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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 205 (1994), S. 1291-1298 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Cell Differentiation and Development 27 (1989), S. 57-68 
    ISSN: 0922-3371
    Keywords: Embryonic development, fish ; Gene expression ; Medaka ; Microinjection ; Transgenic fish ; δ-Crystallin gene
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 10 (1971), S. 2574-2581 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1279-8517
    Keywords: Skull ; Craniometry ; Anthropology ; 3-D image ; Helical CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To make a digital image database of human craniology, we optimized the three-dimensional (3-D) images of 29 dried human skull specimens by helical computed tomography (CT). For the verification of the quantitative exactitude of these image data, we manually measured nine items of direct distances between standard anthropologic points on each skull and the corresponding distances projected on the CT monitor by specifying the respective points. The results obtained by the two methods of manual and CT measurements were compared and statistically analyzed. The CT measurements were so exact that the lower limit of correlation coefficients (95% of the confidence interval) between the two results was more than 0.8 in six items; i.e., maximal cranial length and breadth, minimal frontal breadth, bizygomatic breadth, distance between ectomolares and nasion-basion length. In contrast, the CT results were less well correlated with the manual measurements of three items; i.e., distance between bilateral mastoidales, total facial height, and nasal breadth. We concluded that the qualitative representation of 3-D CT images was adequate, although some quantitative data may be incorrect. The inaccuracy is suspected to be due to the difficulty in specifying the standard points on the CT images, and due to the differences in measurement procedures between the direct and projected distances.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1279-8517
    Keywords: Skull ; Craniometry ; Anthropology ; 3-D image ; Helical CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Afin d'établir une banque informatisée de données en crâniologie humaine, nous avons recueilli les images tridimensionnelles, de 29 crânes secs, obtenues par scanner hélicoïdal. Pour vérifier les données obtenues, nous avons mesuré manuellement 9 longueurs situées entre les repères crâniologiques classiques sur chaque crâne et les distances correspondantes entre les points analogues sur la console du scanner. Les résultats obtenus par les 2 méthodes de mesure manuelle et par scanner sont comparés et analysés statistiquement. Les mesures scanner sont situées à la limite inférieure de corrélation entre les 2 résultats (95% d'intervalle de confiance) et supérieures à 0.8 dans 6 mesures : la longueur et la largeur maximales crâniennes, la largeur minimale frontale, la largeur bizygomatique, la distance entre les faces externes des molaires et la longueur nasion-basion. Par contre, les mesures scanner sont moins concordantes avec les résultats manuels dans 3 mesures : distance intermastoïdienne, hauteur faciale totale et largeur nasale. Nous en concluons que la représentation qualitative des images scanner est correcte, même si quelques données chiffrées sont imprécises. Les causes d'erreurs sont, semble t-il, dues à la difficulté de repérer les points crâniologiques précis sur les images scanner, ainsi qu'à la différence des techniques de mesure entre une donnée directe et une en projection.
    Notes: Summary To make a digital image database of human craniology, we optimized the three-dimensional (3-D) images of 29 dried human skull specimens by helical computed tomography (CT). For the verification of the quantitative exactitude of these image data, we manually measured nine items of direct distances between standard anthropologic points on each skull and the corresponding distances projected on the CT monitor by specifying the respective points. The results obtained by the two methods of manual and CT measurements were compared and statistically analyzed. The CT measurements were so exact that the lower limit of correlation coefficients (95% of the confidence interval) between the two results was more than 0.8 in six items; i.e., maximal cranial length and breadth, minimal frontal breadth, bizygomatic breadth, distance between ectomolares and nasion-basion length. In contrast, the CT results were less well correlated with the manual measurements of three items; i.e., distance between bilateral mastoidales, total facial height, and nasal breadth. We concluded that the qualitative representation of 3-D CT images was adequate, although some quantitative data may be incorrect. The inaccuracy is suspected to be due to the difficulty in specifying the standard points on the CT images, and due to the differences in measurement procedures between the direct and projected distances.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0428
