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  • 1
    Electronic Resource
    Electronic Resource
    Infection with Staphylococcus aureus producing toxic shock syndrome (TSS) toxin-1 without TSS (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 318-319 
    Details
    ISSN: 1432-1076
    Keywords: Toxic shock syndrome ; Antibody response ; Symptoms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Relevant findings are reported in an 8-year-old boy with skin infection due to Staphylococcus aureus producing toxic shock syndrome toxin-1 without shock but with an increase in antibody titre against the toxin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444123
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  • 2
    Electronic Resource
    Electronic Resource
    Neonatal metatarsus adductus, joint mobility, axis and rotation of the lower extremity in preterm and term children 0–5 years of age (1988)
    Springer
    European journal of pediatrics 148 (1988), S. 19-23 
    Details
    ISSN: 1432-1076
    Keywords: Metatarsus adductus ; Axis ; Rotation ; Lower extremity ; Children, term and preterm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 484 premature children and a control group of 114 healthy term children underwent orthopaedic follow-up from birth to 5 years of age. At birth, metatarsus adductus was found to be more frequent in twins than in single infants (41% vs 16%; P〈0.01), but occurred with equal frequency in single preterm and term infants (16% vs 12%). By 5 years of age, metatarsus adductus had resolved in all the term but only in 81% of the preterm children (P〈0.05). In the preterm and term groups, knee axis (mean intermalleolar distance 22.0 mm vs 20.1 mm), tibial torsion (mean angle-1.2° vs +0.6°) and angle of gait (mean angle +1.5° vs +0.7°) at 5 years were statistically insignificant. Hip function at 5 years was similar in normal preterm and term children but significantly decreased in preterm children with cerebral palsy, more so with regard to abduction (56° vs 39°, P〈0.05) and extension (22° vs 8°, P〈0.01). The difference between the sexes was insignificant in both the preterm and term groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441806
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  • 3
    Electronic Resource
    Electronic Resource
    Mother-to-child transmission of human immunodeficiency virus type 1: Influence of parity and mode of delivery (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 542-545 
    Details
    ISSN: 1432-1076
    Keywords: HIV infections ; Infant newborn ; Pregnancy ; Parity ; Caesarean section
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abstract In a national prospective study of risk factors for mother-tochild transmission of human immunodeficiency virus (HIV), 316 children of HIV-positive mothers were followed up for at least 6 months. Infection status was determined in 254 of them and 46 were found to be infected giving a transmission rate of 18.1%. Univariate analysis of potential risk factors for mother-to-child transmission showed an association between primiparity and increased transmission rate: odds ratio 2.2, 95% confidence interval (CI) 1.1–4.6,P〈0.05. Analysis by logistic regression confirmed this association (adjusted odds ratio 2.4) and showed, in addition, a negative association between transmission rate and elective Caesarean section (adjusted odds ratio 0.36, 95% CI 0.13–0.97,P〈0.05). The effect of primiparity was less pronounced in combination with elective Caesarean section (odds ratio 1.7) than with other delivery modes (odds ratio 2.5, difference not significant. HIV-infected children were less likely to experience the birth of a younger sibling during the observation period than their uninfected counterparts (2 of 46 vs 27 of 208,P〈0.05 by logrank test). Conclusions Primiparous women appear to transmit HIV to their children at a higher rate. This could be explained by increased intrapartum transmission because of longer and more complicated labour in primiparas and/or by a self-selection of women with lower risk of transmission among those deciding to have additional children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02074831
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  • 4
    Electronic Resource
    Electronic Resource
    Compensatory maturational deceleration of growth or “catch-down growth” in patients with congenital adrenal hyperplasia after delayed initiation of therapy (1986)
    Springer
    European journal of pediatrics 144 (1986), S. 550-553 
    Details
    ISSN: 1432-1076
    Keywords: Congenital adrenal hyperplasia ; Growth ; Delayed treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The growth pattern is reported of 16 patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency in whom therapy was started after the age of 3 years. Treatment was initiated at a mean chronological age (CA) of 4.7 years (range 3.0–7.2) and at a mean bone age (BA) of 10.4 years (range 10.2–13.2). It consisted of hydrocortisone (mean dosage 26 mg/m2) or prednisone (8.7 mg/m2) in all, and of fluorohydrocortisone (0.05–0.1 mg daily) in five patients. At the last examination the mean duration of therapy was 5.2 years, the mean CA 10.0 years, and the mean BA 12.6 years. In 13 of the 16 patients a “catch-down growth” pattern was observed, which was characterised by a decrease in height (expressed, as SDS) for CA, a deceleration of bone maturation and increase of height (SDS) for BA, and an improvement in predicted height (Bayley-Pinneau).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496033
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  • 5
    Electronic Resource
    Electronic Resource
    Infants born to mothers with antibodies againstBorrelia burgdorferi at delivery (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 426-427 
    Details
    ISSN: 1432-1076
