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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 16 (1996), S. 33-59 
    ISSN: 1432-0541
    Keywords: Maximum planar subgraph ; Planar subgraph polytope ; Facets ; Branch and cut
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract In automatic graph drawing a given graph has to be laid out in the plane, usually according to a number of topological and aesthetic constraints. Nice drawings for sparse nonplanar graphs can be achieved by determining a maximum planar subgraph and augmenting an embedding of this graph. This approach appears to be of limited value in practice, because the maximum planar subgraph problem is NP-hard. We attack the maximum planar subgraph problem with a branch-and-cut technique which gives us quite good, and in many cases provably optimum, solutions for sparse graphs and very dense graphs. In the theoretical part of the paper, the polytope of all planar subgraphs of a graphG is defined and studied. All subgraphs of a graphG, which are subdivisions ofK 5 orK 3,3, turn out to define facets of this polytope. For cliques contained inG, the Euler inequalities turn out to be facet-defining for the planar subgraph polytope. Moreover, we introduce the subdivision inequalities,V 2k inequalities, and the flower inequalities, all of which are facet-defining for the polytope. Furthermore, the composition of inequalities by 2-sums is investigated. We also present computational experience with a branch-and-cut algorithm for the above problem. Our approach is based on an algorithm which searches for forbidden substructures in a graph that contains a subdivision ofK 5 orK 3,3. These structures give us inequalities which are used as cutting planes. Finally, we try to convince the reader that the computation of maximum planar subgraphs is indeed a practical tool for finding nice embeddings by applying this method to graphs taken from the literature.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 26 (2000), S. 172-195 
    ISSN: 1432-0541
    Keywords: Key words. Minimum capacity cuts, Experimental performance evaluation, Computational comparisons, Literate programming, Algorithm engineering.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. In the late eighties and early nineties, three major exciting new developments (and some ramifications) in the computation of minimum capacity cuts occurred and these developments motivated us to evaluate the old and new methods experimentally. We provide a brief overview of the most important algorithms for the minimum capacity cut problem and compare these methods both with problem instances from the literature and with problem instances originating from the solution of the traveling salesman problem by branch-and-cut.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 13 (1995), S. 357-380 
    ISSN: 1432-0541
    Keywords: Matching ; Heuristics ; Moat packing ; Minimum spanning tree
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract We describe a new heuristic for constructing a minimum-cost perfect matching designed for problems on complete graphs whose cost functions satisfy the triangle inequality (e.g., Euclidean problems). The running time for ann node problem is O(n logn) after a minimum-cost spanning tree is constructed. We also describe a procedure which, added to Kruskal's algorithm, produces a lower bound on the size of any perfect matching. This bound is based on a dual problem which has the following geometric interpretation for Euclidean problems: Pack nonoverlapping disks centered at the nodes and moats surrounding odd sets of nodes so as to maximize the sum of the disk radii and moat widths.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 16 (2002), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An early clinical symptom in scleroderma patients is Raynaud's phenomenon. Later cutaneous manifestations of the disease include oedematous swelling in the extremities and in more extreme cases often very painful, refractory acral necroses. We report on a 56-year-old female patient who participated in a prospective, double-blind, multicentre comparative pilot study because of her severe Raynaud symptoms, with dystrophic skin lesions on both hands. The goal of the study was to evaluate the efficacy and safety of prostaglandin E1 ethyl ester in a transdermal drug delivery system compared with placebo in patients with secondary Raynaud's phenomenon associated with systemic scleroderma or mixed connective tissue disease. After 2 weeks of verum treatment the patient experienced a marked improvement of Raynaud's attacks, with increased capillary flow velocity, reduced blood stasis and clinical healing of the acral trophic lesions. For this patient the transdermal application of prostaglandin E1 ethyl ester in the form of a medicated patch proved to be a simple and effective therapy for the acral trophic skin lesions associated with systemic scleroderma.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 15 (2001), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 137 (1997), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Synchronous measurement of laser Doppler flux (LDF) and capillary red blood cell velocity (CBV) was performed in adjacent areas of the same nailfold during a local cold stress test in 12 healthy controls (eight women and four men) and in 22 patients (17 women and seven men) with secondary Raynaud's phenomenon before and after treatment. Two questions were addressed: Are there any differences in the signal pattern between LDF and RBV? Is it possible to detect early on in therapy, before clinical benefit becomes obvious, whether a treatment is successful or not?Despite the fact that the resulting signal patterns recorded by these two techniques are widely compatible, certain differences could be observed. In healthy controls, decrease of values during cooling time and increase after cooling were more distinct in RBV than in LDF.Compared with control values, CBV and LDF in patients with Raynaud's phenomenon were lower. After cooling CBV took an average of 3 min to reach initial value again as compared with 40s in healthy controls. During 4 min observation time, pretest values of LDF were not achieved again in patients, whereas it took 50s in healthy controls.If, after a few days of vasospasmolytic therapy, test results improved or normalized, clinical symptoms subsided gradually during the next weeks. Clinical improvement was not observed in those patients in whom cutaneous blood flow remained decreased despite therapy. CBV indicated this more clearly than LDF. Duration of flow stop at the end of cooling showed a marked improvement in patients treated successfully.Discrepancies between CBV and LDF are interpreted as being due to LDF detecting other vessels in addition to the superficial, nutritional capillaries. LDF seemed to be a poor tool for evaluating the effect of treatment. Determination of CBV and flow stop duration during local cold exposure may help in early selection of the best treatment for a patient with Raynaud's phenomenon by predicting later possible clinical benefit.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 144 (2001), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical programming 44 (1989), S. 127-137 
    ISSN: 1436-4646
    Keywords: Cutting plane algorithm ; polytopes ; facets ; quadratic 0–1 programming
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract We present computational experience with a cutting plane algorithm for 0–1 quadratic programming without constraints. Our approach is based on a reduction of this problem to a max-cut problem in a graph and on a partial linear description of the cut polytope.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Computing 47 (1991), S. 43-49 
    ISSN: 1436-5057
    Keywords: 51-04 ; 68Q25 ; 68R10 ; Computational geometry ; Voronoi diagram ; Delaunay triangulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung In den letzten Jahren hat die praktische Berechnung von Delaunay-Triangulationen bzw. Voronoi-Diagrammen große Aufmerksamkeit erfahren, da sie wichtige grundlegende Konzepte für geometrische Algorithmen darstellen. In dieser technischen Notiz betrachten wir das Problem ihrer numerisch stabilen Berechnung. Hierzu nehmen wir an, daß die generierenden Punkte Gitterpunkte eines quadratischenM×M-Gitters in der Ebene sind. Abhängig vonM bestimmen wir die notwendige Wortlänge zur Durchführung ganzzahliger Arithmetik, die es erlaubt, Delaunay-Triangulationen exakt zu berechnen. Die Analyse wird für dieL 1-,L 2- undL ∞-Metrik durchgeführt.
    Notes: Abstract In recent years the practical computation of Delaunay triangulations, resp. Voronoi diagrams has received a lot of attention in the literature. While the Delaunay triangulation is an important basic tool in geometric optimization algorithms, it is nontrivial to achieve a numerically stable computer implementation. In this technical note we assume that all generating points are grid points of a regularM byM lattice in the plane. Depending onM we derive the necessary word length a binary computer must have for integer representation in order to obtain exact Delaunay triangulations. This analysis is carried out for theL 1-,L 2- andL ∞-metric.
    Type of Medium: Electronic Resource
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