ISSN:
1662-0356
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Natural Sciences in General
,
Technology
Notes:
Potential application of Carbon Nanotubes as a drug delivery system is limited by theirhydrophobity and their natural tendency to aggregate in the bundles. Dispersion and solubility ofSinglewall Carbon Nanotubes (SWCNT) in Phosphate Buffered Saline (PBS) solution via noncovalent and covalent interactions was investigated. Galactosyl-β1-Sphyngosine (glycolipidprecursor of cerebrosides, structured with a hydrophobic chain, a hydrophilic head and an aminegroup between them) was used.Pristine SWCNTs were wrapped with Galactosyl-β1-Sphyngosine (Gal-Sphy), whereas thecarboxylic groups of the functionalized CNTs were activated in order to interact with amine groupsof Galactosylsphyngosine and render the coating stronger.Samples dispersion was characterized by optical absorption spectroscopy (OAS). The comparisonand efficiency of the dispersion stability of the functionalized material in respect to the pristineSWCNTs will be presented. We exploited Raman Spectroscopy to evaluate relative purity of thesamples, and the Infrared analysis to characterize the presence of the functional groups on the tubessurface. The morphology of the samples was studied using high resolution transmission electronmicroscopy (HR-TEM)
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/42/transtech_doi~10.4028%252Fwww.scientific.net%252FAST.57.44.pdf
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