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  • 1
    Electronic Resource
    Electronic Resource
    Dietary treatment for decreasing 141Ce body burden in immature rats (1987)
    Springer
    Archives of toxicology 59 (1987), S. 371-373 
    Details
    ISSN: 1432-0738
    Keywords: 141Ce ; Diet ; Reduced absorption ; Immature rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of this work was to evaluate the effect of prolonged (immediate or delayed) administration of dietary additives to suckling rats on the absorption and retention of radioactive cerium in the body. The experiment was performed on 6-day-old suckling rats. According to dietary treatment the animals were divided into thee groups. Each group was artificially fed over 8 h for 6 or 12 days on one of the diets: the first group of animals was fed milk, the second group was given ingredients of rat diet and the third received milk during the first 2 days of the experiment and the ingredients of rat diet afterwards. At the end of the artificial feeding period the pups returned to their mothers and suckled overnight. On the 1st day of the experiment the food was labelled with 141Ce. Whole body radioactivity was determined in a double crystal scintillation counter every 48 h over a 12-day period. Half of the animals from each group were killed 6 days after 141Ce administration and the other half after 12 days. At these intervals retention was determined in the gut, liver, idneys and femur. The early and delayed administration of rat diet ingredients — fish meal, sunflower meal, alfalfa, cane molasses and premix — greatly reduced whole body retention. The early treatment was more efficacious than the delayed one. The reduction was mostly due to decreased gut retention but organ retentions were also lower. The results obtained indicate that by prolonged (immediate or delayed) administration of some dietary means the retention of radioactive cerium in sucklings can be significantly decreased.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00295092
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of 2,3-dimercaptopropane sodium sulfonate on mercury retention in rats in relation to age (1984)
    Springer
    Archives of toxicology 55 (1984), S. 250-252 
    Details
    ISSN: 1432-0738
    Keywords: 203Hg ; DMPS ; Age ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effectiveness of DMPS (sodium 2,3-dimercaptopropane-1-sulfonate) in reducing inorganic mercury retention was studied in 2-, 6-, and 28-week-old albino rats. 203Hg was administered IP. The chelating agent DMPS was administered by IP injection at a dose of 250 μmol/kg body weight three times, 1 day after 203Hg administration and at 24 h intervals thereafter. The whole body retention determined 1, 2, 3, and 6 days after 203Hg administration showed that DMPS decreased the body retention of mercury in all age groups, being about twice as effective in adult compared to suckling rats. The reduced effectiveness was due to the reduced efficacy of DMPS in reducing kidney retention in young animals. In other organs the effectiveness of DMPS was not age dependent. These and previous results obtained with different chelating agents and other metals indicate that age might be an important factor in chelation therapy in general.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341020
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of glucocorticoids on metal retention in rats (1990)
    Springer
    Bulletin of environmental contamination and toxicology 45 (1990), S. 655-661 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01700982
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    2,3-Dimercaptopropane-1-sodium sultanate for reducing retention of ingested203Hg in suckling rats (1988)
    Springer
    Bulletin of environmental contamination and toxicology 41 (1988), S. 185-188 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01705428
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of cadmium-mobilizing dithiocarbamates on essential trace metal metabolism in rats (1991)
    Springer
    Bulletin of environmental contamination and toxicology 47 (1991), S. 160-164 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01689468
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    Paper (German National Licenses)
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