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  • 1
    Electronic Resource
    Electronic Resource
    Electron transfer. 35. Some reactions of carboxylatopentaamminechromium(III) complexes with one-electron reductants (1978)
    s.l. : American Chemical Society
    Inorganic chemistry 17 (1978), S. 1831-1834 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50185a027
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  • 2
    Electronic Resource
    Electronic Resource
    Protein partitioning in two-phase aqueous nonionic micellar solutions (1992)
    s.l. : American Chemical Society
    Macromolecules 25 (1992), S. 4797-4806 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00044a048
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  • 3
    Electronic Resource
    Electronic Resource
    Prostaglandin E2 suppresses phytohemagglutin-induced immune responses of normal human monoculear cells by decreasing intracellular glutathione generation, but not due to increased DNA strand breaks or apoptosis (1993)
    Springer
    Inflammation research 40 (1993), S. 191-199 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Prostaglandin E2 (PGE2) at concentrations more than 1×10−8 M markedly suppressed the cell proliferation and release of soluble molecules of interleukin-2 receptor (sIL-2R), CD4 (sCD4) and CD8 (sCD8) from phytohemagglutinin (PHA)-stimulated normal human mononuclear cells (MNC) in a dose-related manner. To further elucidate the subcellular mechanism of the inhibitory effect of PGE2 on PHA-stimulated MNC, intracellular concentration of glutathione (GSH) in PHA-stimulated MNC was sequentially measured from day 1 to day 3 by enzymic method. Furthermore, the effect of PGE2 on nuclear DNA including DNA strand breaks in alkali treatment and DNA fragmentation (apoptosis) of PHA-stimulated MNC were also measured. We found intracellular GSH levels were significantly decreased in the early stage of lymphocyte activation (day 1), but no evidence of increased DNA stand breaks or apoptotic process appeared in 3-day culture. In addition, butathione sulfoximine (a specific GSH inhibitor) and dibutyryl cyclic AMP also exhibited both proliferation inhibition and GSH-decreasing effect on PHA-stimulated MNC as well as PGE2. These results suggest that the immunosupressive effect of PGE2 is mediated by the decreased generation of intracellular GSH, but not by the increased DNA strand breaks or apoptotic mechanism in the cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01984061
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  • 4
    Electronic Resource
    Electronic Resource
    Optimal Graph Constraint Reduction for Symbolic Layout Compaction (1997)
    Springer
    Algorithmica 18 (1997), S. 560-574 
    Details
    ISSN: 1432-0541
    Keywords: Key words. VLSI layout, Compaction, Graph constraints, Constraint graphs, Constraint reduction, Transitive reduction, Difference constraints.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. The compaction problem in VLSI layout can be formulated as a linear program. To reduce the execution time and memory usage in compaction, it is important to reduce the size of the linear program. Since most constraints in compaction are derived directly or indirectly from physical separation and electrical connectivity requirements which can be expressed in the form of graph constraints, we study the graph constraint reduction problem. That is the problem of producing, for a given system of graph constraints, an equivalent system with the fewest graph constraints. After observing that the problem as previously formulated is NP-hard and overrestrictive in that the maximum possible reduction is not always attainable, we propose a new formulation in which the maximum possible reduction is guaranteed. We further present a polynomial-time algorithm for the new formulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00009173
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  • 5
    Electronic Resource
    Electronic Resource
    Floorplan design of VLSI circuits (1989)
    Springer
    Algorithmica 4 (1989), S. 263-291 
    Details
    ISSN: 1432-0541
    Keywords: VLSI circuit layout ; Floorplan design ; Simulated annealing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract In this paper we present two algorithms for the floorplan design problem. The algorithms are quite similar in spirit. They both use Polish expressions to represent floorplans and employ the search method of simulated annealing. The first algorithm is for the case where all modules are rectangular, and the second one is for the case where the modules are either rectangular or L-shaped. Our algorithms consider simultaneously the interconnection information as well as the area and shape information for the modules. Experimental results indicate that our algorithms perform well for many test problems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01553890
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  • 6
    Electronic Resource
    Electronic Resource
    Area minimization for hierarchical floorplans (1996)
