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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 24 (1959), S. 115-116 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 75 (1953), S. 1254-1254 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0460
    Keywords: Human saliva, lubrication ; Artificial saliva, lubrication ; Saliva, viscosity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The lubrication regime displayed by human salivas (parotid and submandibular-sublingual), purified salivary molecules (the mucins MG1 and MG2 and α-amylases), and selected artificial salivas (Oracare D, Saliva Substitute, and Orthana) was assessed in vitro using a friction-testing device. Thin-film (boundary) lubrication was observed for all of the salivary samples and two of the artificial salivas examined. Oracare D, a glycerol-based artificial saliva, was the exception since it lubricated by a thick-film (hydrodynamic) regime. On a molar basis, the best lubricants of the purified salivary molecules were MG1 〉 MG2 ≈ nonglycosylated α-amylases ≈ glycosylated α-amylases.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 19 (1994), S. 6-7 
    ISSN: 1432-0509
    Keywords: Esophagus, stricture ; Esophagitis, drug-induced
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 37-year-old man experienced acute odynophagia after ingesting a single tablet of Motrin (ibuprofen, 800 mg). Because the pill was swallowed without water, a transient delay in its passage through the esophagus resulted in localized mucosal inflammation and a druginduced stricture.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 19 (1994), S. 295-297 
    ISSN: 1432-0509
    Keywords: Stomach ; inflammation ; Antral deformity ; drug-induced ; Gastropathy ; NSAID complication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have occasionally encountered patients on nonsteroidal antiinflammatory drugs (NSAIDs) in whom double contrast barium studies revealed persistent flattening and stiffening of the distal greater curvature of the stomach. We therefore performed a study to determine the frequency of this finding in patients with NSAID-related gastropathy. Twenty-one cases of erosive gastritis, gastric ulcers, and/or gastric scarring associated with a known history of NSAID use were reviewed by two radiologists who made a joint decision regarding the presence or absence of greater curvature antral flattening. This finding was seen radiographically in five of the 21 patients (24%). Four of the five patients with antral flattening had associated erosions or ulcers in the gastric antrum. The remaining patient had antral flattening as an isolated finding. Our experience suggests that flattening of the greater curvature of the distal antrum, particularly if associated with erosive gastritis or gastric ulcers, is a useful radiologic sign of NSAID-related gastropathy.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 22 (1997), S. 5 -7 
    ISSN: 1432-0509
    Keywords: Key words: Reflux esophagitis—Gastroesophageal reflux disease—Esophageal ulcers. [xm [fs99]
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: Some patients with reflux esophagitis have solitary ulcers in the distal esophagus. This study was undertaken to characterize further the radiographic features of these ulcers and to determine whether or not they have a predisposition to develop on the posterior esophageal wall. Methods: Radiologic files and teaching files at our university hospital and affiliated Veterans Administration hospital revealed 29 patients with solitary reflux-induced ulcers. The radiographs were reviewed retrospectively to determine the size and location of the ulcers as well as the presence or absence of other findings. Results: Twenty ulcers (69%) were located on the posterior wall, five (17%) on the left or right lateral wall, and four (14%) on the anterior wall. All but two ulcers were located 1–4 cm from the gastroesophageal junction. All of the ulcers were less than 10 mm in width and 5 mm in depth. Other associated findings included hiatal hernias in 11 patients (38%), mucosal nodularity or granularity in 12 (41%), one or more tiny satellite ulcers in three (10%), esophageal intramural pseudodiverticula in three (10%), an inflammatory esophagogastric polyp in one (3%), and scarring or stricture formation in 12 (41%). Conclusion: Our findings suggest that solitary reflux-induced ulcers tend to occur on the posterior wall of the distal esophagus near the gastroesophageal junction, producing characteristic radiographic findings. We postulate that affected individuals sleep primarily in the supine position, so that refluxed acid pools on the dependent or posterior esophageal wall, causing maximal injury in this location.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0509
