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  • 1
    Electronic Resource
    Electronic Resource
    Voltage gating in VDAC is markedly inhibited by micromolar quantities of aluminum (1987)
    Springer
    The journal of membrane biology 99 (1987), S. 187-196 
    Details
    ISSN: 1432-1424
    Keywords: membrane ; aluminum ; channel ; mitocondrion ; voltage dependence ; VDAC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The mitochondrial outer membrane contains voltagegated channels called VDAC that are responsible for the flux of metabolic substrates and metal ions across this membrane. The addition of micromolar quantities of aluminum chloride to phospholipid membranes containing VDAC channels greatly inhibits the voltage dependence of the channels' permeability. The channels remain in their high conducting (open) state even at high membrane potentials. An analysis of the change in the voltage-dependence parameters revealed that the steepness of the voltage dependence decreased while the voltage needed to close half the channels increased. The energy difference between the open and closed states in the absence of an applied potential did not change. Therefore, the results are consistent with aluminum neutralizing the voltage sensor of the channel. pH shift experiments showed that positively charged aluminum species in solution were not involved. The active form was identified as being either (or both) the aluminum hydroxide or the tetrahydroxoaluminate form. Both of these could reasonably be expected to neutralize a positively charged voltage sensor. Aluminum had no detectable effect of either single-channel conductance or selectivity, indicating that the sensor is probably not located in the channel proper and is distinct from the selectivity filter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01995699
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  • 2
    Electronic Resource
    Electronic Resource
    Transatlantic Movement of a Tagged Spurdogfish (1967)
    [s.l.] : Nature Publishing Group
    Nature 214 (1967), S. 1140-1141 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is clearly impossible to state the route that this fish took, but it would have belonged to the Scottish Nor-wegian stock, which reaches the Faeroes, although fish of this stock normally migrate between Scotland and Norway. Another spurdogfish from this stock, tagged north of Scotland (60 06' ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2141140b0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Significance of Sexual Dimorphism of the Anal Fin of Polypteridae (1971)
    [s.l.] : Nature Publishing Group
    Nature 232 (1971), S. 135-136 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 Size of Testes Taken from Po/ypterus Total length (mm) Fish Total weight (g) Length (mm) Right testis Maximum width (mm) Length (mm) Left testis Maximum width (mm) Total testes weight (g) P. bichir 515 880 21 7 29 5 0.67 434 435 42 5 43 4 0.44 P. endlicheri ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/232135b0
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