    Springer
    Algorithmica 15 (1996), S. 550-571 
    Details
    ISSN: 1432-0541
    Keywords: Design automation ; VLSI layout ; Floorplanning ; Floorplan sizing ; Area minimization ; NP-complete ; Hierarchical floorplans ; Pseudopolynomial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract In this paper we study the area-minimization problem for hierarchical floorplans. We settle an open problem on the complexity of the area-minimization problem for hierarchical floorplans by showing it to be NP-complete (even for balanced hierarchical floorplans). We then present a new algorithm for determining the nonredundant realizations of a wheel. The algorithm has time costO(k 2 logk) and space cost0(k 2) if each block in a wheel has at mostk realizations. Based on the new algorithm for a wheel, we design a new pseudopolynomial area-minimization algorithm for hierarchical floorplans of order-5. The time and space costs of the algorithm are0((nM)2log(nM) and0(n 2 M), respectively, wheren is the number of basic blocks andM is an upper bound on the dimensions of the realizations of the basic blocks. The area-minimization algorithm was implemented. Experimental results show that it is very fast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01940881
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  • 7
    Electronic Resource
    Electronic Resource
    An Extremal Problem in Colored Uniform Hypergraphs (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 576 (1989), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1989.tb16438.x
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  • 8
    Electronic Resource
    Electronic Resource
    Formate dehydrogenase molybdenum and tungsten sites-observation by EXAFS of structural differences
    Amsterdam : Elsevier
    Journal of Inorganic Biochemistry 23 (1985), S. 119-124 
    Details
    ISSN: 0162-0134
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0162-0134(85)83015-4
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  • 9
    Electronic Resource
    Electronic Resource
    Environmental Isotope Characteristics of Landfill Leachates and Gases (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 34 (1996), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: The isotopic characteristics of municipal landfill leachate and gases (carbon dioxide and methane) are unique relative to the aqueous and gaseous media in most other natural geologic environments. The δ13C of the CO2 in landfills is significantly enriched in 13C, with values as high as +20 ‰ reported. The δ13C and δD values of the methane fall within a range of values representative of microbial methane produced primarily by the acetate-fermentation process. The δD of landfill leachate is strongly enriched in deuterium, by approximately 30 ‰ to nearly 60 ‰ relative to local average precipitation values. This deuterium enrichment is undoubtedly due to the extensive production of microbial methane within the limited reservoir of a landfill. The concentration of the radiogenic isotopes, 14C and 3H, are significantly elevated in both landfill leachate and methane. The 14C values range between approximately 120 and 170 pMC and can be explained by the input of organic material that was affected by the increased 14C content of atmospheric CO2 caused by atmospheric testing of nuclear devices. The tritium measured in leachate, however, is often too high to be explained by previous atmospheric levels and must come from material buried within the landfill. The unique isotopic characteristics observed in landfill leachates and gases provide a very useful technique for confirming whether contamination is from a municipal landfill or some other local source.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1996.tb02077.x
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  • 10
    Electronic Resource
    Electronic Resource
    Living donor liver transplantation for hepatitis C related hepatocellular carcinoma in a haemophilia A patient (2005)
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 11 (2005), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  We report the first case of unrelated living liver transplantation for hepatitis C related hepatocellular carcinoma (HCC) in a Chinese patient with haemophilia A. The development of cirrhosis and HCC was insidious in this patient, who has previously failed interferon treatment despite low viral load and genotype 6a. With factor VIII and novoseven support, there were no operative complications and there was no need for blood transfusion. Postoperative pegulated interferon treatment resulted in viral clearance with no increased cellular rejection. The use of living donors represent a potential life saving therapeutic options for hepatitis C virus related complications in haemophiliac, especially in countries of organ shortage. Careful patient and donor choice, meticulous surgical expertise and proper counselling, however, are prudent requirements.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2516.2005.00945.x
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