    Keywords: Key words: Proctocolectomy—Ileoanal pouch.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To assess the role of contrast enemas for the evaluation of leaks in symptomatic and asymptomatic patients after the first stage of restorative proctocolectomy. Methods: We reviewed the findings of 59 contrast enemas in 40 patients who underwent total proctocolectomy with creation of an ileoanal pouch and a proximal diverting ileostomy. Thirty-seven patients initially underwent routine contrast studies of the ileoanal pouch, and three underwent contrast studies because of suspected fistulas or obstruction. Medical records were also reviewed to determine the clinical presentation and course of these patients. Results: Of 37 patients who underwent routine postoperative contrast enemas, 33 (89%) had normal studies, three (8%) had clinically silent leaks (including two blind-ending tracks from the ileoanal anastomosis and one from the pouch), and one (3%) had pouchitis. In all three patients with unsuspected leaks, ileostomy closure was delayed. In two other patients with abdominal pain and fever, contrast enemas revealed leaks from the ileoanal pouch and distal ileum, respectively. The remaining patient had a contrast enema because of abdominal pain and distention; this patient had a distal ileal obstruction due to adhesions. Conclusions: Routine postoperative contrast studies revealed clinically silent leaks from the ileal J pouch or ileoanal anastomosis in three of 37 patients (8%) after the first stage of restorative proctocolectomy. Our findings suggest that routine contrast enema can detect clinically silent leaks after this surgery.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0509
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 20 (1995), S. 291-298 
    ISSN: 1432-0509
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion Barrett's esophagus is probably a more common condition than previously recognized. Although the classic radiologic findings of Barrett's esophagus are present in only a small percentage of patients, this condition should be suspected whenever reflux esophagitis or peptic strictures are demonstrated on double-contrast esophagography. Recent literature also suggests that Barrett's carcinomas comprise up to 50% of all esophageal cancers. Because of the increased risk of developing adenocarcinoma in Barrett's esophagus, endoscopic surveillance has been advocated to detect dysplastic or carcinomatous changes at the earliest possible stage. When barium studies are performed on patients with known Barrett's esophagus, the radiographs should be carefully evaluated for signs of early adenocarcinoma, so these patients can be referred for appropriate management prior to the development of advanced, unresectable tumors.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0509
    Keywords: Key words: Gastrointestinal lymphoma—Non-Hodgkin's gastrointestinal lymphoma—Barium studies.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: To determine the predictive value of a single lesion versus multifocal disease for differentiating primary and secondary gastrointestinal (GI) lymphoma on barium studies. Methods: Our study group consisted of 90 cases of non-Hodgkin's GI lymphoma from the radiologic archives of the Armed Forces Institute of Pathology in which barium studies had been performed. Each of those studies was reviewed jointly by two of the authors to determine in a blinded fashion whether the patients had a single lesion or multifocal disease (defined as two or more discrete lesions). Medical and pathologic records were then reviewed to determine whether these patients had primary (defined as lymphoma arising in the GI tract) or secondary (defined as disseminated lymphoma with associated GI tract involvement) GI lymphoma. The final clinical diagnosis was then correlated with the radiographic findings to test the hypothesis that a single lesion is more likely to be associated with primary GI lymphoma and that multifocal disease is more likely to be associated with secondary GI lymphoma. Results: Sixty-eight patients had a single lesion in the GI tract on barium studies; 52 (76%) of these patients had primary GI lymphoma and 16 (24%) had secondary GI lymphoma. Another 22 patients had multifocal disease on barium studies; 20 (91%) of these patients had secondary GI lymphoma and two (9%) had primary GI lymphoma. Conclusion: The predictive value of a single lesion for primary GI lymphoma on barium studies was 76%, and the predictive value of multifocal disease for secondary GI lymphoma was 91%. Thus, our data suggest that it is often possible to differentiate these two forms of GI lymphoma on the basis of the radiographic findings.
    Type of Medium: Electronic Resource
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