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  • 1
    Electronic Resource
    Electronic Resource
    Ontogeny of NADPH-diaphorase in rat forebrain and midbrain (1998)
    Springer
    Anatomy and embryology 197 (1998), S. 229-247 
    Details
    ISSN: 1432-0568
    Keywords: Key words NOS ; Histochemistry ; Prenatal ; Postnatal ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This study characterizes the developmental expression of NADPH-diaphorase from embryo to adulthood in the forebrain, midbrain and cerebellum of rat brain via histochemical staining. On embryonic day 12 no neurons stained. Labeling was observed in certain nuclei from E15 through the postnatal period to adulthood. Labeling in neurons increased or maintained a constant level with increased age. The embryo demonstrated substantial labeling in neurons of the caudate putamen, bed nucleus of the stria terminalis, preoptic area, lateral hypothalamic area, paraventricular thalamic nucleus, ventromedial hypothalamic nucleus, magnocellular nucleus posterior commissure, and periaqueductal central gray. Additional neuronal labeling was observed postnatally in the olfactory bulb, cerebral cortex, amygdala, various nuclei of the thalamus, interpeduncular nucleus, linear nucleus of the raphe, pretectal area and superior colliculus. In the cerebellum, labeling appeared only after P14 in cells of the molecular cell layer and granular cell layer. The sizes of labeled neurons developed significantly from P4 to P14 in several nuclei. The distinctive temporal and spatial expression pattern of NADPH-diaphorase implies that the NO/cGMP system may play an important role in physiological and developmental functions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004290050134
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  • 2
    Electronic Resource
    Electronic Resource
    Infantile spasms: Etiological factors, clinical aspects, and long term prognosis in 200 cases (1981)
    Springer
    European journal of pediatrics 135 (1981), S. 239-244 
    Details
    ISSN: 1432-1076
    Keywords: Infantile spasms ; Etiological factors ; Clinical aspects ; Long term prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The etiological factors, clinical aspects and long term prognosis were studied in 200 patients with infantile spasms. Forty-eight (24.0%) died and the rest were aged 6 years or more at the time of final follow-up. In 73 (36.5%) the etiology was prenatal, in 44 (22.0%) perinatal, and in 17 (8.5%) postnatal: 18 cases (9.0%) were cryptogenic. The remaining 48 (24.0%) patients were doubtful cases. The mortality of the pre-and perinatal cases at 35.6% and 34.1% respectively was significantly higher than that in the other etiologic groups (P〈0.001). With regard to the onset of spasms, these were very carly in the pre-and perinatal groups, whereas in the postnatal group the onset was late. The onset in the doubtful and cryptogenic groups was in between. Some 44.4% of the cryptogenic cases showed normal mental and physical development after the age of 6 years, whereas less than 10% of the prenatal and perinatal group did so. Almost all of the doubtful cases became mentally subnormal. The incidence of a family history of epilepsy or other convulsive disorders in the first, second and third degree relatives was highest in the cryptogenic cases (40.0%), and lowest in the perinatal cases (9.3%) (P〈0.01). The incidence of laughing attacks was highest in the postnatal cases (42.9%), against no such attacks in cryptogenic cases (P〈0.01). The attacks seemed to be linked with organic brain lesions. Among various factors related to the etiology of infantile spasms, genetic propensity seemed especially important in cryptogenic cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442097
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  • 3
    Electronic Resource
    Electronic Resource
    FATIGUE LIFE AND SURFACE CRACK PENETRATION BEHAVIOUR OF AN ALUMINIUM ALLOY (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 18 (1995), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Fatigue life and crack retardation behaviour after penetration were examined experimentally using CT specimens and surface pre-cracked specimens of aluminium alloy 5083-0. The fatigue crack shape before penetration is almost semicircular, and the measured aspect ratio is larger than the value obtained by calculation using K values proposed by Newman-Raju. It was found that crack growth behaviour on the back side after penetration is unique, and can be divided into three stages. The Wheeler model retardation parameter was used successfully to predict crack growth behaviour after penetration. By using a crack propagation rule, the change in crack shape after penetration can be evaluated quantitatively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1995.tb00153.x
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  • 4
    Electronic Resource
    Electronic Resource
    Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma (1995)
    Springer
    Journal of neural transmission 101 (1995), S. 237-242 
    Details
    ISSN: 1435-1463
    Keywords: GTP cyclohydrolase I ; tetrahydrobiopterin ; cDNA ; mRNA ; pheochromocytoma ; (Human)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although the existence of three different cDNA forms of human GTP cyclohydrolase I (GCH I) have been reported (Togari et al., 1992), the full-length sequence of any human GCH I cDNA involving poly (A) tail has not yet been documented. In the present study, we first isolated a full-length cDNA clone encoding human GCH I type 1 from human pheochromocytoma cDNA library. The length of the cDNA insert was 2,921 base pairs including poly (A) tail. RNA blot analysis showed a single niRNA species of 4.0kb in human pheochromocytoma tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271561
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  • 5
    Electronic Resource
    Electronic Resource
