ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Unidirectional porous hydroxyapatite (UDPHAp) was developed which has microstructure in that cross sectionally oval pores 100 ~ 300µm in diameter penetrate through the material, and that is suitable for osteogenesis and angiogenesis.The porosity of the UDPHAp was 75 % and the compression strength was 14 MPa. A cortical bone defect was made at proximal tibia of Japanese white rabbit, and a trapezoidal prisms shaped UDPHAp was implanted. By histlogical evaluation, 2 weeks after implantation, new bone and new capillary was observed inside UDPHAp. Twelve weeks after implantation, new bone formation was observed in 41.6 % of the porous area. The results of this study suggest a great possibility of utilizing it in actual clinical setting as a bone substitution
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.396-398.11.pdf
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