ISSN:
0947-3440
Keywords:
Natural products
;
Biomimetic synthesis
;
Palmarumycins
;
Phenol oxidation
;
CD quantumchemical calculations
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The first “open chain” representative of the palmarumycins, the biaryl ether 1, was isolated from Coniothyrium palmarum. Phenol oxidation of 1 with silver oxide as a model for a biosynthetic step yielded 4 with the usual spiroacetal structure of the palmarumycins. The absolute (S)-configuration of 4 (and thus of 1) was determined by quantumchemical CD calculations.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199719971216
Permalink