    Thoracoscopic enucleation of a large leiomyoma located on the left side of the esophageal wall (1997)
    Springer
    Surgical endoscopy and other interventional techniques 11 (1997), S. 280 -282 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Thoracoscopic — Esophageal leiomyoma — Intraoperative esophagoscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thoracoscopic enucleation through the right thorax was successfully performed for a large leiomyoma located on the left wall of the upper-middle esophagus. Using intraoperative esophagoscopy, the exact location of the tumor was identified by trans-illumination. Two sling tapes passed around the esophagus made the procedure as easy as that for tumor located on the right wall of the esophagus. We considered that the thoracoscopic approach through the right thorax can be applied to various types of esophageal leiomyoma, even a large one located on the left side of the esophagus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900344
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  • 6
    Electronic Resource
    Electronic Resource
    Laparoscopic cholecystectomy and time-course changes in renal function (1997)
    Springer
    Surgical endoscopy and other interventional techniques 11 (1997), S. 838 -841 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Laparoscopy — Cholecystectomy — Pneumoperitoneum — Renal function — Retraction method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Recently, the retraction method has been used to reduce intraabdominal pressure (IAP) during laparoscopic surgery. The purpose of this study was to determine the serial changes in renal function during laparoscopic cholecystectomy (LC) using the retraction method. Methods: Urine output, effective renal plasma flow (ERPF), and glomerular filtration rate (GFR) were measured serially in seven patients who underwent LC with 12 mmHg pneumoperitoneum (High-IAP group) and five who underwent LC using the retraction method with 4 mmHg pneumoperitoneum (Low-IAP group). Results: Urine output, ERPF, and GFR were decreased during pneumoperitoneum in the High-IAP group, whereas no significant changes in any of these parameters were observed in the Low-IAP group. Conclusions: Our findings demonstrate that reduction of IAP to 4 mmHg using the retraction method prevents the transient renal dysfunction caused by prolonged 12 mmHg pneumoperitoneum during LC, suggesting that the retraction method reduces the risk of perioperative renal dysfunction during laparoscopic surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900466
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  • 7
    Electronic Resource
    Electronic Resource
    Bereitschaftspotential, Motorpotential und praemotorische Positivierung der menschlichen Hirnrinde vor Willkürbewegungen (1968)
    Springer
    Naturwissenschaften 55 (1968), S. 550-550 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00660147
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  • 8
    Electronic Resource
    Electronic Resource
    Laparoscopic extramucosal myectomy with anterior fundoplication (Dor) for esophageal achalasia using intraoperative manometry (1995)
    Springer
    Surgical endoscopy and other interventional techniques 9 (1995), S. 817-819 
    Details
    ISSN: 1432-2218
    Keywords: Esophageal achalasia ; Laparoscopic surgery ; Extramucosal myectomy ; Dor fundoplication ; Intraoperative manometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Laparoscopic extramucosal myectomy with anterior fundoplication according to the Dor technique was performed on a 24-year-old-woman. Intraoperative inflation of a pneumatic balloon made the operative procedures such as extended submucosal dissection quite easy. Intraoperative gastrofiberscopy was useful for confirming that the remaining mucosal layer was not injured after completion of myectomy. Intraoperative manometry confirmed a complete decompression of the high-pressure zone in the lower esophageal sphincter. Complete relief of the symptoms has been recognized for 6 months after operation without any medication. It is considered that these laparoscopic procedures including intraoperative inflation of a pneumatic balloon, gastrofiberscopy, and intraoperative manometry can be used as a standard operation for esophageal achalasia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190089
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  • 9
    Electronic Resource
    Electronic Resource
    Right atrial to left atrial shunt through foramen ovale during pneumoperitoneum for laparoscopic cholecystectomy (1994)
    Springer
    Surgical endoscopy and other interventional techniques 8 (1994), S. 1110-1112 
    Details
    ISSN: 1432-2218
    Keywords: Right atrial to left atrial shunt ; Foramen ovale ; Pneumoperitoneum ; Laparoscopic cholecystectomy ; Transesophageal Echocardiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 62-year old female patient in whom paradoxical right atrial to left atrial shunt flow through the foramen ovale was detected by transesophageal echocardiography during pneumoperitoneum for laparoscopic cholecystectomy was reported. This patient had a history of mitral valve replacement with residual tricuspid valve regurgitation. It was considered that the onset of paradoxical interatrial shunting through the foramen ovale might be caused not only by mechanical ventilation with positive end-expiratory pressure but also by pneumoperitoneum, especially in patients with heart disease, even if the intra-abdominal pressure was maintained at 12 mmHg.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705732
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  • 10
    Electronic Resource
    Electronic Resource
    Emulsions-polymerisation von Vinylacetat in Gegenwart von Polyvinylalkohol als Emulgator (1974)
    Springer
    Colloid & polymer science 252 (1974), S. 189-189 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01555707
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