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  • 1
    Electronic Resource
    Electronic Resource
    Detection of Diterpenoid Alkaloids in Aphids Feeding on Aconitum napellus and Aconitum paniculatum (1990)
    s.l. : American Chemical Society
    Journal of natural products 53 (1990), S. 204-206 
    Details
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/np50067a033
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  • 2
    Electronic Resource
    Electronic Resource
    Distribution of mercury in the sediments of New Haven (Conn.) Harbor (1972)
    s.l. : American Chemical Society
    Environmental science & technology 6 (1972), S. 1123-1124 
    Details
    ISSN: 1520-5851
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/es60072a007
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  • 3
    Electronic Resource
    Electronic Resource
    Role of Hydrogen in Semiconductor, Dielectric and Metal Deposition onto InP by Means of Rapid Thermal Low Pressure Metalorganic Chemical Vapor Deposition (1993)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 148-149 (Dec. 1993), p. 61-112 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/00/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.148-149.61.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Insulin mediators in man: effects of glucose ingestion and insulin resistance (1997)
    Springer
    Diabetologia 40 (1997), S. 557-563 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Inositol phosphoglycans ; non-insulin dependent diabetes mellitus ; pyruvate dehydrogenase ; cyclic AMP dependent protein kinase.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Insulin mediators (inositol phosphoglycans) have been shown to mimic insulin action in vitro and in intact mammals, but it is not known which mediator is involved in insulin action under physiological conditions, nor is it known whether insulin resistance alters the mediator profile under such conditions. We therefore investigated the effects of glucose ingestion on changes in the bioactivity of serum inositol phosphoglycan-like substances (IPG) in healthy men and insulin resistant (obese, non-insulin-dependent diabetic) men. Two classes of mediators were partially purified from serum before and after glucose ingestion. The first was eluted from an anion exchange resin with HCl pH 2.0, and bioactivity was determined by activation of pyruvate dehydrogenase in vitro. The second was eluted with HCl pH 1.3, and bioactivity was determined by inhibition of cyclic AMP-dependent protein kinase. In healthy men, the bioactivity of the pH 1.3 IPG was not altered by glucose ingestion, whereas bioactivity of the pH 2.0 IPG increased to approximately 120 % of the pre-glucose ingestion value at 60–240 min post-glucose ingestion (p 〈 0.05 vs pre-glucose). There was no change in either IPG after glucose ingestion in the insulin-resistant group. These data suggest that the pH 2.0 IPG plays an important role in mediating insulin's effect on peripheral glucose utilization in man under physiological conditions. The data further show, for the first time, a defective change in the bioactivity of an insulin mediator isolated from insulin-resistant humans after hyperinsulinaemia, suggesting that inadequate generation/release of IPGs is associated with insulin resistance. [Diabetologia (1997) 40: 557–563]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050715
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  • 5
    Electronic Resource
    Electronic Resource
    Role of the kidney in hormone metabolism and its implications in clinical medicine (1980)
    Springer
    Journal of molecular medicine 58 (1980), S. 1005-1012 
    Details
    ISSN: 1432-1440
    Keywords: Niere ; Hormone ; urämische Endocrinopathien ; Kidney-Hormones ; Uremic endocrinopathies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Uremia is accompanied by a variety of metabolic and endocrine disorders, due in part to impaired degradation of hormonally active peptides by the diseased kidney, and in part to the fact that the uremic environment interferes with the extrarenal degradation of certain hormones, or with their synthesis or secretion. It is not always possible to establish a direct cause and effect relationship between alterations in immunoassayable hormone levels and endocrine abnormalities because in uremia the circulating hormonal immunoreactivity frequently includes crossreacting components without biological activity and, in addition, hormonal effects on target organs are often altered. Alterations in the metabolism of pancreatic alpha and beta cell hormones and of prolactin in chronic renal failure and their effect on the metabolism of lipids and carbohydrates and on reproductive function in this condition are discussed.
