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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 117 (1992), S. 66-69 
    ISSN: 0942-0940
    Keywords: Abducens nerve ; extraocular muscles ; intra-operative monitoring ; nerve injury ; oculomotor nerve ; skull base surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A ring-shaped electrode was developed and used in 20 patients to record evoked electromyographic responses directly from the extraocular muscles during skull base surgery. Intra-operative monitoring with this electrode helps the surgeon to localize the nerves that innervate the extraocular muscles precisely and to refrain from disturbing important neural structures during operations. Such monitoring also provides some insight into the pathophysiology of the dysfunction of these nerves resulting from skull base lesions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 125 (1993), S. 161-168 
    ISSN: 0942-0940
    Keywords: Biobond® ; cerebral aneurysm ; coating ; liquid cellulose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have developed a new coating material for cerebral aneurysms consisting of cellulose. The possible usefulness of this ethyl cellulose — ethyl acetate solution (“Liquid cellulose”) as a coating material was evaluated as follows: 1) The liquid cellulose (ethyl cellulose concentration, 10%; degree of polymerization, 100) and Biobond® had pHs of 7.35 and 3.16, and viscosities of 1,385 and 626 cp, respectively. The properties of the coat (N=30, M±SD) of the liquid cellulose and Biobond® at a cast coat thickness of 254 μm were as follows: coat thickness after drying (μ), 17.8±2.8 and 109.8±44.2; coat formation time (sec), 62 and 1,800; strength of the coat (gm), 432.3±51.4 and 8.0±5.6; strength index (kg/cm2), 572.8±84.7 and 2.4±1.8; and elongation index (%), 14.8±3.5 and 705±188.8, respectively. The coat using liquid cellulose was more physiological and far stronger. It was also more readily manipulated during the operation than Biobond®. 2) The liquid cellulose showed excellent adhesiveness when applied to the vascular wall. Sequential histological observations for 12 months showed that the liquid cellulose remained stable without histotoxicity or cracks in the coat. These results indicate the potential usefulness of this agent for reinforcing the vascular wall.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 45 (1979), S. 343-343 
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 43 (1978), S. 101-110 
    ISSN: 0942-0940
    Keywords: Dural arteriovenous malformation (dural AVM) ; false aneurysm ; exophthalmos
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of dural arteriovenous malformation with giant non-traumatic false aneurysm in the left middle fossa is reported. A 10-year-old female patient was admitted to our hospital with pulsating exophthalmos of the left eye, which was successfully treated by ligation of the main feeder and finally by the radical excision of the dural AVM and false aneurysm. False aneurysm of non-traumatic origin is so rare that only two cases were detected in the literature (Reinaet al., Sakakiet al.), and no previous case of false aneurysm complicated by dural AVM seems to have been reported.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0942-0940
    Keywords: Macrophage ; subarachnoid haemorrhage (SAH) ; subarachnoid fibrosis ; scanning electron microscope (SEM)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixty dogs with experimental subarachnoid haemorrhage (SAH), repeated SAH, and subarachnoid fibrosis (examined three weeks and three months after SAH, and treated with urokinase or dexamethasone) were examined by scanning electron microscope (SEM). The authors observed the resting and activated macrophages, the erythrophagocytosis, and giant cells in the subarachnoid space after SAH. They consider that the macrophages play an important role in the formation of subarachnoid fibrosis, similar to the role of macrophages in fibrosis in other sites.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 74 (1985), S. 134-140 
    ISSN: 0942-0940
    Keywords: Gangliocytoma ; pineal body ; “sea lion” position (operative position) ; CT ; brain scintiscan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ganglion cell tumours are mostly seen in children and young people, but they are extremely rare, accounting for 0.1–0.5% of all brain tumours. It usually occurs in the floor of the third ventricle and the temporal lobe. Recently we have experienced a pineal gangliocytoma, probably the first ever seen in Japan and the fourth case in the world, and have succeeded in a total removal of it. The case concerns a 51-year-old man who sufferend from intermittent blurred vision and headache of 3 years' duration. CT showed, together with severe hydrocephalus, positive contrast medium enhancement and a somewhat irregular but sharply circumscribed high density lesion suggestive of a meningioma. But the brain scintiscan revealed a badly and irregularly demarcated region of warm activity and having little change with time mainly in the pineal region, which was strongly suspicious of gliomas. Hence this scan was thought to be important in diagnosing this tumour. As an operative procedure, biparieto-occipital craniotomy was successfully performed in the “sea lion” position to remove the tumour totally. Pathological findings indicated a mixture of dispersion and concentration of giant cells possessing prominent nucleoli, abundant chromatin and a prominent nucleus or several nuclei of varying sizes and process-like cell bodies polygonal or irregular in shape. GFAP stain showing no glial fibres and the tumour was thought to be a gangliocytoma.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0942-0940
