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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of mathematical biology 38 (1999), S. 241-261 
    ISSN: 1432-1416
    Keywords: Key words: Cell division ; Stability ; Gamma distribution ; Measure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract.  This paper couples a general d-dimensional (d arbitrary) model for the intracellular biochemistry of a generic cell with a probabilistic division hypothesis and examines the consequence of division for stability of cell function and structure. We show rather surprisingly that cell division is capable of giving rise to a stable population of cells with respect to function and structure even if, in the absence of cell division, the underlying biochemical dynamics are unstable. In the context of a simple example, our stability condition suggests that rapid cell proliferation plays a stabilizing role for cellular populations.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of mathematical biology 30 (1992), S. 775-800 
    ISSN: 1432-1416
    Keywords: Statistical dynamics ; Asymptotic periodicity ; Asymptotic stability ; Cell cycle models ; Neuron interspike interval statistics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract In this paper we develop a general modeling framework within which many models for systems which produce events at irregular times through a combination of probabilistic and deterministic dynamics can be comprehended. We state and prove new sufficient conditions for the global asymptotic behaviour of the density evolution in these systems, and apply our results to many previously published models for the cell division cycle. In addition, we develop a new interpretation for the statistics of action potential production in excitable cells.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of statistical physics 60 (1990), S. 735-751 
    ISSN: 1572-9613
    Keywords: Stochastic differential equations ; Fokker-Planck equation ; Hopf bifurcation ; Liapunov functions ; global stability ; noise-induced transitions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We prove analytically that additive and parametric (multiplicative) Gaussian distributed white noise, interpreted in either the Itô or Stratonovich formalism, induces global asymptotic stability in two prototypical dynamical systems designated as supercritical (the Landau equation) and subcritical, respectively. In both systems without noise, variation of a parameter leads to a switching between a single, globally stable steady state and multiple, locally stable steady states. With additive noise this switching is mirrored in the behavior of the extrema of probability densities at the same value of the parameter. However, parametric noise causes a noise-amplitude-dependent shift (postponement) in the parameter value at which the switching occurs. It is shown analytically that the density converges to a Dirac delta function when the solution of the Fokker-Planck equation is no longer normalizable.
    Type of Medium: Electronic Resource
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  • 4
    Title: Chaos, fractals, and noise : stochastic aspects of dynamics; 97
    Author: Lasota, Andrzej
    Contributer: Mackey, Michael C.
    Edition: 2nd ed.
    Publisher: Berlin u.a. :Springer,
    Year of publication: 1994
    Pages: 472 S.
    Series Statement: Applied mathematical sciences 97
    Type of Medium: Book
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