    Keywords: Borrelia burgdorferi ; Pregnancy ; Infection ; Infant outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A serological survey over a 1-year period of 1416 mothers at delivery and their 1434 offspring for the presence of anti-Borrelia burgdorferi antibodies revealed a prevalence of 0.85%. Clinically active Lyme disease during pregnancy was found in 1 of these 12 women with elevated titres and the child was born with a ventricular septal defect. Of six affected children, two had hyperbilirubinaemia, one muscular hypotonia, one was underweight for gestational age, one was macrocephalic, and one had supraventricular extrasystoles. Anomalous findings could not be attributed toB. burgdorferi due to a lack of serological evidence of intrauterine infection. Our data do not imply the need for serological screening in pregnancy, however, the importance of recognition and treatment of Lyme disease in pregnancy is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00595903
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  • 6
    Electronic Resource
    Electronic Resource
    Pericardial effusion as a sign of acquired hypothyroidism in children with Down syndrome (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 397-398 
    Details
    ISSN: 1432-1076
    Keywords: Pericardial effusion ; Hypothyroidism ; Down syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In three children with Down syndrome and acquired hypothyroidism echocardiography was performed before and after the start ofl-thyroxine treatment. Initial studies revealed pericardial effusions which resolved during treatment suggesting that they were caused by hypothyroidism. The incidence of hypothyroidism in Down syndrome is high, but the diagnosis is often missed for lack of specific clinical criteria. The finding of pericardial effusion by echocardiography may be essential in discovering thyroid dysfunction. The cases illustrate that regular thyroid function tests are important in Down syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955895
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  • 7
    Electronic Resource
    Electronic Resource
    Stable human immunodeficiency virus encephalopathy in two infants receiving early intravenous gammaglobulin plus antimicrobial prophylaxis (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 417-422 
    Details
    ISSN: 1432-1076
    Keywords: HIV ; Encephalopathy ; Infant ; IVGG ; Followup
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two infants with human immunodeficiency virus (HIV) infection, encephalopathy, intrathecal anti-HIV IgG antibody production and (in one case) the presence of HIV antigen received monthly doses of intravenous gammaglobulin (IVGG) and daily antimicrobial prophylaxis starting at the ages of 6 and 9 months respectively. The follow-up over 15 and 12 months revealed a favourable course with remarkable improvement in visuo-spatial functions, receptive language, play behaviour and fine motor skills, as well as in muscle tone, pyramidal tract signs and vigilance in case 1, and near normalization in case 2. Viability of HIV in peripheral blood mononuclear cells, antigen in serum and cellular immunodeficiency, however, all remained unchanged. We suggest that neurological complications of encephalopathy in paediatric acquired immunodeficiency syndrome may have a slower progression when IVGG treatment plus antimicrobial prophylaxis is started early.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00595901
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  • 8
    Electronic Resource
    Electronic Resource
    Pseudotumour cerebri after varicella (1998)
    Springer
    European journal of pediatrics 157 (1998), S. 904-906 
    Details
    ISSN: 1432-1076
    Keywords: Key words Varicella ; Pseudotumour cerebri ; Anti-protein S auto-antibody
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thrombotic complications in children with varicella are well known. Transient protein S deficiency due to the presence of an anti-protein S antibody seems to be responsible at least in part. In an 8-year-old girl, pseudotumour cerebri with abducens palsy and ileofemoral vein thrombosis occurred 3 weeks after chickenpox. A transient elevation of anti-protein S auto-antibodies was identified. Under treatment with heparin the pseudotumour cerebri rapidly disappeared but the iliofemoral thrombosis persisted. Conclusion Thrombotic complications after varicella might be mediated at least in part by antibodies against protein S. Early recognition of this condition permits appropriate treatment with recombinant tissue-type plasminogen activator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050964
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  • 9
    Electronic Resource
    Electronic Resource
    Neurological outcome in high risk weight appropriate for gestational age preterm children at early school age (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 835-844 
    Details
    ISSN: 1432-1076
    Keywords: Preterm children ; Neurological development ; Cerebral palsy ; 5–6 Years of age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Neurological development in preterm children with birth weight appropriate for gestational age is reported in two separate groups: a longitudinal study of 97 preterm children and 93 term children as a control group and a cross-sectional study of 249 preterm children. Both preterm groups were regarded as high risk with respect to number of outborns, distribution of gestational age and perinatal risk factors. Neurological outcome at 5–6 years of age in the majority of the preterm children was comparable to that of the term children. However, 15% of boys and 9% of girls in the preterm group were diagnosed as having cerebral palsy. Mild diplegia was most frequently observed; 4% of the children were severely impaired. Fourteen percent of the preterm vs 2% of the term boys and 6–9% of the preterm vs none of the term girls received motor therapy during early school age. There was a small but consistent sex difference in neurological outcome in favour of the term and preterm girls. Effects of drop out rate and of incompleteness of ascertainment are reported in detail.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02072070
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  • 10
    Electronic Resource
    Electronic Resource
    Effects of treatment with mineralocorticoids on late steps of aldosterone biosynthesis in the rat
    Amsterdam : Elsevier
    Journal of Steroid Biochemistry 8 (1977), S. 1-7 
    Details
    ISSN: 0022-4731
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-4731(77)90209-6
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