    Keywords: Non-ionic contrast media ; water soluble contrast media ; ventriculography ; cisternography ; myelography ; DIG
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A non-ionic water soluble contrast medium, 3-Deoxy-3-Iodo-d-Glucose (DIG), was experimentally evaluated for use in the cerebrospinal fluid (CSF) space, and compared with other contrast media. Two ml (180 mgI/ml) of DIG were injected either intraventricularly or intracisternally in 15 adult mongrel dogs (average weight: 6.4 kg), and X-ray photographic, CSF, EEG, and histological studies were then performed. Additional tests were made on four beagle dogs (average weight: 9.8 kg), focussing particularly on changes in cell count and protein in the CSF following alternate intracisternal injections of 2 ml (170 mgI/ml) of DIG and metrizamide (Amipaque®), and on epileptogenicity following intracisternal injection of 3 ml (300 mgI/ml)of DIG. That DIG provides adequate definition was demonstrated both by the ventriculograms and cisternograms, and by comparison with metrizamide. Neither epileptic discharges in the EEG nor epileptic symptoms were seen in any of the dogs used in the studies. In the CSF drawn 24 hours after the injection, protein tended to increase moderately with DIG, but pleocytosis was mild with both media. Histological studies of the central nervous system structures around the cisterna magna revealed no definite abnormal findings. Neither fibrosis nor arachnoid adhesions were seen in scanning electron microscopic observations of the basal subarachnoid spaces.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 122 (1993), S. 49-53 
    ISSN: 0942-0940
    Keywords: Cranioplasty ; dynamic CT scan ; neurological signs ; external decompression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors studied the changes in neurological signs and cerebral circulation by using dynamic CT scans before and after cranioplasty in six externally decompressed patients. Five of the 6 patients showed some improvements in neurological signs. The results of the dynamic CT scans in 6 cases suggested that increases of bilateral cerebral blood flow may play a role in their neurological improvement.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 106 (1990), S. 153-159 
    ISSN: 0942-0940
    Keywords: Middle cerebral artery aneurysm ; risk factor ; aneurysmal morphology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Influences of various factors on postoperative outcome of 122 well-documented cases, out of a total of 151 cases of middle cerebral artery aneurysm, are discussed in this paper. The shape of the aneurysm, major axis, major axis/neck and major/minor axis ratio were correlated with the presence or absence of a bleb (p 〈 0.0000001), and indicated a correlation not only between aneurysmal shape and the outcome (p 〈 0.05) but also between preoperative seriousness and the outcome (p 〈 0.05). The preoperative seriousness and the grade of subarachnoid haemorrhage indicated a close correlation between each of these two parameters and the outcome (p 〈 0.000001 for each). Both the quantity and the colour of CSF outflow from the chiasmal cistern showed close correlation with vasospasm (p 〈 0.01), onset of hydrocephalus (p 〈 0.01) and the outcome (p 〈 0.001). Moreover, vasospasm and hydrocephalus grade itself also showed close correlation with the outcome (p 〈 0.001 and p 〈 0.00001). All parameters: blood pressure grade, BPmax, BPmin, BP fluctuation showed correlations not only with preoperative seriousness (p 〈 0.001) and the outcome (p 〈 0.0001) but also with subarachnoid haemorrhage frequency, number of aneurysms, and major axis/neck ratio.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0942-0940
    Keywords: Subarachnoid fibrosis ; subarachnoid haemorrhage (SAH) ; tranexamic acid ; antifibrinolytic therapy ; scanning electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of antifibrinolytic therapy on posthaemorrhagic subarachnoid fibrosis was observed experimentally in dogs with the scanning electron microscope (SEM). The subchronic subjects, given intravenous injections of tranexamic acid (1 mg/day) for 12 days and sacrificed 3 weeks after cisternal blood injection, showed residual clot with thick fibrosis, especially around the haemorrhage. The chronic subjects, to which the same procedure was applied and which were sacrificed three months after cisternal blood injection, showed significant increases in the subarachnoid fibrosis, most remarkably in the parasagittal region. Tranexamic acid is widely used for preventing the recurrence of subarachnoid haemorrhage. However, it was revealed in this study that antifibrinolytic therapy might increase chronic posthaemorrhagic subarachnoid fibrosis, which is considered to be responsible for communicating hydrocephalus by disturbing epicortical CSF flow4.
    Type of Medium: Electronic Resource
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