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  • 1
    Publication Date: 2023-08-03
    Language: English
    Type: article , doc-type:article
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  • 2
    Publication Date: 2023-08-14
    Language: English
    Type: conferenceobject , doc-type:conferenceObject
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 21 (1998), S. 119-136 
    ISSN: 1432-0541
    Keywords: Key words. Minimum-area hulls, Star-shaped polygons, Monotone polygons, 3sum-Hardness, Lower bounds, Computational geometry, Design and analysis of algorithms.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. We study some minimum-area hull problems that generalize the notion of convex hull to star-shaped and monotone hulls. Specifically, we consider the minimum-area star-shaped hull problem: Given an n -vertex simple polygon P , find a minimum-area, star-shaped polygon P * containing P . This problem arises in lattice packings of translates of multiple, nonidentical shapes in material layout problems (e.g., in clothing manufacture), and has been recently posed by Daniels and Milenkovic. We consider two versions of the problem: the restricted version, in which the vertices of P * are constrained to be vertices of P , and the unrestricted version, in which the vertices of P * can be anywhere in the plane. We prove that the restricted problem falls in the class of ``3sum-hard'' (sometimes called ``n 2 -hard'') problems, which are suspected to admit no solutions in o(n 2 ) time. Further, we give an O(n 2 ) time algorithm, improving the previous bound of O(n 5 ) . We also show that the unrestricted problem can be solved in O(n 2 p(n)) time, where p(n) is the time needed to find the roots of two equations in two unknowns, each a polynomial of degree O(n) . We also consider the case in which P * is required to be monotone, with respect to an unspecified direction; we refer to this as the minimum-area monotone hull problem. We give a matching lower and upper bound of Θ(n log n) time for computing P * in the restricted version, and an upper bound of O(n q(n)) time in the unrestricted version, where q(n) is the time needed to find the roots of two polynomial equations in two unknowns with degrees 2 and O(n) .
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 26 (2000), S. 197-236 
    ISSN: 1432-0541
    Keywords: Key words. Pocket machining, Tool path generation, Machining graph, Provably good approximation, NP-hardness.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. A fundamental problem of manufacturing is to produce mechanical parts from billets by clearing areas within specified boundaries from the material. Based on a graph-theoretical formulation, the algorithmic handling of one particular machining problem—``zigzag pocket machining''—is investigated. We present a linear-time algorithm that ensures that every region of the pocket is machined exactly once, while attempting to minimize the number of tool retractions required. This problem is shown to be ${\cal N\cal P}$ -hard for pockets with holes. Our algorithm is provably good in the sense that the machining path generated for a pocket with h holes requires at most 5 . . . OPT + 6 . . . h retractions, where OPT is the (unknown) minimum number of retractions required by any algorithm. The algorithm has been implemented, and practical tests for pockets without holes suggest that one can expect an approximation factor of about 1.5 for practical examples, rather than the factor 5 as proved by our analysis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 66 (1988), S. 488-493 
    ISSN: 1432-1440
    Keywords: HIV-1-infection ; Westernblot analysis ; Pattern of antibody response ; Env, core and enzymatic proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The westernblot analysis of 170 patients with HIV-1-infection demonstrated that 47% of the patients in latent stage, 58% of the patients with lymphadenopathy-syndrome and only 25% of the patients with the full-blown picture of AIDS showed the complete pattern of HIV-specific antibody response. This antibody response is mainly directed against the env-encoded envelope proteins gp160, gp120 and gp41, against the gag-encoded core proteins p55, p24 and p17 as well as against the pol-encoded enzymatic proteins p66, p51 and p31. Antibodies against gp160 and gp120 were present in nearly all patients, whereas the prevalence of the other antibodies decreased with the stage of the disease. Statistical significant differences were found particularly between patients with LAS or AIDS respectively. Antibodies against p17 were detected in 74% of the patients with LAS but only in 25% of the patients with AIDS. The lack of antibodies against p17, p24 or p51 was significantly associated with lower mean CD4/CD8-ratios (p〈0,007) and higher mean serum levels of IgA (p〈0,001) and beta-2-microglobulin (p〈0.001). One third of the patients with LAS and this reduced pattern of antibody response developed AIDS within six months. These results demonstrate that the detection of antibodies against p17, p24 or p51 is of prognostic importance. A serological profile which lacks the antibody response against at least two of those three viral antigens indicates a progression of the disease activity.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Economic Psychology 3 (1983), S. 379-394 
    ISSN: 0167-4870
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Psychology , Economics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron 46 (1990), S. 5377-5382 
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    HNO 48 (2000), S. 45-48 
    ISSN: 1433-0458
    Keywords: Schlüsselwörter Extrapulmonal ; Inflammatorischer Pseudotumor ; Nase ; Key words Extrapulmonary neoplasms ; Pseudotumor ; Nasal pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary An inflammatory pseudotumor occurs unifocally and is a benign tumor that was initially described in the lung. In the present case report a 24-year-old woman experienced progressive nasal obstruction because of an abnormallity of the nasal septum. A cauliflower-like tumor of the anterior region of the septum cartilage was seen macroscopically and was completely resected. This was diagnosed histologically as an inflammatory pseudotumor. The literature is reviewed and differential diagnoses discussed. Various therapeutic procedures are noted, but the treatment of choice is complete resection of tumor.
