ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Long-term studies in the non-human primate Papio ursinus were set to investigate theinduction of bone formation in biphasic hydroxyapatite tricalcium phosphate (HA/TCP) biomimeticmatrices, 20/80 and 40/60, respectively. Biomimetic matrices were implanted in the rectusabdominis and in calvarial defects of 4 adult Papio ursinus. Morphological analyses on day 90 and365 showed significant induction of bone formation within concavities of the biomimetic matricesimplanted in both heterotopic and orthotopic sites with resorption of the implanted biomimeticmatrices. The smart biomimetic matrices induced de novo bone formation even in the absence ofexogenously applied osteogenic proteins of the transforming growth factor-β superfamily
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.981.pdf
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