900314
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  • 7
    Electronic Resource
    Electronic Resource
    A quantitative study of blood-brain barrier permeability ultrastructure in a new rat glioma model (1985)
    Springer
    Acta neuropathologica 67 (1985), S. 96-102 
    Details
    ISSN: 1432-0533
    Keywords: Blood-brain barrier ; Morphometry ; Ultrastructure ; Experimental glioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebral edema, a major complication of tumors in the brain, is the result of an alteration in the blood-brain barrier (B-BB). The vascular ultrastructural changes that underlie edema formation have been described in a variety of tumors. Interendothelial junction abnormalities, fenestrations, and large numbers of tubulo-vesicular profiles in the tumor vascular endothelium have been presumed to represent permeability routes that permit the escape of serum constituents into the tumor, from where they flow into the surrounding brain. Descriptive studies do not provide information on the relative frequency of these presumptive permeability routes. In the study reported here we have quantified ultrastructural features associated with the B-BB in the vessels of an experimental glioma in rat. We found that approximately 60% of the tumor vessel profiles have junctional abnormalities and 30% have one or more fenestrations. The density of tubulo-vesicular profiles, however, was not increased. In addition, tumor vessel walls were thicker than normal vessels of the same caliber and the mitochondrial density was in the range of that for non-barrier vessels. Vessels in peritumoral regions were not altered in any of the parameters measured.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688129
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  • 8
    Electronic Resource
    Electronic Resource
    Microorganism inactivation using high-pressure generation in sealed vessels under sub-zero temperature (1998)
    Springer
    Applied microbiology and biotechnology 50 (1998), S. 415-418 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract In order to test the possibility of utilizing high pressure in bioscience and biotechnology, a simple method for high-pressure generation and its use for microbial inactivation have been studied. When a pressure vessel was filled with water, sealed tightly and cooled to sub-zero temperatures, high pressure was generated in the vessel. The pressure generation was 60 MPa at −5 °C, 103 MPa at −10 °C, and 140 MPa at −15 °C, −20 °C, and −22 °C. The high pressure generated inactivated microorganisms effectively: yeasts (Saccharomyces cerevisiae and Zygosaccharomyces rouxii), bacteria (Lactobacillus brevis and Eschericia coli), and fungi (Aspergillus niger and Aspergillus oryzae) were completely inactivated when stored in sealed vessels −20 °C for 24 h. However, Staphylococcus aureus was only partly inactivated under the same conditions. This method opens up a new application of high pressure for storing, transporting, and sterilizing of foods and biological materials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530051313
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  • 9
    Electronic Resource
    Electronic Resource
    Role of hemolysis in potassium release by iodinated contrast medium (1999)
    Springer
    European radiology 9 (1999), S. 1357-1361 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Iodinated contrast medium ; Adverse effect ; Contrast media toxicity ; Hemolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. It has been demonstrated that an iodinated contrast medium (CM) causes release of potassium into blood vessel lumina, resulting in an increase in serum potassium. The purpose of the present study was to assess whether this potassium release is due to hemolysis. Fresh human blood was mixed in vitro with CM at a ratio of 10:2. Potassium release rates were determined, and serum haptoglobin and free hemoglobin were measured after 30 min of exposure to CM. To compare the potassium release curve between CM exposure and true hemolysis induced by distilled water, fresh human blood was also mixed with distilled water. The level of serum haptoglobin decreased due to hemodilution. Changes in haptoglobin were not correlated with potassium release rates. The serum free hemoglobin level did not increase significantly, and there was no correlation between changes in the free hemoglobin level and the rate of potassium release. Hemolysis caused by water occurred instantaneously, whereas potassium release caused by CM was a slow response, which was linearly correlated with exposure time. Potassium release from blood cannot be explained by hemolysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050848
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  • 10
    Electronic Resource
    Electronic Resource
    Lymphocytic hypophysitis presenting with diabetes insipidus: MR findings (1999)
    Springer
    European radiology 9 (1999), S. 1397-1400 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Pituitary gland ; Lymphocytic hypophysitis ; Lymphocytic adenohypophysitis ; Lymphocytic infundibulo-neurohypophysitis ; Diabetes insipidus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. It has been thought that neurohypophysial involvement manifesting as central diabetes insipidus in lymphocytic hypophysitis is rare. The radiological and clinicopathological features of two cases represent a variant of lymphocytic adenohypophysitis and/or lymphocytic infundibulo-neurohypophysitis are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050855
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