    Notes: Zusammenfassung Der inflammatorische Pseudotumor tritt in der Regel singulär auf und ist ein benigner Tumor, der erstmals in der Lunge beschrieben wurde. Beschrieben wird der Fall einer 24jährigen Frau mit progredienter Nasenatmungsbehinderung infolge einer Verdickung des vorderen Septums. Makroskopisch zeigte sich ein blumenkohlartiger Tumor im Bereich des vorderen Septumknorpels, der vollständig reseziert wurde. Histologisch handelte es sich um einen inflammatorischen Pseudotumor. Anhand eines Überblicks über die relevante Literatur werden Differentialdiagnosen diskutiert. Die Therapie der Wahl besteht in einer vollständigen chirurgischen Resektion des Tumors.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Der Internist 39 (1998), S. 860-865 
    ISSN: 1432-1289
    Keywords: Schlüsselwörter Common Variable Immunodeficiency Syndrom (CVI) ; Rezidivierende bakterielle Infektionen ; Bronchiektasen ; Autoimmunerkrankungen ; Neoplasien
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die Kombination von chronisch rezidivierenden Infektionen der oberen und unteren Atemwege mit Autoimmunerkrankungen, wie im vorliegenden Fall mit einer Vitiligo und einer perniziösen Anämie, sollte an ein Common Variable Immunodeficiency Syndrom denken lassen. Diagnostisch richtungsweisend sind neben dem klinischen Befund stark erniedrigte Immunglobulinserumspiegel. Bei der Diagnostik der Autoimmunerkrankungen muß berücksichtigt werden, daß trotz des klinischen Bildes einer Autoimmunerkrankung nur selten Autoantikörper nachweisbar sind. Therapeutisch steht zur Zeit die effektive Behandlung der Infekte und die kontrollierte Immunglobulinsubstitution im Vordergrund. Für die Prognose der Patienten mit nachgewiesenem Immundefekt sind außerdem regelmäßige Vorsorgeuntersuchungen entscheidend, da auch eine erhöhte Inzidenz an Neoplasien, insbesondere des Magens sowie des lymphatischen Systems, bekannt ist.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Propellants, Explosives, Pyrotechnics 13 (1988), S. 111-119 
    ISSN: 0721-3115
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The maximum depth of penetration, Pmax, of a shaped charge jet can theoretically be calculated from 5 quantities for the purely continuous, or for the initially continuous and then particulated, or for the fully particulated penetrating jet. These quantities are the distance Z0 of the target plate from the virtual origin, the value of γ (i.e. the square root of the ratio of target to jet density), the jet tip velocity vj,0 the efficient residual velocity vj,min, and the particulation time tp.Instead of calculating the individual values of vj,min for the individual depths of penetration Pexp at various standoff distances, this quantity can quite simply be read from the standoff diagram by means of the penetration cutoff lines- a so-called Standoff/Cutoff-diagram -, using the experimentally determined depth of penetration Pexp. The penetration cutoff lines are lines which start at the virtual origin and which represent the ideal increment in depth of penetration per jet velocity interval in the standoff diagram, the abscissas of this line corresponding to the jet tip velocities.The methods are demonstrated and explained, using the results of three firings with one type of shaped charge as an example. The shots were made at 6, 12, and 24 calibers standoff distance, and the cratering history was also determined in these trials.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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