    Notes: Zusammenfassung Die Urämie wird von verschiedenen metabolischen und endokrinen Störungen begleitet, die einerseits die Degradation hormonal aktiver Peptide in der erkrankten Niere behindern, andererseits durch direkte Auswirkungen des urämischen Milieus auf die extrarenale Degradation verschiedener Hormone, ihre Synthese oder Sekretion hervorgerufen sind. Es gelingt nicht immer, eine direkte Ursachen-Wirkung-Beziehung zwischen Änderungen des immunreaktiven Hormonspiegels und endokriner Funktionsstörung herzustellen, da in der Uramie die zirkulierende hormonale Immunreaktivität häufig kreuzreagierende Komponenten ohne biologische Aktivität einschließt und zusätzlich die Wirkung verschiedener Hormone auf ihre Zielorgane verändert ist. Abweichungen im Stoffwechsel der pankreatischen α- und β-Zellhormone und von Prolactin bei chronischem Nierenversagen sowie ihr Effekt auf den Stoffwechsel von Lipiden und Kohlenhydraten und auf die reproduktive Funktion werden in diesem Zusammenhang diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01476870
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  • 6
    Electronic Resource
    Electronic Resource
    Chemical and biological studies on the lipopolysaccharide (O-antigen) of Anacystis nidulans (1977)
    Springer
    Archives of microbiology 113 (1977), S. 247-256 
    Details
    ISSN: 1432-072X
    Keywords: Lipopolysaccharide ; O-antigen ; 3- and 4-O-Methyl-D-mannose ; Degraded polysaccharide ; Toxicity ; Anticomplementary activity ; Anacystis nidulans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The O-antigen (lipopolysaccharide) of Anacystis nidulans, strain KM, has been isolated from whole cells and from cell wall preparations by phenolwater extraction. The polysaccharide moiety consists of a D-mannose polymer accompanied by smaller amounts of 3- and 4-O-methyl-D-mannoses, D-galactose, D-glucose, L-fucose, D-glucosamine, mannosamine and 2-keto-3-deoxyoctonate. Aldoheptoses are lacking. The degraded polysaccharide is split from lipid A by acid hydrolysis (10% acetic acid, 100°C, 3 h) whereby 2-keto-3-deoxyoctonate is released in small amounts. Degraded polysaccharide forms only one major fraction by Sephadex G-50 gel-filtration. This fraction includes all the sugars mentioned above except L-fucose, which is released during the acetic acid degradation. Periodate studies and methylation analysis revealed that the poly-mannose chain consists of about 75% 1→3 linked and of 25% 1→4 linked D-mannose units. Lipid A of A. nidulans is phosphate-free. The main fatty acid, β-hydroxypalmitic acid, is exclusively amide-bound, presumably to the amino group of D-glucosamine. Other fatty acids, found as minor constituents, are β-hydroxymyristic, palmitic and stearic acids. Lipopolysaccharide of A. nidulans KM exhibits high anticomplementary activity in guineapig serum. It is about 800 times less toxic for adrenalectomized mice than endotoxin from Salmonella typhimurium. The isolated lipopolysaccharide reacts with rabbit antisera against living or heat-killed cells of A. nidulans in passive hemagglutination, when untreated or heated, but not when alkali-treated lipopolysaccharide is used for red blood cell sensibilization. It is concluded that lipopolysaccharide of A. nidulans KM is exposed on the surface of the cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00492032
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  • 7
    Electronic Resource
    Electronic Resource
    High Temperature Defect-Free Rapid Thermal Annealing of III-V Substrates in Metallorganic Controlled Ambient (1992)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 83-87 (Jan. 1992), p. 1509-1518 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/21/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.83-87.1509.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    Anomalous Damage Depths in Low-Energy Ion Beam Processed III-V Semiconductors (1992)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 83-87 (Jan. 1992), p. 1439-1444 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/21/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.83-87.1439.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Crystallization and preliminary X-ray diffraction studies of E. coli porphobilinogen synthase and its heavy-atom derivatives (1998)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 438-440 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Porphobilinogen synthase (PBGS) catalyzes the condensation of two identical substrate molecules, 5-aminolevulinic acid (ALA), in an asymmetric manner to form porphobilinogen. E. coli PBGS is an homooctameric enzyme. The number of active sites is not clear, but each subunit binds one ZnII ion and one MgII ion. Diffraction-quality crystals of native E. coli PBGS have been obtained, and unit-cell dimensions (a = 130.8, c = 144.0 Å) are reported. These crystals diffract to about 3.0 Å resolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444997010925
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  • 10
    Electronic Resource
    Electronic Resource
    Interpretation of Spring Recession Curves (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 40 (2002), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Recession curves contain information on storage properties and different types of media such as porous, fractured, cracked lithologies and karst. Recession curve analysis provides a function that quantitatively describes the temporal discharge decay and expresses the drained volume between specific time limits (Hall 1968). This analysis also allows estimating the hydrological significance of the discharge function parameters and the hydrological properties of the aquifer. In this study, we analyze data from perennial springs in the Judean Mountains and from others in the Galilee Mountains, northern Israel. All the springs drain perched carbonate aquifers. Eight of the studied springs discharge from a karst dolomite sequence, whereas one flows out from a fractured, slumped block of chalk. We show that all the recession curves can be well fitted by a function that consists of two exponential terms with exponential coefficients α1 and α2. These coefficients are approximately constant for each spring, reflecting the hydraulic conductivity of different media through which the ground water flows to the spring. The highest coefficient represents the fast flow, probably through cracks, or quickflow, whereas the lower one reflects the slow flow through the porous medium, or baseflow. The comparison of recession curves from different springs and different years leads to the conclusion that the main factors that affect the recession curve exponential coefficients are the aquifer lithology and the geometry of the water conduits therein. In normal years of rainy winter and dry summer, α1 is constant in time. However, when the dry period is longer than usual because of a dry winter, α1 slightly decreases with time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.2002.tb02539.x
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