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  • 1
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Nekrolytisches migratorisches Erythem ; Paraneoplasie ; Plattenepithelkarzinom ; Glukagonom ; Key words Necrolytic migratory erythema ; Paraneoplasia ; Squamous cell carcinoma ; Glucagonoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A 59-year-old Caucasian man suffered from persistent disseminated necrolytic skin lesions for 8 months. They failed to respond to a variety of therapeutic regimens but then cleared spontaneously within a few days. After one week an invasive squamous cell carcinoma of the hypopharynx became clinically apparent. At autopsy, the expected glucagonoma often associated with necrolytic migratory erythema was not found.
    Notes: Zusammenfassung Nach achtmonatiger therapierefraktärer Persistenz disseminierter nekrolytischer Hautveränderungen kam es bei einem 59jährigen Patienten zu einer spontanen Abheilung der Läsionen innerhalb weniger Tage. Eine Woche später manifestierte sich klinisch ein invasiv wachsendes Plattenepithelkarzinom des Hypopharynx. Ein im Rahmen der kutanen Paraneoplasie zu erwartendes Glukagonom konnte autoptisch nicht nachgewiesen werden.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 48 (1997), S. 492-495 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Embolia cutis medicamentosa ; Hautnekrose ; Intramuskuläre Injektion ; Key words Embolia cutis medicamentosa ; Skin necrosis ; Intramuscular injection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A 35 year-old male suffered from an extremely painful embolia cutis medicamentosa. The atypical segmental localization first led to the diagnosis of herpes zoster and an antiviral therapy. Regarding the unusual course of the complication following an intramuscular injection in this case, the question for the real pathomechanisms still remains.
    Notes: Zusammenfassung Wir berichten über den Fall eines 35jährigen Bürokaufmannes, der an einer ausgesprochen schmerzhaften Embolia cutis medicamentosa litt. Als Besonderheit ist die untypische segmentale Lokalisation im Versorgungsgebiet L1 zu werten, die zunächst zu der klinischen Diagnose eines nekrotisierenden Zosters und einer konservativen antiviralen Therapie führte sowie der ungewöhnliche Verlauf der subjektiven Beschwerden und das Intervall bis zum Auftreten der charakteristischen Hauterscheinungen, wodurch sich erneut die Frage nach den zugrundeliegenden pathogenetischen Vorgängen stellt.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Protoplasma 64 (1967), S. 209-212 
    ISSN: 1615-6102
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary These studies demonstrate that there is an increase in the incorporation rate of both protein and RNA precursors intoFucus eggs at the time of fertilization. In biochemical terms, therefore, fertilization means activation of the egg immediately after penetration of the sperm. The problem arises: is this ade novo transcription of the information stored in the nucleus as the consequence of derepression of certain genes or are the polysomal particles already present before germination begins (Linskens 1967). Then fertilization would mean an activation of preformed structures ready for activity, but depressed until the sperm brings the initiating signal. Only speculation can be made about biochemical mechanisms involved here; but the system seems to be useful for further investigations.
    Type of Medium: Electronic Resource
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