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Microcephaly with peculiar demyelination mimicking Pelizaeus-Merzbacher disease (1977)

Kamoshita, S. ; Igarashi, M. ; Kohno, R.

Springer

Acta neuropathologica 40 (1977), S. 95-98

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ISSN: 1432-0533

Keywords: Microcephaly ; Pelizaeus-Merzbacher disease ; Patchy demyelination ; Anoxic leukoencephalopathy

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The neuropathological studies of a 4-year old idiot with microcephaly revealed a striking demyelinating disease compatible with Pelizaeus-Merzbacher disease. The case seemed to be best classified as the patchy demyelination type, but the most unusual finding was a prominent vasculature in some demyelinated areas. Intrauterine hypoxia was proposed as a causative factor of this type of demyelinative lesions

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00688579

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