ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The purpose of this study was to examine if the application of titanium-reinforced expandedpolytetrafluoroethylene(TR-ePTFE) membrane combined with bovine bone mineral(BBM) soakedin inorganic polyphosphate promotes exophytic bone formation in rabbit calvaria. For this purpose,a total of 8 rabbits were used, and rectangular decorticated calvaria sites were created using a roundcarbide bur. In the control group, rectangular parallelepiped-shaped TR-ePTFE membranes(RPTPMs) were filled with BBM soaked in saline and placed on the decorticated sites and fixedwith metal pins. In the experimental groups, RPTPMs were filled with BBM soaked in 4%, 8% and16% inorganic polyphosphate prior to fixing with metal pins. Animals were sacrificed at 4 and 8weeks after surgery, and new bone formation was assessed by histomorphometric as well asstatistical analysis. The results indicated that at 8 weeks, all the experimental groups demonstratedexophytic bone formation. At 8 weeks, the 8% polyphosphate group revealed the most new boneformation (p〈0.05). On the basis of these findings, we conclude that inorganic polyphosphate has apromoting effect on bone regeneration, possibly by enhancing osteoinductivity of the decorticatedwound area and osteoconductivity of the carrier material, but not much as we expected
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.1075.pdf
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