    Keywords: Key words Animal models NIDDM, insulin secretion, insulin mRNA, cytochrome b mRNA, islets of Langerhans.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Animals with NIDDM display abnormal glucose regulation of insulin secretion and biosynthesis. We tested reversibility of abnormal regulation by normoglycaemia using an islet transplantation technique. Inbred non-diabetic and neonatally STZ diabetic rats (n-STZ) were used. Transplantations insufficient to normalize the blood glucose levels (200 islets under kidney capsule) were performed from diabetic to normal (D-N) and from diabetic to diabetic (D-D), as well as from normal to normal (N-N) and from normal to diabetic (N-D) rats. Four weeks after transplantation, graft bearing kidneys were isolated and perfused with Krebs-Henseleit bicarbonate buffer to measure insulin secretion in response to 27.8 mmol/l glucose and 10 mmol/l arginine. Four weeks of normoglycaemia failed to restore glucose-induced insulin secretion from n-STZ islets (glucose induced increment: −1.7± 2.5 fmol/min in D-N, 1.2±7.1 fmol/min in D-D). In contrast to normal islets, normoglycaemia reduced insulin mRNA contents (60±24 in D-N, 496±119 in D-D; O. D.-arbitrary units). However, arginine-induced secretion was markedly enhanced by diabetic environment in both normal and n-STZ islet grafts. These results indicate that selected aspects of glucose recognition are irreversibly damaged by a long-term diabetic state or, alternatively, by a lasting effect of STZ administration. [Diabetologia (1994) 37: 351–357]
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0428
    Keywords: Animal models NIDDM ; insulin secretion ; insulin mRNA ; cytochrome b mRNA ; islets of Langerhans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Animals with NIDDM display abnormal glucose regulation of insulin secretion and biosynthesis. We tested reversibility of abnormal regulation by normoglycaemia using an islet transplantation technique. Inbred non-diabetic and neonatally STZ diabetic rats (n-STZ) were used. Transplantations insufficient to normalize the blood glucose levels (200 islets under kidney capsule) were performed from diabetic to normal (D-N) and from diabetic to diabetic (D-D), as well as from normal to normal (N-N) and from normal to diabetic (N-D) rats. Four weeks after transplantation, graft bearing kidneys were isolated and perfused with Krebs-Henseleit bicarbonate buffer to measure insulin secretion in response to 27.8 mmol/l glucose and 10 mmol/l arginine. Four weeks of normoglycaemia failed to restore glucose-induced insulin secretion from n-STZ islets (glucose induced increment:-1.7±2.5 fmol/min in D-N, 1.2±7.1 fmol/min in D-D). In contrast to normal islets, normoglycaemia reduced insulin mRNA contents (60±24 in D-N, 496±119 in D-D; O.D.-arbitrary units). However, arginine-induced secretion was markedly enhanced by diabetic environment in both normal and n-STZ islet grafts. These results indicate that selected aspects of glucose recognition are irreversibly damaged by a long-term diabetic state or, alternatively, by a lasting effect of STZ administration.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0509
    Keywords: Key words: Behçet's disease−Aneurysm−Renal artery−Trancatheter arterial embolization−Computed tomography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We describe a patient with Behçet's disease who developed multiple aneurysms and retroperitoneal hemorrhage due to rupture of a renal artery aneurysm. Despite successful transcatheter arterial embolization, the patient died due to pneumonia. Our retrospective review of the case revealed that the CT scan obtained 3 months before the rupture had demonstrated dilatation of bilateral renal arteries.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 23 (1998), S. 158-160 
    ISSN: 1432-0509
    Keywords: Key words: Angiomyolipoma—Liver—MRI— CT—US.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A case of hepatic angiomyolipoma and its imaging features are presented. Computed tomography of the liver showed a low-density mass without obvious fat. T1-weighted magnetic resonance images revealed a low-signal-intensity mass containing some tiny high-signal-intensity foci. One of the high-signal-intensity foci was found by histology to represent the fat component of the tumor.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0533
    Keywords: Myotonic dystrophy ; Intracytoplasmic inclusion bodies ; Marinesco bodies ; Thalamus ; Substantia nigra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intracytoplasmic inclusion bodies of the thalamus and the substantia nigra, and Marinesco bodies have been studied in four patients with myotonic dystrophy (MyD), eight patients with other neurological diseases (control A), and eight patients without neurological diseases (control B). The percentages of the affected cells were calculated by dividing the number of neurons including intracytoplasmic inclusion bodies of the thalamus and the substantia nigra, and Marinesco bodies, by the total cell count in these respective regions. Statistical analyses were performed with regard to the frequency of these bodies by using Student'st test. There was a significantly higher incidence of intracytoplasmic inclusion bodies of the thalamus (13.2% versus 0.7%,P〈0.001) and the substantia nigra (20.4% versus 2.7%,P〈0.001), and Marinesco bodies (37.4% versus 4.1%,P〈0.001) in patients with MyD than in controls A and B. From our observations, it is suggested that the presence with a high frequency, in combination, of these bodies is not an incidental finding but may have an intimate and important relationship with the pathogenesis of MyD, and may be a conspicuous and diagnostically important feature of MyD.
    Type of Medium: Electronic Resource
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