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  • 1
    Electronic Resource
    Electronic Resource
    Antigen-specific augmentation factor involved in murine delayed-type footpad reaction (1987)
    Springer
    Medical microbiology and immunology 176 (1987), S. 229-239 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We previously found an antigen-specific factor capable of augmenting delayed-type hypersensitivity (DTH) in the culture supernatant of the mixture of immune spleen cells and erythrocyte antigen, or in the serum of mice immunized with heterologous erythrocytes and exhibiting delayed-type footpad reaction. To elucidate whether this kind of factor (DTH-augmentation factor; DAF) participates in the establishment of DTH to various kinds of antigen besides erythrocyte antigen, we chose a bacterial antigen, Listeria monocytogenes, which is a facultative intracellular bacterium. In the present study, we demonstrated that the immune serum from mice immunized with viable Listeria augmented the delayed-type footpad reaction to Listeria. Furthermore, acquired resistance against Listeria was also augmented by the transfer of such immune serum. Such augmentation of acquired resistance was observed in sites infected locally and in the spleen of mice infected systemically. This effect was also seen in sera from mice immunized with heat-killed Listeria emulsified with complete Freund's adjuvant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190529
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Vitamin A and tumor immunity (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 92-93 
    Details
    ISSN: 1420-9071
    Keywords: Mouse, BALB/c ; fibrosarcoma Meth A ; vitamin A, tumor rejection ; lymphocytes, cytotoxic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Intraperitoneal administration of vitamin A into the BALB/c mice inoculated with a syngeneic fibrosarcoma, Meth A, caused a remarkable augmentation of tumor rejection. A cell-depletion technique revealed that the primary effector cells responsible for the augmented rejection were Thy-1 positive, Lyt-1 negative, Lyt-2 positive lymphocytes, suggesting the involvement of cytotoxic lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02005892
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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